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Results: 1 to 20 of 120

1.

Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton.

Kalfa TA, Pushkaran S, Mohandas N, Hartwig JH, Fowler VM, Johnson JF, Joiner CH, Williams DA, Zheng Y.

Blood. 2006 Dec 1;108(12):3637-45. Epub 2006 Aug 1.

PMID:
16882712
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Rac GTPases in erythroid biology.

Konstantinidis DG, George A, Kalfa TA.

Transfus Clin Biol. 2010 Sep;17(3):126-30. doi: 10.1016/j.tracli.2010.05.002. Epub 2010 Jul 23.

PMID:
20655266
[PubMed - indexed for MEDLINE]
3.

Altered phosphorylation of cytoskeleton proteins in sickle red blood cells: the role of protein kinase C, Rac GTPases, and reactive oxygen species.

George A, Pushkaran S, Li L, An X, Zheng Y, Mohandas N, Joiner CH, Kalfa TA.

Blood Cells Mol Dis. 2010 Jun 15;45(1):41-5. doi: 10.1016/j.bcmd.2010.02.006. Epub 2010 Mar 15. Review.

PMID:
20231105
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis.

Wang Y, Lebowitz D, Sun C, Thang H, Grynpas MD, Glogauer M.

J Bone Miner Res. 2008 Feb;23(2):260-70.

PMID:
17922611
[PubMed - indexed for MEDLINE]
5.

Rac1 and Rac2 regulate macrophage morphology but are not essential for migration.

Wheeler AP, Wells CM, Smith SD, Vega FM, Henderson RB, Tybulewicz VL, Ridley AJ.

J Cell Sci. 2006 Jul 1;119(Pt 13):2749-57. Epub 2006 Jun 13.

PMID:
16772332
[PubMed - indexed for MEDLINE]
Free Article
6.

Combined deletion of mouse dematin-headpiece and beta-adducin exerts a novel effect on the spectrin-actin junctions leading to erythrocyte fragility and hemolytic anemia.

Chen H, Khan AA, Liu F, Gilligan DM, Peters LL, Messick J, Haschek-Hock WM, Li X, Ostafin AE, Chishti AH.

J Biol Chem. 2007 Feb 9;282(6):4124-35. Epub 2006 Dec 2.

PMID:
17142833
[PubMed - indexed for MEDLINE]
Free Article
7.

Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development.

Guo F, Cancelas JA, Hildeman D, Williams DA, Zheng Y.

Blood. 2008 Sep 1;112(5):1767-75. doi: 10.1182/blood-2008-01-132068. Epub 2008 Jun 25.

PMID:
18579797
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen.

Kalfa TA, Pushkaran S, Zhang X, Johnson JF, Pan D, Daria D, Geiger H, Cancelas JA, Williams DA, Zheng Y.

Haematologica. 2010 Jan;95(1):27-35. doi: 10.3324/haematol.2009.006239.

PMID:
20065081
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Headpiece domain of dematin is required for the stability of the erythrocyte membrane.

Khanna R, Chang SH, Andrabi S, Azam M, Kim A, Rivera A, Brugnara C, Low PS, Liu SC, Chishti AH.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):6637-42.

PMID:
12011427
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Rac1 and Rac2 differentially regulate actin free barbed end formation downstream of the fMLP receptor.

Sun CX, Magalhães MA, Glogauer M.

J Cell Biol. 2007 Oct 22;179(2):239-45.

PMID:
17954607
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions.

Li S, Yamauchi A, Marchal CC, Molitoris JK, Quilliam LA, Dinauer MC.

J Immunol. 2002 Nov 1;169(9):5043-51.

PMID:
12391220
[PubMed - indexed for MEDLINE]
Free Article
12.

The erythrocyte skeletons of beta-adducin deficient mice have altered levels of tropomyosin, tropomodulin and EcapZ.

Porro F, Costessi L, Marro ML, Baralle FE, Muro AF.

FEBS Lett. 2004 Oct 8;576(1-2):36-40.

PMID:
15474006
[PubMed - indexed for MEDLINE]
13.

Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis.

Pestonjamasp KN, Forster C, Sun C, Gardiner EM, Bohl B, Weiner O, Bokoch GM, Glogauer M.

Blood. 2006 Oct 15;108(8):2814-20. Epub 2006 Jun 29.

PMID:
16809619
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis.

Hoppe AD, Swanson JA.

Mol Biol Cell. 2004 Aug;15(8):3509-19. Epub 2004 May 28.

PMID:
15169870
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Rac1 and Rac2 GTPases in haematopoiesis.

Weston VJ, Stankovic T.

Bioessays. 2004 Mar;26(3):221-4.

PMID:
14988923
[PubMed - indexed for MEDLINE]
16.

Rac GTPases play critical roles in early T-cell development.

Dumont C, Corsoni-Tadrzak A, Ruf S, de Boer J, Williams A, Turner M, Kioussis D, Tybulewicz VL.

Blood. 2009 Apr 23;113(17):3990-8. doi: 10.1182/blood-2008-09-181180. Epub 2008 Dec 16.

PMID:
19088377
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.

Mizukawa B, Wei J, Shrestha M, Wunderlich M, Chou FS, Griesinger A, Harris CE, Kumar AR, Zheng Y, Williams DA, Mulloy JC.

Blood. 2011 Nov 10;118(19):5235-45. doi: 10.1182/blood-2011-04-351817. Epub 2011 Sep 22.

PMID:
21940819
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Human neutrophils coordinate chemotaxis by differential activation of Rac1 and Rac2.

Zhang H, Sun C, Glogauer M, Bokoch GM.

J Immunol. 2009 Aug 15;183(4):2718-28. doi: 10.4049/jimmunol.0900849. Epub 2009 Jul 22.

PMID:
19625648
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases.

Gu Y, Filippi MD, Cancelas JA, Siefring JE, Williams EP, Jasti AC, Harris CE, Lee AW, Prabhakar R, Atkinson SJ, Kwiatkowski DJ, Williams DA.

Science. 2003 Oct 17;302(5644):445-9.

PMID:
14564009
[PubMed - indexed for MEDLINE]
Free Article
20.

Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles.

Yamauchi A, Kim C, Li S, Marchal CC, Towe J, Atkinson SJ, Dinauer MC.

J Immunol. 2004 Nov 15;173(10):5971-9.

PMID:
15528331
[PubMed - indexed for MEDLINE]
Free Article
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