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Results: 1 to 20 of 112

1.

Peptide neuroprotection through specific interaction with brain tubulin.

Divinski I, Holtser-Cochav M, Vulih-Schultzman I, Steingart RA, Gozes I.

J Neurochem. 2006 Aug;98(3):973-84.

PMID:
16893427
[PubMed - indexed for MEDLINE]
2.

NAP and D-SAL: neuroprotection against the beta amyloid peptide (1-42).

Gozes I, Divinski I, Piltzer I.

BMC Neurosci. 2008 Dec 10;9 Suppl 3:S3. doi: 10.1186/1471-2202-9-S3-S3.

PMID:
19091000
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

NAP, a neuroprotective drug candidate in clinical trials, stimulates microtubule assembly in the living cell.

Gozes I, Divinski I.

Curr Alzheimer Res. 2007 Dec;4(5):507-9.

PMID:
18220512
[PubMed - indexed for MEDLINE]
4.

Tubulin is the target binding site for NAP-related peptides: ADNF-9, D-NAP, and D-SAL.

Holtser-Cochav M, Divinski I, Gozes I.

J Mol Neurosci. 2006;28(3):303-7.

PMID:
16691018
[PubMed - indexed for MEDLINE]
5.

The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activities.

Oz S, Ivashko-Pachima Y, Gozes I.

PLoS One. 2012;7(12):e51458. doi: 10.1371/journal.pone.0051458. Epub 2012 Dec 14.

PMID:
23272107
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The femtomolar-acting NAP interacts with microtubules: Novel aspects of astrocyte protection.

Gozes I, Divinski I.

J Alzheimers Dis. 2004 Dec;6(6 Suppl):S37-41.

PMID:
15665412
[PubMed - indexed for MEDLINE]
7.

Novel tubulin and tau neuroprotective fragments sharing structural similarities with the drug candidate NAP (Davuentide).

Gozes I, Iram T, Maryanovsky E, Arviv C, Rozenberg L, Schirer Y, Giladi E, Furman-Assaf S.

J Alzheimers Dis. 2014;40 Suppl 1:S23-36. doi: 10.3233/JAD-131664.

PMID:
24503616
[PubMed - indexed for MEDLINE]
8.

NAP protects against cyanide-related microtubule destruction.

Zemlyak I, Sapolsky R, Gozes I.

J Neural Transm. 2009 Nov;116(11):1411-6. doi: 10.1007/s00702-009-0252-7. Epub 2009 Jun 24.

PMID:
19551468
[PubMed - indexed for MEDLINE]
9.

A femtomolar acting octapeptide interacts with tubulin and protects astrocytes against zinc intoxication.

Divinski I, Mittelman L, Gozes I.

J Biol Chem. 2004 Jul 2;279(27):28531-8. Epub 2004 Apr 29.

PMID:
15123709
[PubMed - indexed for MEDLINE]
Free Article
10.

NAP and ADNF-9 protect normal and Down's syndrome cortical neurons from oxidative damage and apoptosis.

Busciglio J, Pelsman A, Helguera P, Ashur-Fabian O, Pinhasov A, Brenneman DE, Gozes I.

Curr Pharm Des. 2007;13(11):1091-8.

PMID:
17430172
[PubMed - indexed for MEDLINE]
11.

G protein betagamma subunits interact with alphabeta- and gamma-tubulin and play a role in microtubule assembly in PC12 cells.

Montoya V, Gutierrez C, Najera O, Leony D, Varela-Ramirez A, Popova J, Rasenick MM, Das S, Roychowdhury S.

Cell Motil Cytoskeleton. 2007 Dec;64(12):936-50.

PMID:
17705289
[PubMed - indexed for MEDLINE]
12.

Protection against tauopathy by the drug candidates NAP (davunetide) and D-SAL: biochemical, cellular and behavioral aspects.

Shiryaev N, Pikman R, Giladi E, Gozes I.

Curr Pharm Des. 2011;17(25):2603-12. Review.

PMID:
21728979
[PubMed - indexed for MEDLINE]
13.

From vasoactive intestinal peptide (VIP) through activity-dependent neuroprotective protein (ADNP) to NAP: a view of neuroprotection and cell division.

Gozes I, Divinsky I, Pilzer I, Fridkin M, Brenneman DE, Spier AD.

J Mol Neurosci. 2003;20(3):315-22. Review.

PMID:
14501014
[PubMed - indexed for MEDLINE]
14.

NAP: research and development of a peptide derived from activity-dependent neuroprotective protein (ADNP).

Gozes I, Morimoto BH, Tiong J, Fox A, Sutherland K, Dangoor D, Holser-Cochav M, Vered K, Newton P, Aisen PS, Matsuoka Y, van Dyck CH, Thal L.

CNS Drug Rev. 2005 Winter;11(4):353-68. Review.

PMID:
16614735
[PubMed - indexed for MEDLINE]
15.

Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking.

Thissen JA, Gross JM, Subramanian K, Meyer T, Casey PJ.

J Biol Chem. 1997 Nov 28;272(48):30362-70.

PMID:
9374526
[PubMed - indexed for MEDLINE]
Free Article
16.

The microtubule interacting drug candidate NAP protects against kainic acid toxicity in a rat model of epilepsy.

Zemlyak I, Manley N, Vulih-Shultzman I, Cutler AB, Graber K, Sapolsky RM, Gozes I.

J Neurochem. 2009 Dec;111(5):1252-63. doi: 10.1111/j.1471-4159.2009.06415.x. Epub 2009 Oct 3.

PMID:
19799711
[PubMed - indexed for MEDLINE]
17.

Testosterone induces neuroprotection from oxidative stress. Effects on catalase activity and 3-nitro-L-tyrosine incorporation into alpha-tubulin in a mouse neuroblastoma cell line.

Chisu V, Manca P, Lepore G, Gadau S, Zedda M, Farina V.

Arch Ital Biol. 2006 May;144(2):63-73.

PMID:
16642786
[PubMed - indexed for MEDLINE]
18.
19.

NAP mechanisms of neuroprotection.

Gozes I, Steingart RA, Spier AD.

J Mol Neurosci. 2004;24(1):67-72.

PMID:
15314252
[PubMed - indexed for MEDLINE]
20.

Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage.

Matsuoka Y, Gray AJ, Hirata-Fukae C, Minami SS, Waterhouse EG, Mattson MP, LaFerla FM, Gozes I, Aisen PS.

J Mol Neurosci. 2007;31(2):165-70.

PMID:
17478890
[PubMed - indexed for MEDLINE]

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