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Items: 1 to 20 of 141

1.

Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

Guo W, Pylayeva Y, Pepe A, Yoshioka T, Muller WJ, Inghirami G, Giancotti FG.

Cell. 2006 Aug 11;126(3):489-502.

2.

Co-opted integrin signaling in ErbB2-induced mammary tumor progression.

Carraway KL 3rd, Sweeney C.

Cancer Cell. 2006 Aug;10(2):93-5. Review.

3.

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling.

Brantley-Sieders DM, Zhuang G, Hicks D, Fang WB, Hwang Y, Cates JM, Coffman K, Jackson D, Bruckheimer E, Muraoka-Cook RS, Chen J.

J Clin Invest. 2008 Jan;118(1):64-78.

4.

ErbB2 makes beta 4 integrin an accomplice in tumorigenesis.

Muthuswamy SK.

Cell. 2006 Aug 11;126(3):443-5. Review.

5.

Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth.

Yen L, Cao Z, Wu X, Ingalla ER, Baron C, Young LJ, Gregg JP, Cardiff RD, Borowsky AD, Sweeney C, Carraway KL 3rd.

Cancer Res. 2006 Dec 1;66(23):11279-86.

6.
7.

Developmental timing of activated erbB2 expression plays a critical role in the induction of mammary tumors.

Andrechek ER, Muller WJ.

Cell Cycle. 2004 Sep;3(9):1111-3. Epub 2004 Sep 1. Review.

PMID:
15326381
8.

Distinct ErbB-2 coupled signaling pathways promote mammary tumors with unique pathologic and transcriptional profiles.

Schade B, Lam SH, Cernea D, Sanguin-Gendreau V, Cardiff RD, Jung BL, Hallett M, Muller WJ.

Cancer Res. 2007 Aug 15;67(16):7579-88.

9.

Cooperating oncogenic events in murine mammary tumorigenesis: assessment of ErbB2, mutant p53, and mouse mammary tumor virus.

Zelazny E, Li B, Anagnostopoulos AM, Coleman A, Perkins AS.

Exp Mol Pathol. 2001 Jun;70(3):183-93.

PMID:
11417997
10.

Estrogenic promotion of ErbB2 tyrosine kinase activity in mammary tumor cells requires activation of ErbB3 signaling.

Liu B, Ordonez-Ercan D, Fan Z, Huang X, Edgerton SM, Yang X, Thor AD.

Mol Cancer Res. 2009 Nov;7(11):1882-92. doi: 10.1158/1541-7786.MCR-08-0509. Epub 2009 Oct 27.

11.

p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.

Hulit J, Lee RJ, Li Z, Wang C, Katiyar S, Yang J, Quong AA, Wu K, Albanese C, Russell R, Di Vizio D, Koff A, Thummala S, Zhang H, Harrell J, Sun H, Muller WJ, Inghirami G, Lisanti MP, Pestell RG.

Cancer Res. 2006 Sep 1;66(17):8529-41.

12.

beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression.

Huck L, Pontier SM, Zuo DM, Muller WJ.

Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15559-64. doi: 10.1073/pnas.1003034107. Epub 2010 Aug 16.

13.

ERBB2-mediated transcriptional up-regulation of the alpha5beta1 integrin fibronectin receptor promotes tumor cell survival under adverse conditions.

Spangenberg C, Lausch EU, Trost TM, Prawitt D, May A, Keppler R, Fees SA, Reutzel D, Bell C, Schmitt S, Schiffer IB, Weber A, Brenner W, Hermes M, Sahin U, Türeci O, Koelbl H, Hengstler JG, Zabel BU.

Cancer Res. 2006 Apr 1;66(7):3715-25.

15.

Protein tyrosine kinase 6 promotes ERBB2-induced mammary gland tumorigenesis in the mouse.

Peng M, Ball-Kell SM, Tyner AL.

Cell Death Dis. 2015 Aug 6;6:e1848. doi: 10.1038/cddis.2015.210.

16.

Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development.

Ursini-Siegel J, Rajput AB, Lu H, Sanguin-Gendreau V, Zuo D, Papavasiliou V, Lavoie C, Turpin J, Cianflone K, Huntsman DG, Muller WJ.

Mol Cell Biol. 2007 Sep;27(18):6361-71. Epub 2007 Jul 16.

17.

Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis.

Julien SG, Dubé N, Read M, Penney J, Paquet M, Han Y, Kennedy BP, Muller WJ, Tremblay ML.

Nat Genet. 2007 Mar;39(3):338-46. Epub 2007 Jan 28.

PMID:
17259984
18.

ErbB2 activation and signal transduction in normal and malignant mammary cells.

Hynes NE.

J Mammary Gland Biol Neoplasia. 1996 Apr;1(2):199-206. Review.

PMID:
10887493
19.

Interleukin-24 induces expression of beta4 integrin but suppresses anchorage-independent growth of rat mammary tumor cells by a mechanism that is independent of beta4.

Xuan W, Li YJ, Liu G, Ben-David Y, Archer MC.

Mol Cancer Res. 2009 Mar;7(3):433-42. doi: 10.1158/1541-7786.MCR-08-0252. Epub 2009 Mar 3.

20.

Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion.

Hutchinson JN, Jin J, Cardiff RD, Woodgett JR, Muller WJ.

Cancer Res. 2004 May 1;64(9):3171-8.

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