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Items: 1 to 20 of 102

1.

Borrelia burgdorferi Induces TLR1 and TLR2 in human microglia and peripheral blood monocytes but differentially regulates HLA-class II expression.

Cassiani-Ingoni R, Cabral ES, Lünemann JD, Garza Z, Magnus T, Gelderblom H, Munson PJ, Marques A, Martin R.

J Neuropathol Exp Neurol. 2006 Jun;65(6):540-8.

2.

Toll-like receptors: insights into their possible role in the pathogenesis of lyme neuroborreliosis.

Bernardino AL, Myers TA, Alvarez X, Hasegawa A, Philipp MT.

Infect Immun. 2008 Oct;76(10):4385-95. doi: 10.1128/IAI.00394-08. Epub 2008 Aug 11.

3.

Borrelia burgdorferi lipoprotein-mediated TLR2 stimulation causes the down-regulation of TLR5 in human monocytes.

Cabral ES, Gelderblom H, Hornung RL, Munson PJ, Martin R, Marques AR.

J Infect Dis. 2006 Mar 15;193(6):849-59. Epub 2006 Feb 8.

4.

Toll-like receptors 1 and 2 heterodimers alter Borrelia burgdorferi gene expression in mice and ticks.

Fikrig E, Narasimhan S, Neelakanta G, Pal U, Chen M, Flavell R.

J Infect Dis. 2009 Oct 15;200(8):1331-40. doi: 10.1086/605950.

5.

Activation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-beta.

Salazar JC, Duhnam-Ems S, La Vake C, Cruz AR, Moore MW, Caimano MJ, Velez-Climent L, Shupe J, Krueger W, Radolf JD.

PLoS Pathog. 2009 May;5(5):e1000444. doi: 10.1371/journal.ppat.1000444. Epub 2009 May 22.

6.

TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetes.

Oosting M, Ter Hofstede H, Sturm P, Adema GJ, Kullberg BJ, van der Meer JW, Netea MG, Joosten LA.

PLoS One. 2011;6(10):e25998. doi: 10.1371/journal.pone.0025998. Epub 2011 Oct 5.

7.

Live Borrelia burgdorferi spirochetes elicit inflammatory mediators from human monocytes via the Toll-like receptor signaling pathway.

Dennis VA, Dixit S, O'Brien SM, Alvarez X, Pahar B, Philipp MT.

Infect Immun. 2009 Mar;77(3):1238-45. doi: 10.1128/IAI.01078-08. Epub 2009 Jan 12.

8.

Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta.

Cervantes JL, Dunham-Ems SM, La Vake CJ, Petzke MM, Sahay B, Sellati TJ, Radolf JD, Salazar JC.

Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3683-8. doi: 10.1073/pnas.1013776108. Epub 2011 Feb 14.

9.

Microglia are mediators of Borrelia burgdorferi-induced apoptosis in SH-SY5Y neuronal cells.

Myers TA, Kaushal D, Philipp MT.

PLoS Pathog. 2009 Nov;5(11):e1000659. doi: 10.1371/journal.ppat.1000659. Epub 2009 Nov 13.

10.

Interaction of the Lyme disease spirochete Borrelia burgdorferi with brain parenchyma elicits inflammatory mediators from glial cells as well as glial and neuronal apoptosis.

Ramesh G, Borda JT, Dufour J, Kaushal D, Ramamoorthy R, Lackner AA, Philipp MT.

Am J Pathol. 2008 Nov;173(5):1415-27. doi: 10.2353/ajpath.2008.080483. Epub 2008 Oct 2.

11.

Differential responses between monocytes and monocyte-derived macrophages for lipopolysaccharide stimulation of calves.

Guo Y, Zhao G, Tanaka S, Yamaguchi T.

Cell Mol Immunol. 2009 Jun;6(3):223-9. doi: 10.1038/cmi.2009.30.

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14.

Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins.

Chang S, Dolganiuc A, Szabo G.

J Leukoc Biol. 2007 Sep;82(3):479-87. Epub 2007 Jun 26.

15.

Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis.

Miklossy J, Kasas S, Zurn AD, McCall S, Yu S, McGeer PL.

J Neuroinflammation. 2008 Sep 25;5:40. doi: 10.1186/1742-2094-5-40.

16.

Opposing effects of Toll-like receptors 2 and 4 on synaptic stability in the spinal cord after peripheral nerve injury.

Freria CM, Velloso LA, Oliveira AL.

J Neuroinflammation. 2012 Oct 23;9:240. doi: 10.1186/1742-2094-9-240.

17.

Phagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, potentiates innate immune activation and induces apoptosis in human monocytes.

Cruz AR, Moore MW, La Vake CJ, Eggers CH, Salazar JC, Radolf JD.

Infect Immun. 2008 Jan;76(1):56-70. Epub 2007 Oct 15.

18.

Borrelia burgdorferi RNA induces type I and III interferons via Toll-like receptor 7 and contributes to production of NF-κB-dependent cytokines.

Love AC, Schwartz I, Petzke MM.

Infect Immun. 2014 Jun;82(6):2405-16. doi: 10.1128/IAI.01617-14. Epub 2014 Mar 24.

19.

Generation and characterization of immortalized human microglial cell lines: expression of cytokines and chemokines.

Nagai A, Nakagawa E, Hatori K, Choi HB, McLarnon JG, Lee MA, Kim SU.

Neurobiol Dis. 2001 Dec;8(6):1057-68.

PMID:
11741401
20.

Borrelia burgdorferi induces inflammatory mediator production by murine microglia.

Rasley A, Anguita J, Marriott I.

J Neuroimmunol. 2002 Sep;130(1-2):22-31.

PMID:
12225885
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