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Items: 1 to 20 of 92

1.

Structural properties of the NMDA receptor and the design of neuroprotective therapies.

Gerber AM, Vallano ML.

Mini Rev Med Chem. 2006 Jul;6(7):805-15. Review.

PMID:
16842130
2.
3.

NMDA/NR2B selective antagonists in the treatment of ischemic brain injury.

Wang CX, Shuaib A.

Curr Drug Targets CNS Neurol Disord. 2005 Apr;4(2):143-51. Review.

PMID:
15857299
4.

Adenosine A2A receptor antagonism and neuroprotection: mechanisms, lights, and shadows.

Popoli P, Minghetti L, Tebano MT, Pintor A, Domenici MR, Massotti M.

Crit Rev Neurobiol. 2004;16(1-2):99-106. Review.

PMID:
15581405
5.

Paradigm shift in neuroprotective drug development: clinically tolerated NMDA receptor inhibition by memantine.

Lipton SA, Chen HS.

Cell Death Differ. 2004 Jan;11(1):18-20. No abstract available.

6.

3-Nitropropionic acid toxicity in hippocampus: protection through N-methyl-D-aspartate receptor antagonism.

Karanian DA, Baude AS, Brown QB, Parsons CG, Bahr BA.

Hippocampus. 2006;16(10):834-42.

PMID:
16897723
7.

Computer simulation of the three-dimensional structure of the glutamate site of the NR2B subunit of the NMDA receptor.

Tikhonova IG, Baskin II, Palyulin VA, Zefirov NS.

Dokl Biochem Biophys. 2002 Jan-Feb;382:38-41. No abstract available.

PMID:
11938667
8.

Neuroprotection by tosyl-polyamine derivatives through the inhibition of ionotropic glutamate receptors.

Masuko T, Namiki R, Nemoto Y, Miyake M, Kizawa Y, Suzuki T, Kashiwagi K, Igarashi K, Kusama T.

J Pharmacol Exp Ther. 2009 Nov;331(2):522-30. doi: 10.1124/jpet.109.152926. Epub 2009 Jul 30.

9.

Competitive AMPA receptor antagonists.

Catarzi D, Colotta V, Varano F.

Med Res Rev. 2007 Mar;27(2):239-78. Review.

PMID:
16892196
10.

GMP prevents excitotoxicity mediated by NMDA receptor activation but not by reversal activity of glutamate transporters in rat hippocampal slices.

Molz S, Tharine DC, Decker H, Tasca CI.

Brain Res. 2008 Sep 22;1231:113-20. doi: 10.1016/j.brainres.2008.07.009. Epub 2008 Jul 11.

PMID:
18655777
11.

Synergistic neuroprotection by bis(7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase.

Li W, Xue J, Niu C, Fu H, Lam CS, Luo J, Chan HH, Xue H, Kan KK, Lee NT, Li C, Pang Y, Li M, Tsim KW, Jiang H, Chen K, Li X, Han Y.

Mol Pharmacol. 2007 May;71(5):1258-67. Epub 2007 Feb 13.

12.

Resistance to kynurenic acid of the NMDA receptor-dependent toxicity of 3-nitropropionic acid and cyanide in cerebellar granule neurons.

Fatokun AA, Smith RA, Stone TW.

Brain Res. 2008 Jun 18;1215:200-7. doi: 10.1016/j.brainres.2008.04.013. Epub 2008 Apr 16.

PMID:
18486115
13.

Structural basis of NR2B-selective antagonist recognition by N-methyl-D-aspartate receptors.

Mony L, Krzaczkowski L, Leonetti M, Le Goff A, Alarcon K, Neyton J, Bertrand HO, Acher F, Paoletti P.

Mol Pharmacol. 2009 Jan;75(1):60-74. doi: 10.1124/mol.108.050971. Epub 2008 Oct 15.

14.

On the hypes and falls in neuroprotection: targeting the NMDA receptor.

Villmann C, Becker CM.

Neuroscientist. 2007 Dec;13(6):594-615. Epub 2007 Oct 2. Review.

PMID:
17911221
15.

Inhibition of Calpain Prevents N-Methyl-D-aspartate-Induced Degeneration of the Nucleus Basalis and Associated Behavioral Dysfunction.

Nimmrich V, Szabo R, Nyakas C, Granic I, Reymann KG, Schröder UH, Gross G, Schoemaker H, Wicke K, Möller A, Luiten P.

J Pharmacol Exp Ther. 2008 Nov;327(2):343-52. doi: 10.1124/jpet.108.142679. Epub 2008 Aug 13.

16.

NR1 and GluR2 expression mediates excitotoxicity in chronic hypobaric hypoxia.

Hota SK, Barhwal K, Singh SB, Sairam M, Ilavazhagan G.

J Neurosci Res. 2008 Apr;86(5):1142-52.

PMID:
17969105
17.

In vitro galantamine-memantine co-application: mechanism of beneficial action.

Zhao X, Marszalec W, Toth PT, Huang J, Yeh JZ, Narahashi T.

Neuropharmacology. 2006 Dec;51(7-8):1181-91. Epub 2006 Sep 29.

PMID:
17011596
18.

Neuroprotective cannabinoid receptor antagonist SR141716A prevents downregulation of excitotoxic NMDA receptors in the ischemic penumbra.

Sommer C, Schomacher M, Berger C, Kuhnert K, Müller HD, Schwab S, Schäbitz WR.

Acta Neuropathol. 2006 Sep;112(3):277-86. Epub 2006 Jul 27.

PMID:
16871404
19.

NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo.

Liu Y, Wong TP, Aarts M, Rooyakkers A, Liu L, Lai TW, Wu DC, Lu J, Tymianski M, Craig AM, Wang YT.

J Neurosci. 2007 Mar 14;27(11):2846-57.

20.

Phosphorylation of neurofilament subunit NF-M is regulated by activation of NMDA receptors and modulates cytoskeleton stability and neuronal shape.

Fiumelli H, Riederer IM, Martin JL, Riederer BM.

Cell Motil Cytoskeleton. 2008 Jun;65(6):495-504. doi: 10.1002/cm.20278.

PMID:
18412220
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