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Results: 1 to 20 of 83

1.

Disabled-2 heterozygous mice are predisposed to endometrial and ovarian tumorigenesis and exhibit sex-biased embryonic lethality in a p53-null background.

Yang DH, Fazili Z, Smith ER, Cai KQ, Klein-Szanto A, Cohen C, Horowitz IR, Xu XX.

Am J Pathol. 2006 Jul;169(1):258-67.

PMID:
16816378
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Disabled-2 inactivation is an early step in ovarian tumorigenicity.

Fazili Z, Sun W, Mittelstaedt S, Cohen C, Xu XX.

Oncogene. 1999 May 20;18(20):3104-13.

PMID:
10340382
[PubMed - indexed for MEDLINE]
Free Article
3.

Molecular events associated with dysplastic morphologic transformation and initiation of ovarian tumorigenicity.

Yang DH, Smith ER, Cohen C, Wu H, Patriotis C, Godwin AK, Hamilton TC, Xu XX.

Cancer. 2002 May 1;94(9):2380-92.

PMID:
12015763
[PubMed - indexed for MEDLINE]
Free Article
4.

Loss of surface and cyst epithelial basement membranes and preneoplastic morphologic changes in prophylactic oophorectomies.

Roland IH, Yang WL, Yang DH, Daly MB, Ozols RF, Hamilton TC, Lynch HT, Godwin AK, Xu XX.

Cancer. 2003 Dec 15;98(12):2607-23.

PMID:
14669280
[PubMed - indexed for MEDLINE]
Free Article
5.

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

Yang DH, Smith ER, Roland IH, Sheng Z, He J, Martin WD, Hamilton TC, Lambeth JD, Xu XX.

Dev Biol. 2002 Nov 1;251(1):27-44.

PMID:
12413896
[PubMed - indexed for MEDLINE]
6.

Dynamic alterations of the extracellular environment of ovarian surface epithelial cells in premalignant transformation, tumorigenicity, and metastasis.

Capo-Chichi CD, Smith ER, Yang DH, Roland IH, Vanderveer L, Cohen C, Hamilton TC, Godwin AK, Xu XX.

Cancer. 2002 Oct 15;95(8):1802-15.

PMID:
12365030
[PubMed - indexed for MEDLINE]
Free Article
7.

Restoration of positioning control following Disabled-2 expression in ovarian and breast tumor cells.

Sheng Z, Sun W, Smith E, Cohen C, Sheng Z, Xu XX.

Oncogene. 2000 Oct 5;19(42):4847-54.

PMID:
11039902
[PubMed - indexed for MEDLINE]
Free Article
8.

Differential requirement for Dab2 in the development of embryonic and extra-embryonic tissues.

Moore R, Cai KQ, Tao W, Smith ER, Xu XX.

BMC Dev Biol. 2013 Oct 29;13:39. doi: 10.1186/1471-213X-13-39.

PMID:
24168030
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Alterations of the p53 tumor suppressor gene and its association with activation of the c-K-ras-2 protooncogene in premalignant and malignant lesions of the human uterine endometrium.

Enomoto T, Fujita M, Inoue M, Rice JM, Nakajima R, Tanizawa O, Nomura T.

Cancer Res. 1993 Apr 15;53(8):1883-8.

PMID:
8385572
[PubMed - indexed for MEDLINE]
Free Article
10.

Disabled-2 is required for mesoderm differentiation of murine embryonic stem cells.

Huang CL, Cheng JC, Kitajima K, Nakano T, Yeh CF, Chong KY, Tseng CP.

J Cell Physiol. 2010 Oct;225(1):92-105. doi: 10.1002/jcp.22200.

PMID:
20648627
[PubMed - indexed for MEDLINE]
11.

Disabled-2 is an epithelial surface positioning gene.

Yang DH, Cai KQ, Roland IH, Smith ER, Xu XX.

J Biol Chem. 2007 Apr 27;282(17):13114-22. Epub 2007 Mar 5.

PMID:
17339320
[PubMed - indexed for MEDLINE]
Free Article
12.

C-Fos elimination compensates for disabled-2 requirement in mouse extraembryonic endoderm development.

Yang DH, Smith ER, Cai KQ, Xu XX.

Dev Dyn. 2009 Mar;238(3):514-23. doi: 10.1002/dvdy.21856.

PMID:
19191218
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy.

Clarke AR, Cummings MC, Harrison DJ.

Oncogene. 1995 Nov 2;11(9):1913-20.

PMID:
7478622
[PubMed - indexed for MEDLINE]
14.

Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT).

Prunier C, Howe PH.

J Biol Chem. 2005 Apr 29;280(17):17540-8. Epub 2005 Feb 25.

PMID:
15734730
[PubMed - indexed for MEDLINE]
Free Article
15.

The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm.

Morrisey EE, Musco S, Chen MY, Lu MM, Leiden JM, Parmacek MS.

J Biol Chem. 2000 Jun 30;275(26):19949-54.

PMID:
10779506
[PubMed - indexed for MEDLINE]
Free Article
16.

Cell autonomous sorting and surface positioning in the formation of primitive endoderm in embryoid bodies.

Rula ME, Cai KQ, Moore R, Yang DH, Staub CM, Capo-Chichi CD, Jablonski SA, Howe PH, Smith ER, Xu XX.

Genesis. 2007 Jun;45(6):327-38.

PMID:
17506089
[PubMed - indexed for MEDLINE]
17.

Disabled-2 mediates c-Fos suppression and the cell growth regulatory activity of retinoic acid in embryonic carcinoma cells.

Smith ER, Capo-chichi CD, He J, Smedberg JL, Yang DH, Prowse AH, Godwin AK, Hamilton TC, Xu XX.

J Biol Chem. 2001 Dec 14;276(50):47303-10. Epub 2001 Sep 27.

PMID:
11577091
[PubMed - indexed for MEDLINE]
Free Article
18.

Dynamic expression of Dab2 in the mouse embryonic central nervous system.

Cheung KK, Mok SC, Rezaie P, Chan WY.

BMC Dev Biol. 2008 Aug 4;8:76. doi: 10.1186/1471-213X-8-76.

PMID:
18680569
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Disabled-2 exerts its tumor suppressor activity by uncoupling c-Fos expression and MAP kinase activation.

He J, Smith ER, Xu XX.

J Biol Chem. 2001 Jul 20;276(29):26814-8. Epub 2001 May 18.

PMID:
11359772
[PubMed - indexed for MEDLINE]
Free Article
20.

Decreased DOC-2/DAB2 expression in urothelial carcinoma of the bladder.

Karam JA, Shariat SF, Huang HY, Pong RC, Ashfaq R, Shapiro E, Lotan Y, Sagalowsky AI, Wu XR, Hsieh JT.

Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4400-6.

PMID:
17671122
[PubMed - indexed for MEDLINE]
Free Article
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