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Results: 1 to 20 of 213

1.

Laulimalide and synthetic laulimalide analogues are synergistic with paclitaxel and 2-methoxyestradiol.

Clark EA, Hills PM, Davidson BS, Wender PA, Mooberry SL.

Mol Pharm. 2006 Jul-Aug;3(4):457-67.

PMID:
16889440
[PubMed - indexed for MEDLINE]
2.

Laulimalide and paclitaxel: a comparison of their effects on tubulin assembly and their synergistic action when present simultaneously.

Gapud EJ, Bai R, Ghosh AK, Hamel E.

Mol Pharmacol. 2004 Jul;66(1):113-21.

PMID:
15213302
[PubMed - indexed for MEDLINE]
Free Article
3.

Synergistic effects of peloruside A and laulimalide with taxoid site drugs, but not with each other, on tubulin assembly.

Hamel E, Day BW, Miller JH, Jung MK, Northcote PT, Ghosh AK, Curran DP, Cushman M, Nicolaou KC, Paterson I, Sorensen EJ.

Mol Pharmacol. 2006 Nov;70(5):1555-64. Epub 2006 Aug 3.

PMID:
16887932
[PubMed - indexed for MEDLINE]
Free Article
4.

The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity.

Pryor DE, O'Brate A, Bilcer G, Díaz JF, Wang Y, Wang Y, Kabaki M, Jung MK, Andreu JM, Ghosh AK, Giannakakou P, Hamel E.

Biochemistry. 2002 Jul 23;41(29):9109-15.

PMID:
12119025
[PubMed - indexed for MEDLINE]
5.

Microtubule-stabilizing agents based on designed laulimalide analogues.

Mooberry SL, Randall-Hlubek DA, Leal RM, Hegde SG, Hubbard RD, Zhang L, Wender PA.

Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8803-8. Epub 2004 May 25.

PMID:
15161976
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

In vitro and in vivo anticancer activities of synthetic (-)-laulimalide, a marine natural product microtubule stabilizing agent.

Liu J, Towle MJ, Cheng H, Saxton P, Reardon C, Wu J, Murphy EA, Kuznetsov G, Johannes CW, Tremblay MR, Zhao H, Pesant M, Fang FG, Vermeulen MW, Gallagher BM Jr, Littlefield BA.

Anticancer Res. 2007 May-Jun;27(3B):1509-18.

PMID:
17595769
[PubMed - indexed for MEDLINE]
Free Article
7.

Antiproliferative effects of 2-methoxyestradiol alone and in combination with chemotherapeutic agents on human endometrial cancer cells.

Chen CH, Lee WJ, Chang TC, Chen RJ, Chien CH, Chow SN.

Eur J Gynaecol Oncol. 2009;30(3):275-80.

PMID:
19697620
[PubMed - indexed for MEDLINE]
8.

Laulimalide and isolaulimalide, new paclitaxel-like microtubule-stabilizing agents.

Mooberry SL, Tien G, Hernandez AH, Plubrukarn A, Davidson BS.

Cancer Res. 1999 Feb 1;59(3):653-60.

PMID:
9973214
[PubMed - indexed for MEDLINE]
Free Article
9.

Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines.

Wilmes A, Bargh K, Kelly C, Northcote PT, Miller JH.

Mol Pharm. 2007 Mar-Apr;4(2):269-80.

PMID:
17397239
[PubMed - indexed for MEDLINE]
10.

Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells.

Honore S, Kamath K, Braguer D, Horwitz SB, Wilson L, Briand C, Jordan MA.

Cancer Res. 2004 Jul 15;64(14):4957-64.

PMID:
15256469
[PubMed - indexed for MEDLINE]
Free Article
11.

βII-tubulin and βIII-tubulin mediate sensitivity to peloruside A and laulimalide, but not paclitaxel or vinblastine, in human ovarian carcinoma cells.

Kanakkanthara A, Northcote PT, Miller JH.

Mol Cancer Ther. 2012 Feb;11(2):393-404. doi: 10.1158/1535-7163.MCT-11-0614. Epub 2011 Dec 16.

PMID:
22180309
[PubMed - indexed for MEDLINE]
Free Article
12.

Inhibitors of kinesin Eg5: antiproliferative activity of monastrol analogues against human glioblastoma cells.

Müller C, Gross D, Sarli V, Gartner M, Giannis A, Bernhardt G, Buschauer A.

Cancer Chemother Pharmacol. 2007 Feb;59(2):157-64. Epub 2006 May 16.

PMID:
16703323
[PubMed - indexed for MEDLINE]
13.

Novel 2-methoxyestradiol analogues with antitumor activity.

Tinley TL, Leal RM, Randall-Hlubek DA, Cessac JW, Wilkens LR, Rao PN, Mooberry SL.

Cancer Res. 2003 Apr 1;63(7):1538-49.

PMID:
12670902
[PubMed - indexed for MEDLINE]
Free Article
14.

Significant antitumor activity in vivo following treatment with the microtubule agent ENMD-1198.

LaVallee TM, Burke PA, Swartz GM, Hamel E, Agoston GE, Shah J, Suwandi L, Hanson AD, Fogler WE, Sidor CF, Treston AM.

Mol Cancer Ther. 2008 Jun;7(6):1472-82. doi: 10.1158/1535-7163.MCT-08-0107.

PMID:
18566218
[PubMed - indexed for MEDLINE]
Free Article
15.

Effects of Eg5 knockdown on human prostate cancer xenograft growth and chemosensitivity.

Hayashi N, Koller E, Fazli L, Gleave ME.

Prostate. 2008 Sep 1;68(12):1283-95. doi: 10.1002/pros.20783.

PMID:
18512732
[PubMed - indexed for MEDLINE]
16.

Preclinical pharmacologic evaluation of MST-997, an orally active taxane with superior in vitro and in vivo efficacy in paclitaxel- and docetaxel-resistant tumor models.

Sampath D, Greenberger LM, Beyer C, Hari M, Liu H, Baxter M, Yang S, Rios C, Discafani C.

Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3459-69.

PMID:
16740771
[PubMed - indexed for MEDLINE]
Free Article
17.

The novel combination of chlorpromazine and pentamidine exerts synergistic antiproliferative effects through dual mitotic action.

Lee MS, Johansen L, Zhang Y, Wilson A, Keegan M, Avery W, Elliott P, Borisy AA, Keith CT.

Cancer Res. 2007 Dec 1;67(23):11359-67.

PMID:
18056463
[PubMed - indexed for MEDLINE]
Free Article
18.

Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine.

Rathinasamy K, Jindal B, Asthana J, Singh P, Balaji PV, Panda D.

BMC Cancer. 2010 May 19;10:213. doi: 10.1186/1471-2407-10-213.

PMID:
20482847
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

In vitro synergy of paclitaxel (Taxol) and vinorelbine (navelbine) against human melanoma cell lines.

Photiou A, Shah P, Leong LK, Moss J, Retsas S.

Eur J Cancer. 1997 Mar;33(3):463-70.

PMID:
9155533
[PubMed - indexed for MEDLINE]
20.

STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells.

Newman SP, Foster PA, Stengel C, Day JM, Ho YT, Judde JG, Lassalle M, Prevost G, Leese MP, Potter BV, Reed MJ, Purohit A.

Clin Cancer Res. 2008 Jan 15;14(2):597-606. doi: 10.1158/1078-0432.CCR-07-1717.

PMID:
18223236
[PubMed - indexed for MEDLINE]
Free Article

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