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Items: 1 to 20 of 296

3.

Metabolic remodeling induced by mitochondrial aldehyde stress stimulates tolerance to oxidative stress in the heart.

Endo J, Sano M, Katayama T, Hishiki T, Shinmura K, Morizane S, Matsuhashi T, Katsumata Y, Zhang Y, Ito H, Nagahata Y, Marchitti S, Nishimaki K, Wolf AM, Nakanishi H, Hattori F, Vasiliou V, Adachi T, Ohsawa I, Taguchi R, Hirabayashi Y, Ohta S, Suematsu M, Ogawa S, Fukuda K.

Circ Res. 2009 Nov 20;105(11):1118-27. doi: 10.1161/CIRCRESAHA.109.206607. Epub 2009 Oct 8.

4.

Deficiency in a mitochondrial aldehyde dehydrogenase increases vulnerability to oxidative stress in PC12 cells.

Ohsawa I, Nishimaki K, Yasuda C, Kamino K, Ohta S.

J Neurochem. 2003 Mar;84(5):1110-7.

5.

Decreased proteolytic activity of the mitochondrial amyloid-β degrading enzyme, PreP peptidasome, in Alzheimer's disease brain mitochondria.

Alikhani N, Guo L, Yan S, Du H, Pinho CM, Chen JX, Glaser E, Yan SS.

J Alzheimers Dis. 2011;27(1):75-87. doi: 10.3233/JAD-2011-101716.

6.

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity.

Cardoso SM, Santana I, Swerdlow RH, Oliveira CR.

J Neurochem. 2004 Jun;89(6):1417-26.

7.

Mitochondrial ALDH2 deficiency as an oxidative stress.

Ohta S, Ohsawa I, Kamino K, Ando F, Shimokata H.

Ann N Y Acad Sci. 2004 Apr;1011:36-44.

PMID:
15126281
8.

Regional brain metabolism with cytochrome c oxidase histochemistry in a PS1/A246E mouse model of autosomal dominant Alzheimer's disease: correlations with behavior and oxidative stress.

Strazielle C, Jazi R, Verdier Y, Qian S, Lalonde R.

Neurochem Int. 2009 Dec;55(8):806-14. doi: 10.1016/j.neuint.2009.08.005. Epub 2009 Aug 12.

PMID:
19682525
9.

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice.

Hauptmann S, Scherping I, Dröse S, Brandt U, Schulz KL, Jendrach M, Leuner K, Eckert A, Müller WE.

Neurobiol Aging. 2009 Oct;30(10):1574-86. doi: 10.1016/j.neurobiolaging.2007.12.005. Epub 2008 Mar 4.

PMID:
18295378
10.
11.

Genetic deficiency of a mitochondrial aldehyde dehydrogenase increases serum lipid peroxides in community-dwelling females.

Ohsawa I, Kamino K, Nagasaka K, Ando F, Niino N, Shimokata H, Ohta S.

J Hum Genet. 2003;48(8):404-9. Epub 2003 Aug 7.

PMID:
12905081
12.

The role of cytochrome c oxidase deficient hippocampal neurones in Alzheimer's disease.

Cottrell DA, Borthwick GM, Johnson MA, Ince PG, Turnbull DM.

Neuropathol Appl Neurobiol. 2002 Oct;28(5):390-6.

PMID:
12366820
13.

Mitochondrial genomic contribution to mitochondrial dysfunction in Alzheimer's disease.

Onyango I, Khan S, Miller B, Swerdlow R, Trimmer P, Bennett P Jr.

J Alzheimers Dis. 2006 Jul;9(2):183-93. Review.

PMID:
16873965
14.
15.

Mitochondria and Alzheimer's disease: amyloid-beta peptide uptake and degradation by the presequence protease, hPreP.

Alikhani N, Ankarcrona M, Glaser E.

J Bioenerg Biomembr. 2009 Oct;41(5):447-51. doi: 10.1007/s10863-009-9244-4. Review.

PMID:
19798557
16.
17.

Cytoplasmic gelsolin increases mitochondrial activity and reduces Abeta burden in a mouse model of Alzheimer's disease.

Antequera D, Vargas T, Ugalde C, Spuch C, Molina JA, Ferrer I, Bermejo-Pareja F, Carro E.

Neurobiol Dis. 2009 Oct;36(1):42-50. doi: 10.1016/j.nbd.2009.06.018. Epub 2009 Jul 14.

PMID:
19607917
18.

Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease.

Aliyev A, Chen SG, Seyidova D, Smith MA, Perry G, de la Torre J, Aliev G.

J Neurol Sci. 2005 Mar 15;229-230:285-92. Epub 2004 Dec 23.

PMID:
15760652
19.

Age-dependent neurodegeneration accompanying memory loss in transgenic mice defective in mitochondrial aldehyde dehydrogenase 2 activity.

Ohsawa I, Nishimaki K, Murakami Y, Suzuki Y, Ishikawa M, Ohta S.

J Neurosci. 2008 Jun 11;28(24):6239-49. doi: 10.1523/JNEUROSCI.4956-07.2008.

20.

Mitochondrial dysfunction and Alzheimer's disease.

Chen X, Stern D, Yan SD.

Curr Alzheimer Res. 2006 Dec;3(5):515-20. Review.

PMID:
17168650
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