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Results: 1 to 20 of 107

1.

Functional domains of human tryptophan hydroxylase 2 (hTPH2).

Carkaci-Salli N, Flanagan JM, Martz MK, Salli U, Walther DJ, Bader M, Vrana KE.

J Biol Chem. 2006 Sep 22;281(38):28105-12. Epub 2006 Jul 24.

PMID:
16864580
[PubMed - indexed for MEDLINE]
Free Article
2.

Influence of human tryptophan hydroxylase 2 N- and C-terminus on enzymatic activity and oligomerization.

Tenner K, Walther D, Bader M.

J Neurochem. 2007 Sep;102(6):1887-94. Epub 2007 Jun 1.

PMID:
17539919
[PubMed - indexed for MEDLINE]
3.

Identification of amino-terminal sequences contributing to tryptophan hydroxylase tetramer formation.

Yohrling GJ 4th, Mockus SM, Vrana KE.

J Mol Neurosci. 1999 Feb;12(1):23-34.

PMID:
10636468
[PubMed - indexed for MEDLINE]
4.

Different properties of the central and peripheral forms of human tryptophan hydroxylase.

McKinney J, Knappskog PM, Haavik J.

J Neurochem. 2005 Jan;92(2):311-20.

PMID:
15663479
[PubMed - indexed for MEDLINE]
5.

Characterization of wild-type and mutant forms of human tryptophan hydroxylase 2.

Winge I, McKinney JA, Knappskog PM, Haavik J.

J Neurochem. 2007 Mar;100(6):1648-57. Epub 2006 Dec 23.

PMID:
17181551
[PubMed - indexed for MEDLINE]
6.

Carboxyl terminal deletion analysis of tryptophan hydroxylase.

Mockus SM, Kumer SC, Vrana KE.

Biochim Biophys Acta. 1997 Oct 17;1342(2):132-40.

PMID:
9392522
[PubMed - indexed for MEDLINE]
Free Article
7.

Functional properties of missense variants of human tryptophan hydroxylase 2.

McKinney JA, Turel B, Winge I, Knappskog PM, Haavik J.

Hum Mutat. 2009 May;30(5):787-94. doi: 10.1002/humu.20956.

PMID:
19319927
[PubMed - indexed for MEDLINE]
8.

Identification of substrate orienting and phosphorylation sites within tryptophan hydroxylase using homology-based molecular modeling.

Jiang GC, Yohrling GJ 4th, Schmitt JD, Vrana KE.

J Mol Biol. 2000 Sep 29;302(4):1005-17. Erratum in: J Mol Biol 2000 Nov 10;303(5):845. Yohrling, GJ [corrected to Yohrling, GJ 4th]; Schmitt, IV [corrected to Schmitt, JD].

PMID:
10993738
[PubMed - indexed for MEDLINE]
9.

A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression.

Murphy KL, Zhang X, Gainetdinov RR, Beaulieu JM, Caron MG.

J Biol Chem. 2008 May 9;283(19):13216-24. doi: 10.1074/jbc.M706749200. Epub 2008 Mar 13.

PMID:
18339632
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Activation and stabilization of human tryptophan hydroxylase 2 by phosphorylation and 14-3-3 binding.

Winge I, McKinney JA, Ying M, D'Santos CS, Kleppe R, Knappskog PM, Haavik J.

Biochem J. 2008 Feb 15;410(1):195-204.

PMID:
17973628
[PubMed - indexed for MEDLINE]
Free Article
11.

Intersubunit binding domains within tyrosine hydroxylase and tryptophan hydroxylase.

Yohrling GJ 4th, Jiang GC, Mockus SM, Vrana KE.

J Neurosci Res. 2000 Aug 1;61(3):313-20.

PMID:
10900078
[PubMed - indexed for MEDLINE]
12.

A chimeric tyrosine/tryptophan hydroxylase. The tyrosine hydroxylase regulatory domain serves to stabilize enzyme activity.

Mockus SM, Kumer SC, Vrana KE.

J Mol Neurosci. 1997 Aug;9(1):35-48.

PMID:
9356925
[PubMed - indexed for MEDLINE]
13.

Crystal structure of tryptophan hydroxylase with bound amino acid substrate.

Windahl MS, Petersen CR, Christensen HE, Harris P.

Biochemistry. 2008 Nov 18;47(46):12087-94. doi: 10.1021/bi8015263. Epub 2008 Oct 21.

PMID:
18937498
[PubMed - indexed for MEDLINE]
14.

Advances in the molecular characterization of tryptophan hydroxylase.

Mockus SM, Vrana KE.

J Mol Neurosci. 1998 Jun;10(3):163-79. Review.

PMID:
9770640
[PubMed - indexed for MEDLINE]
15.

Amino-terminal analysis of tryptophan hydroxylase: protein kinase phosphorylation occurs at serine-58.

Kumer SC, Mockus SM, Rucker PJ, Vrana KE.

J Neurochem. 1997 Oct;69(4):1738-45.

PMID:
9326303
[PubMed - indexed for MEDLINE]
16.

Expression and deletion mutagenesis of tryptophan hydroxylase fusion proteins: delineation of the enzyme catalytic core.

D'Sa CM, Arthur RE Jr, Kuhn DM.

J Neurochem. 1996 Sep;67(3):917-26.

PMID:
8752096
[PubMed - indexed for MEDLINE]
17.

Phosphorylation and activation of tryptophan hydroxylase 2: identification of serine-19 as the substrate site for calcium, calmodulin-dependent protein kinase II.

Kuhn DM, Sakowski SA, Geddes TJ, Wilkerson C, Haycock JW.

J Neurochem. 2007 Nov;103(4):1567-73. Epub 2007 Aug 28.

PMID:
17727633
[PubMed - indexed for MEDLINE]
18.

Mouse tryptophan hydroxylase isoform 2 and the role of proline 447 in enzyme function.

Sakowski SA, Geddes TJ, Kuhn DM.

J Neurochem. 2006 Feb;96(3):758-65. Epub 2006 Jan 9.

PMID:
16405505
[PubMed - indexed for MEDLINE]
19.

Characterization of a stable form of tryptophan hydroxylase from the human parasite Schistosoma mansoni.

Hamdan FF, Ribeiro P.

J Biol Chem. 1999 Jul 30;274(31):21746-54.

PMID:
10419488
[PubMed - indexed for MEDLINE]
Free Article
20.

Tyrosine hydroxylase and tryptophan hydroxylase do not form heterotetramers.

Mockus SM, Yohrling GJ 4th, Vrana KE.

J Mol Neurosci. 1998 Feb;10(1):45-51.

PMID:
9589369
[PubMed - indexed for MEDLINE]

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