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Results: 1 to 20 of 153

1.

Reversal of HCN channel voltage dependence via bridging of the S4-S5 linker and Post-S6.

Prole DL, Yellen G.

J Gen Physiol. 2006 Sep;128(3):273-82. Epub 2006 Aug 14.

PMID:
16908727
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Structural changes during HCN channel gating defined by high affinity metal bridges.

Kwan DC, Prole DL, Yellen G.

J Gen Physiol. 2012 Sep;140(3):279-91. doi: 10.1085/jgp.201210838.

PMID:
22930802
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Voltage-dependent gating of hyperpolarization-activated, cyclic nucleotide-gated pacemaker channels: molecular coupling between the S4-S5 and C-linkers.

Decher N, Chen J, Sanguinetti MC.

J Biol Chem. 2004 Apr 2;279(14):13859-65. Epub 2004 Jan 15.

PMID:
14726518
[PubMed - indexed for MEDLINE]
Free Article
4.

The S4-S5 linker couples voltage sensing and activation of pacemaker channels.

Chen J, Mitcheson JS, Tristani-Firouzi M, Lin M, Sanguinetti MC.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11277-82. Epub 2001 Sep 11.

PMID:
11553787
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

S4 movement in a mammalian HCN channel.

Vemana S, Pandey S, Larsson HP.

J Gen Physiol. 2004 Jan;123(1):21-32. Epub 2003 Dec 15.

PMID:
14676284
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Changes in local S4 environment provide a voltage-sensing mechanism for mammalian hyperpolarization-activated HCN channels.

Bell DC, Yao H, Saenger RC, Riley JH, Siegelbaum SA.

J Gen Physiol. 2004 Jan;123(1):5-19. Epub 2003 Dec 15.

PMID:
14676285
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Slow conformational changes of the voltage sensor during the mode shift in hyperpolarization-activated cyclic-nucleotide-gated channels.

Bruening-Wright A, Larsson HP.

J Neurosci. 2007 Jan 10;27(2):270-8.

PMID:
17215386
[PubMed - indexed for MEDLINE]
Free Article
8.

Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.

Männikkö R, Elinder F, Larsson HP.

Nature. 2002 Oct 24;419(6909):837-41.

PMID:
12397358
[PubMed - indexed for MEDLINE]
9.

Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels.

Chen S, Wang J, Zhou L, George MS, Siegelbaum SA.

J Gen Physiol. 2007 Feb;129(2):175-88.

PMID:
17261842
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Emerging issues of connexin channels: biophysics fills the gap.

Harris AL.

Q Rev Biophys. 2001 Aug;34(3):325-472. Review. Erratum in: Q Rev Biophys 2002 Feb;35(1):109.

PMID:
11838236
[PubMed - indexed for MEDLINE]
11.

Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.

Chen J, Mitcheson JS, Lin M, Sanguinetti MC.

J Biol Chem. 2000 Nov 17;275(46):36465-71.

PMID:
10962006
[PubMed - indexed for MEDLINE]
Free Article
12.
13.

Sensitivity of HCN channel deactivation to cAMP is amplified by an S4 mutation combined with activation mode shift.

Wicks NL, Chan KS, Madden Z, Santoro B, Young EC.

Pflugers Arch. 2009 Sep;458(5):877-89. doi: 10.1007/s00424-009-0687-6. Epub 2009 Jun 21.

PMID:
19544068
[PubMed - indexed for MEDLINE]
14.

Voltage-controlled gating at the intracellular entrance to a hyperpolarization-activated cation channel.

Rothberg BS, Shin KS, Phale PS, Yellen G.

J Gen Physiol. 2002 Jan;119(1):83-91.

PMID:
11773240
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Histidine 518 in the S6-CNBD linker controls pH dependence and gating of HCN channel from sea-urchin sperm.

Mistrík P, Torre V.

Pflugers Arch. 2004 Apr;448(1):76-84. Epub 2004 Feb 6.

PMID:
14767770
[PubMed - indexed for MEDLINE]
16.

A new hyperpolarization-activated, cyclic nucleotide-gated channel from sea urchin sperm flagella.

Galindo BE, Neill AT, Vacquier VD.

Biochem Biophys Res Commun. 2005 Aug 19;334(1):96-101.

PMID:
15992765
[PubMed - indexed for MEDLINE]
17.

Voltage sensing and activation gating of HCN pacemaker channels.

Chen J, Piper DR, Sanguinetti MC.

Trends Cardiovasc Med. 2002 Jan;12(1):42-5. Review.

PMID:
11796244
[PubMed - indexed for MEDLINE]
18.

Molecular compatibility of the channel gate and the N terminus of S5 segment for voltage-gated channel activity.

Caprini M, Fava M, Valente P, Fernandez-Ballester G, Rapisarda C, Ferroni S, Ferrer-Montiel A.

J Biol Chem. 2005 May 6;280(18):18253-64. Epub 2005 Mar 4.

PMID:
15749711
[PubMed - indexed for MEDLINE]
Free Article
19.

The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a'-go-go-related gene (hERG) K+ channel.

Ferrer T, Rupp J, Piper DR, Tristani-Firouzi M.

J Biol Chem. 2006 May 5;281(18):12858-64. Epub 2006 Mar 8.

PMID:
16524878
[PubMed - indexed for MEDLINE]
Free Article
20.

Cellular context and multiple channel domains determine cAMP sensitivity of HCN4 channels: ligand-independent relief of autoinhibition in HCN4.

Liao Z, Lockhead D, St Clair JR, Larson ED, Wilson CE, Proenza C.

J Gen Physiol. 2012 Nov;140(5):557-66. doi: 10.1085/jgp.201210858.

PMID:
23109717
[PubMed - indexed for MEDLINE]
Free PMC Article

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