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Results: 1 to 20 of 134

1.

Plasma protein beta-2-glycoprotein 1 mediates interaction between the anti-tumor monoclonal antibody 3G4 and anionic phospholipids on endothelial cells.

Luster TA, He J, Huang X, Maiti SN, Schroit AJ, de Groot PG, Thorpe PE.

J Biol Chem. 2006 Oct 6;281(40):29863-71. Epub 2006 Aug 10.

PMID:
16905548
[PubMed - indexed for MEDLINE]
Free Article
2.

Antitumor effects of a monoclonal antibody that binds anionic phospholipids on the surface of tumor blood vessels in mice.

Ran S, He J, Huang X, Soares M, Scothorn D, Thorpe PE.

Clin Cancer Res. 2005 Feb 15;11(4):1551-62.

PMID:
15746060
[PubMed - indexed for MEDLINE]
Free Article
3.
4.

Increased exposure of anionic phospholipids on the surface of tumor blood vessels.

Ran S, Downes A, Thorpe PE.

Cancer Res. 2002 Nov 1;62(21):6132-40.

PMID:
12414638
[PubMed - indexed for MEDLINE]
Free Article
5.

Combination of a monoclonal anti-phosphatidylserine antibody with gemcitabine strongly inhibits the growth and metastasis of orthotopic pancreatic tumors in mice.

Beck AW, Luster TA, Miller AF, Holloway SE, Conner CR, Barnett CC, Thorpe PE, Fleming JB, Brekken RA.

Int J Cancer. 2006 May 15;118(10):2639-43.

PMID:
16353142
[PubMed - indexed for MEDLINE]
6.

Human beta 2-glycoprotein I binds to endothelial cells through a cluster of lysine residues that are critical for anionic phospholipid binding and offers epitopes for anti-beta 2-glycoprotein I antibodies.

Del Papa N, Sheng YH, Raschi E, Kandiah DA, Tincani A, Khamashta MA, Atsumi T, Hughes GR, Ichikawa K, Koike T, Balestrieri G, Krilis SA, Meroni PL.

J Immunol. 1998 Jun 1;160(11):5572-8.

PMID:
9605162
[PubMed - indexed for MEDLINE]
Free Article
7.

Phosphatidylserine expression on cell surfaces promotes antibody-dependent aggregation and thrombosis in beta2-glycoprotein I-immune mice.

Dombroski D, Balasubramanian K, Schroit AJ.

J Autoimmun. 2000 May;14(3):221-9.

PMID:
10756084
[PubMed - indexed for MEDLINE]
8.

Radiation-enhanced vascular targeting of human lung cancers in mice with a monoclonal antibody that binds anionic phospholipids.

He J, Luster TA, Thorpe PE.

Clin Cancer Res. 2007 Sep 1;13(17):5211-8.

PMID:
17785577
[PubMed - indexed for MEDLINE]
Free Article
9.

Anti-endothelial cell antibody binding makes negatively charged phospholipids accessible to antiphospholipid antibodies.

Bordron A, Dueymes M, Levy Y, Jamin C, Ziporen L, Piette JC, Shoenfeld Y, Youinou P.

Arthritis Rheum. 1998 Oct;41(10):1738-47.

PMID:
9778215
[PubMed - indexed for MEDLINE]
10.

[74As]-Labeled monoclonal antibody against anionic phospholipids.

Chopra A.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2008 Apr 14 [updated 2008 May 27].

PMID:
20641667
[PubMed]
Books & Documents
11.

Phosphatidylserine is a marker of tumor vasculature and a potential target for cancer imaging and therapy.

Ran S, Thorpe PE.

Int J Radiat Oncol Biol Phys. 2002 Dec 1;54(5):1479-84.

PMID:
12459374
[PubMed - indexed for MEDLINE]
12.

Recruitment of beta-2-glycoprotein 1 to cell surfaces in extrinsic and intrinsic apoptosis.

Balasubramanian K, Maiti SN, Schroit AJ.

Apoptosis. 2005 Mar;10(2):439-46.

PMID:
15843904
[PubMed - indexed for MEDLINE]
13.

Coincident exposure of phosphatidylethanolamine and anionic phospholipids on the surface of irradiated cells.

Marconescu A, Thorpe PE.

Biochim Biophys Acta. 2008 Oct;1778(10):2217-24. doi: 10.1016/j.bbamem.2008.05.006. Epub 2008 May 28.

PMID:
18570887
[PubMed - indexed for MEDLINE]
Free Article
14.

Beta(2)-glycoprotein I promotes the binding of anionic phospholipid vesicles by macrophages.

Thiagarajan P, Le A, Benedict CR.

Arterioscler Thromb Vasc Biol. 1999 Nov;19(11):2807-11.

PMID:
10559030
[PubMed - indexed for MEDLINE]
Free Article
15.

Interaction of beta2-glycoprotein 1 with phosphatidylserine-containing membranes: ligand-dependent conformational alterations initiate bivalent binding.

Hamdan R, Maiti SN, Schroit AJ.

Biochemistry. 2007 Sep 18;46(37):10612-20. Epub 2007 Aug 23.

PMID:
17715943
[PubMed - indexed for MEDLINE]
16.

Role of divalency in the high-affinity binding of anticardiolipin antibody-beta 2-glycoprotein I complexes to lipid membranes.

Willems GM, Janssen MP, Pelsers MM, Comfurius P, Galli M, Zwaal RF, Bevers EM.

Biochemistry. 1996 Oct 29;35(43):13833-42.

PMID:
8901526
[PubMed - indexed for MEDLINE]
17.

Monoclonal IgM antiphosphatidylserine antibody reacts against cytoskeleton-like structures in cultured human umbilical cord endothelial cells.

Lin L, Shroyer L, Walter A, Lyden TW, Ng AK, Rote NS.

Am J Reprod Immunol. 1995 Jan;33(1):97-107.

PMID:
7542455
[PubMed - indexed for MEDLINE]
18.

The binding of some human antiendothelial cell antibodies induces endothelial cell apoptosis.

Bordron A, Dueymes M, Levy Y, Jamin C, Leroy JP, Piette JC, Shoenfeld Y, Youinou PY.

J Clin Invest. 1998 May 15;101(10):2029-35.

PMID:
9593758
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Binding of endostatin to phosphatidylserine-containing membranes and formation of amyloid-like fibers.

Zhao H, Jutila A, Nurminen T, Wickström SA, Keski-Oja J, Kinnunen PK.

Biochemistry. 2005 Mar 1;44(8):2857-63.

PMID:
15723529
[PubMed - indexed for MEDLINE]
20.

Localization of beta2-glycoprotein 1 in late endosomes of human endothelial cells.

Dunoyer-Geindre S, Kruithof EK, Galve-de Rochemonteix B, Rosnoblet C, Gruenberg J, Reber G, de Moerloose P.

Thromb Haemost. 2001 May;85(5):903-7.

PMID:
11372686
[PubMed - indexed for MEDLINE]

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