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Results: 1 to 20 of 986

1.

Identification of phenacetin metabolites in human urine after administration of phenacetin-C2H3: measurement of futile metabolic deacetylation via HPLC/MS-SPE-NMR and HPLC-ToF MS.

Nicholls AW, Wilson ID, Godejohann M, Nicholson JK, Shockcor JP.

Xenobiotica. 2006 Jul;36(7):615-29.

PMID:
16864507
[PubMed - indexed for MEDLINE]
2.

Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat.

Nicholls AW, Lindon JC, Farrant RD, Shockcor JP, Wilson ID, Nicholson JK.

J Pharm Biomed Anal. 1999 Sep;20(6):865-73.

PMID:
10746955
[PubMed - indexed for MEDLINE]
3.

NMR and HPLC-NMR spectroscopic studies of futile deacetylation in paracetamol metabolites in rat and man.

Nicholls AW, Farrant RD, Shockcor JP, Unger SE, Wilson ID, Lindon JC, Nicholson JK.

J Pharm Biomed Anal. 1997 Apr;15(7):901-10.

PMID:
9160256
[PubMed - indexed for MEDLINE]
4.

NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat.

Nicholls AW, Lindon JC, Caddick S, Farrant RD, Wilson ID, Nicholson JK.

Xenobiotica. 1997 Nov;27(11):1175-86.

PMID:
9413921
[PubMed - indexed for MEDLINE]
5.

High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat.

Nicholls AW, Caddick S, Wilson ID, Farrant RD, Lindon JC, Nicholson JK.

Biochem Pharmacol. 1995 Apr 18;49(8):1155-64.

PMID:
7748197
[PubMed - indexed for MEDLINE]
6.

HPLC-NMR with severe column overloading: fast-track metabolite identification in urine and bile samples from rat and dog treated with [14C]-ZD6126.

Lenz EM, D'Souza RA, Jordan AC, King CD, Smith SM, Phillips PJ, McCormick AD, Roberts DW.

J Pharm Biomed Anal. 2007 Feb 19;43(3):1065-77. Epub 2006 Oct 9.

PMID:
17030109
[PubMed - indexed for MEDLINE]
7.

Investigation of the metabolism of 14C/13C-practolol in rat using directly coupled radio-HPLC-NMR-MS.

Scarfe GB, Lindon JC, Nicholson JK, Martin P, Wright B, Taylor S, Lenz E, Wilson ID.

Xenobiotica. 2000 Jul;30(7):717-29.

PMID:
10963062
[PubMed - indexed for MEDLINE]
8.
9.

Identification of the urinary metabolites of 4-bromoaniline and 4-bromo-[carbonyl-13C]-acetanilide in rat.

Scarfe GB, Nicholson JK, Lindon JC, Wilson ID, Taylor S, Clayton E, Wright B.

Xenobiotica. 2002 Apr;32(4):325-37.

PMID:
12028665
[PubMed - indexed for MEDLINE]
10.

Metabolism of 3-chloro-4-fluoroaniline in rat using [14C]-radiolabelling, 19F-NMR spectroscopy, HPLC-MS/MS, HPLC-ICPMS and HPLC-NMR.

Duckett CJ, Lindon JC, Walker H, Abou-Shakra F, Wilson ID, Nicholson JK.

Xenobiotica. 2006 Jan;36(1):59-77.

PMID:
16507513
[PubMed - indexed for MEDLINE]
11.
12.

Comprehensive non-targeted analysis of contaminated groundwater of a former ammunition destruction site using 1H-NMR and HPLC-SPE-NMR/TOF-MS.

Godejohann M, Heintz L, Daolio C, Berset JD, Muff D.

Environ Sci Technol. 2009 Sep 15;43(18):7055-61.

PMID:
19806741
[PubMed - indexed for MEDLINE]
13.

Combined HPLC, NMR spectroscopy, and ion-trap mass spectrometry with application to the detection and characterization of xenobiotic and endogenous metabolites in human urine.

Shockcor JP, Unger SE, Wilson ID, Foxall PJ, Nicholson JK, Lindon JC.

Anal Chem. 1996 Dec 15;68(24):4431-5.

PMID:
8972626
[PubMed - indexed for MEDLINE]
14.

Liquid chromatography/nuclear magnetic resonance spectroscopy and liquid chromatography/mass spectrometry identification of novel metabolites of the multidrug resistance modulator LY335979 in rat bile and human liver microsomal incubations.

Ehlhardt WJ, Woodland JM, Baughman TM, Vandenbranden M, Wrighton SA, Kroin JS, Norman BH, Maple SR.

Drug Metab Dispos. 1998 Jan;26(1):42-51.

PMID:
9443851
[PubMed - indexed for MEDLINE]
Free Article
15.

Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen.

Sidelmann UG, Bjørnsdottir I, Shockcor JP, Hansen SH, Lindon JC, Nicholson JK.

J Pharm Biomed Anal. 2001 Feb;24(4):569-79.

PMID:
11272313
[PubMed - indexed for MEDLINE]
17.

Purification and 1H NMR spectroscopic characterization of phase II metabolites of tolfenamic acid.

Sidelmann UG, Christiansen E, Krogh L, Cornett C, Tjørnelund J, Hansen SH.

Drug Metab Dispos. 1997 Jun;25(6):725-31.

PMID:
9193874
[PubMed - indexed for MEDLINE]
Free Article
18.

Evaluation of liquid chromatography coupled with high-field 1H NMR spectroscopy for drug metabolite detection and characterization: the identification of paracetamol metabolites in urine and bile.

Spraul M, Hofmann M, Lindon JC, Farrant RD, Seddon MJ, Nicholson JK, Wilson ID.

NMR Biomed. 1994 Nov;7(7):295-303.

PMID:
7718429
[PubMed - indexed for MEDLINE]
19.

Cyclosporin A-induced changes in endogenous metabolites in rat urine: a metabonomic investigation using high field 1H NMR spectroscopy, HPLC-TOF/MS and chemometrics.

Lenz EM, Bright J, Knight R, Wilson ID, Major H.

J Pharm Biomed Anal. 2004 May 28;35(3):599-608.

PMID:
15137985
[PubMed - indexed for MEDLINE]
20.

Mass spectrometrically detected directly coupled high performance liquid chromatography/nuclear magnetic resonance spectroscopy/mass spectrometry for the identification of xenobiotic metabolites in maize plants.

Bailey NJ, Stanley PD, Hadfield ST, Lindon JC, Nicholson JK.

Rapid Commun Mass Spectrom. 2000;14(8):679-84.

PMID:
10786907
[PubMed - indexed for MEDLINE]

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