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Results: 1 to 20 of 103

1.

Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells.

White PM, Doetzlhofer A, Lee YS, Groves AK, Segil N.

Nature. 2006 Jun 22;441(7096):984-7.

PMID:
16791196
[PubMed - indexed for MEDLINE]
2.

Development and regeneration of the inner ear.

Kwan T, White PM, Segil N.

Ann N Y Acad Sci. 2009 Jul;1170:28-33. doi: 10.1111/j.1749-6632.2009.04484.x. Review.

PMID:
19686102
[PubMed - indexed for MEDLINE]
3.

EGFR signaling is required for regenerative proliferation in the cochlea: conservation in birds and mammals.

White PM, Stone JS, Groves AK, Segil N.

Dev Biol. 2012 Mar 1;363(1):191-200. doi: 10.1016/j.ydbio.2011.12.035. Epub 2012 Jan 2.

PMID:
22230616
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti.

Chen P, Segil N.

Development. 1999 Apr;126(8):1581-90.

PMID:
10079221
[PubMed - indexed for MEDLINE]
Free Article
5.

Prospective identification and purification of hair cell and supporting cell progenitors from the embryonic cochlea.

Doetzlhofer A, White P, Lee YS, Groves A, Segil N.

Brain Res. 2006 May 26;1091(1):282-8. Epub 2006 Apr 17.

PMID:
16616734
[PubMed - indexed for MEDLINE]
6.

Expression of candidate markers for stem/progenitor cells in the inner ears of developing and adult GFAP and nestin promoter-GFP transgenic mice.

Smeti I, Savary E, Capelle V, Hugnot JP, Uziel A, Zine A.

Gene Expr Patterns. 2011 Jan-Feb;11(1-2):22-32. doi: 10.1016/j.gep.2010.08.008. Epub 2010 Sep 9.

PMID:
20817025
[PubMed - indexed for MEDLINE]
7.

Silencing p27 reverses post-mitotic state of supporting cells in neonatal mouse cochleae.

Ono K, Nakagawa T, Kojima K, Matsumoto M, Kawauchi T, Hoshino M, Ito J.

Mol Cell Neurosci. 2009 Dec;42(4):391-8. doi: 10.1016/j.mcn.2009.08.011. Epub 2009 Sep 4.

PMID:
19733668
[PubMed - indexed for MEDLINE]
8.

Concise review: Inner ear stem cells--an oxymoron, but why?

Ronaghi M, Nasr M, Heller S.

Stem Cells. 2012 Jan;30(1):69-74. doi: 10.1002/stem.785. Review.

PMID:
22102534
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti.

Löwenheim H, Furness DN, Kil J, Zinn C, Gültig K, Fero ML, Frost D, Gummer AW, Roberts JM, Rubel EW, Hackney CM, Zenner HP.

Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):4084-8.

PMID:
10097167
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

[Regeneration of ciliated cells in the internal ear].

Lefèbvre P.

Bull Mem Acad R Med Belg. 2002;157(5-6):251-8; discussion 258-60. French.

PMID:
12557571
[PubMed - indexed for MEDLINE]
11.

Cell cycle regulation in the inner ear sensory epithelia: role of cyclin D1 and cyclin-dependent kinase inhibitors.

Laine H, Sulg M, Kirjavainen A, Pirvola U.

Dev Biol. 2010 Jan 1;337(1):134-46. doi: 10.1016/j.ydbio.2009.10.027. Epub 2009 Oct 23.

PMID:
19854167
[PubMed - indexed for MEDLINE]
Free Article
12.

Regulation of p27Kip1 by Sox2 maintains quiescence of inner pillar cells in the murine auditory sensory epithelium.

Liu Z, Walters BJ, Owen T, Brimble MA, Steigelman KA, Zhang L, Mellado Lagarde MM, Valentine MB, Yu Y, Cox BC, Zuo J.

J Neurosci. 2012 Aug 1;32(31):10530-40. doi: 10.1523/JNEUROSCI.0686-12.2012.

PMID:
22855803
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

p27Kip1 knockdown induces proliferation in the organ of Corti in culture after efficient shRNA lentiviral transduction.

Maass JC, Berndt FA, Cánovas J, Kukuljan M.

J Assoc Res Otolaryngol. 2013 Aug;14(4):495-508. doi: 10.1007/s10162-013-0383-2. Epub 2013 Apr 24.

PMID:
23612739
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Localization and developmental expression of BK channels in mammalian cochlear hair cells.

Hafidi A, Beurg M, Dulon D.

Neuroscience. 2005;130(2):475-84.

PMID:
15664704
[PubMed - indexed for MEDLINE]
15.

p27(Kip1) deficiency causes organ of Corti pathology and hearing loss.

Kanzaki S, Beyer LA, Swiderski DL, Izumikawa M, Stöver T, Kawamoto K, Raphael Y.

Hear Res. 2006 Apr;214(1-2):28-36. Epub 2006 Mar 2.

PMID:
16513305
[PubMed - indexed for MEDLINE]
16.

PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice.

Sun C, Zhao J, Jin Y, Hou C, Zong W, Lu T, Li H, Gao J.

Neuroreport. 2014 Feb 12;25(3):177-83. doi: 10.1097/WNR.0000000000000069.

PMID:
24481416
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d.

Chen P, Zindy F, Abdala C, Liu F, Li X, Roussel MF, Segil N.

Nat Cell Biol. 2003 May;5(5):422-6.

PMID:
12717441
[PubMed - indexed for MEDLINE]
18.

The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival.

Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ.

Development. 2003 Jan;130(1):221-32.

PMID:
12441305
[PubMed - indexed for MEDLINE]
Free Article
19.

Distinct population of hair cell progenitors can be isolated from the postnatal mouse cochlea using side population analysis.

Savary E, Hugnot JP, Chassigneux Y, Travo C, Duperray C, Van De Water T, Zine A.

Stem Cells. 2007 Feb;25(2):332-9. Epub 2006 Oct 12.

PMID:
17038670
[PubMed - indexed for MEDLINE]
Free Article
20.

Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration.

Walters BJ, Zuo J.

Hear Res. 2013 Mar;297:68-83. doi: 10.1016/j.heares.2012.11.009. Epub 2012 Nov 16. Review.

PMID:
23164734
[PubMed - indexed for MEDLINE]
Free PMC Article
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