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Results: 1 to 20 of 80

1.

Distinct structural elements in the first membrane-spanning segment of the epithelial sodium channel.

Kashlan OB, Maarouf AB, Kussius C, Denshaw RM, Blumenthal KM, Kleyman TR.

J Biol Chem. 2006 Oct 13;281(41):30455-62. Epub 2006 Aug 14.

PMID:
16912051
[PubMed - indexed for MEDLINE]
Free Article
2.

Emerging issues of connexin channels: biophysics fills the gap.

Harris AL.

Q Rev Biophys. 2001 Aug;34(3):325-472. Review. Erratum in: Q Rev Biophys 2002 Feb;35(1):109.

PMID:
11838236
[PubMed - indexed for MEDLINE]
3.

Insight toward epithelial Na+ channel mechanism revealed by the acid-sensing ion channel 1 structure.

Stockand JD, Staruschenko A, Pochynyuk O, Booth RE, Silverthorn DU.

IUBMB Life. 2008 Sep;60(9):620-8. doi: 10.1002/iub.89. Review.

PMID:
18459164
[PubMed - indexed for MEDLINE]
4.

Role of the C-terminal part of the extracellular domain of the alpha-ENaC in activation by sulfonylurea glibenclamide.

Renauld S, Chraibi A.

J Membr Biol. 2009 Aug;230(3):133-41. doi: 10.1007/s00232-009-9193-1. Epub 2009 Aug 21.

PMID:
19696956
[PubMed - indexed for MEDLINE]
5.

Mutations in the pore region modify epithelial sodium channel gating by shear stress.

Carattino MD, Sheng S, Kleyman TR.

J Biol Chem. 2005 Feb 11;280(6):4393-401. Epub 2004 Nov 29.

PMID:
15569663
[PubMed - indexed for MEDLINE]
Free Article
6.

Second transmembrane domains of ENaC subunits contribute to ion permeation and selectivity.

Sheng S, McNulty KA, Harvey JM, Kleyman TR.

J Biol Chem. 2001 Nov 23;276(47):44091-8. Epub 2001 Sep 19.

PMID:
11564745
[PubMed - indexed for MEDLINE]
Free Article
7.

Cys palmitoylation of the beta subunit modulates gating of the epithelial sodium channel.

Mueller GM, Maarouf AB, Kinlough CL, Sheng N, Kashlan OB, Okumura S, Luthy S, Kleyman TR, Hughey RP.

J Biol Chem. 2010 Oct 1;285(40):30453-62. doi: 10.1074/jbc.M110.151845. Epub 2010 Jul 27.

PMID:
20663869
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Epithelial sodium channel pore region. structure and role in gating.

Sheng S, Li J, McNulty KA, Kieber-Emmons T, Kleyman TR.

J Biol Chem. 2001 Jan 12;276(2):1326-34.

PMID:
11022046
[PubMed - indexed for MEDLINE]
Free Article
9.

Identification of the roles of conserved charged residues in the extracellular domain of an epithelial sodium channel (ENaC) subunit by alanine mutagenesis.

Edelheit O, Hanukoglu I, Dascal N, Hanukoglu A.

Am J Physiol Renal Physiol. 2011 Apr;300(4):F887-97. doi: 10.1152/ajprenal.00648.2010. Epub 2011 Jan 5.

PMID:
21209000
[PubMed - indexed for MEDLINE]
Free Article
10.
11.

Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels.

Diakov A, Bera K, Mokrushina M, Krueger B, Korbmacher C.

J Physiol. 2008 Oct 1;586(Pt 19):4587-608. doi: 10.1113/jphysiol.2008.154435. Epub 2008 Jul 31.

PMID:
18669538
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Characterization of the selectivity filter of the epithelial sodium channel.

Sheng S, Li J, McNulty KA, Avery D, Kleyman TR.

J Biol Chem. 2000 Mar 24;275(12):8572-81.

PMID:
10722696
[PubMed - indexed for MEDLINE]
Free Article
13.

Charged residues in the M2 region of alpha-hENaC play a role in channel conductance.

Langloh AL, Berdiev B, Ji HL, Keyser K, Stanton BA, Benos DJ.

Am J Physiol Cell Physiol. 2000 Feb;278(2):C277-91.

PMID:
10666023
[PubMed - indexed for MEDLINE]
Free Article
14.

Regulation of epithelial sodium channel activity through a region of the carboxyl terminus of the alpha -subunit. Evidence for intracellular kinase-mediated reactions.

Volk KA, Snyder PM, Stokes JB.

J Biol Chem. 2001 Nov 23;276(47):43887-93. Epub 2001 Sep 24.

PMID:
11571309
[PubMed - indexed for MEDLINE]
Free Article
15.

Functional role of extracellular loop cysteine residues of the epithelial Na+ channel in Na+ self-inhibition.

Sheng S, Maarouf AB, Bruns JB, Hughey RP, Kleyman TR.

J Biol Chem. 2007 Jul 13;282(28):20180-90. Epub 2007 May 23.

PMID:
17522058
[PubMed - indexed for MEDLINE]
Free Article
16.

On the interaction between amiloride and its putative alpha-subunit epithelial Na+ channel binding site.

Kashlan OB, Sheng S, Kleyman TR.

J Biol Chem. 2005 Jul 15;280(28):26206-15. Epub 2005 May 20.

PMID:
15908426
[PubMed - indexed for MEDLINE]
Free Article
17.

Multiple epithelial Na+ channel domains participate in subunit assembly.

Bruns JB, Hu B, Ahn YJ, Sheng S, Hughey RP, Kleyman TR.

Am J Physiol Renal Physiol. 2003 Oct;285(4):F600-9. Epub 2003 May 27.

PMID:
12770839
[PubMed - indexed for MEDLINE]
Free Article
18.

A single point mutation in the pore region of the epithelial Na+ channel changes ion selectivity by modifying molecular sieving.

Kellenberger S, Gautschi I, Schild L.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4170-5.

PMID:
10097182
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A critical role for transmembrane segment IVS6 of the sodium channel alpha subunit in fast inactivation.

McPhee JC, Ragsdale DS, Scheuer T, Catterall WA.

J Biol Chem. 1995 May 19;270(20):12025-34.

PMID:
7744852
[PubMed - indexed for MEDLINE]
Free Article
20.

The cytosolic termini of the beta- and gamma-ENaC subunits are involved in the functional interactions between cystic fibrosis transmembrane conductance regulator and epithelial sodium channel.

Ji HL, Chalfant ML, Jovov B, Lockhart JP, Parker SB, Fuller CM, Stanton BA, Benos DJ.

J Biol Chem. 2000 Sep 8;275(36):27947-56.

PMID:
10821834
[PubMed - indexed for MEDLINE]
Free Article
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