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Results: 1 to 20 of 88

1.

ACAT inhibition and the progression of coronary atherosclerosis.

Rudel LL, Farese RV Jr.

N Engl J Med. 2006 Jun 15;354(24):2616-7; author reply 2616-7. No abstract available.

PMID:
16775245
[PubMed - indexed for MEDLINE]
Free Article
2.

Failure of ACAT inhibition to retard atherosclerosis.

Fazio S, Linton M.

N Engl J Med. 2006 Mar 23;354(12):1307-9. No abstract available.

PMID:
16554534
[PubMed - indexed for MEDLINE]
3.

Effect of ACAT inhibition on the progression of coronary atherosclerosis.

Nissen SE, Tuzcu EM, Brewer HB, Sipahi I, Nicholls SJ, Ganz P, Schoenhagen P, Waters DD, Pepine CJ, Crowe TD, Davidson MH, Deanfield JE, Wisniewski LM, Hanyok JJ, Kassalow LM; ACAT Intravascular Atherosclerosis Treatment Evaluation (ACTIVATE) Investigators.

N Engl J Med. 2006 Mar 23;354(12):1253-63. Erratum in: N Engl J Med. 2006 Aug 10;355(6):638.

PMID:
16554527
[PubMed - indexed for MEDLINE]
Free Article
4.

Intravascular ultrasound assessment of novel antiatherosclerotic therapies: rationale and design of the Acyl-CoA:Cholesterol Acyltransferase Intravascular Atherosclerosis Treatment Evaluation (ACTIVATE) Study.

Nicholls SJ, Sipahi I, Schoenhagen P, Wisniewski L, Churchill T, Crowe T, Goormastic M, Wolski K, Tuzcu EM, Nissen SE; ACTIVATE Investigators.

Am Heart J. 2006 Jul;152(1):67-74.

PMID:
16824833
[PubMed - indexed for MEDLINE]
5.

Carotid atherosclerosis progression and ACAT inhibition.

Parini P, Eriksson M, Rudel LL.

JAMA. 2009 Jul 15;302(3):255; author reply 256-7. doi: 10.1001/jama.2009.1000. No abstract available.

PMID:
19602681
[PubMed - indexed for MEDLINE]
6.

[New agents against atherosclerosis tested. Alarming findings, ACAT inhibitors seem to have proatherogenic effects].

Wiklund O.

Lakartidningen. 2006 Oct 25-31;103(43):3270. Swedish. No abstract available.

PMID:
17117657
[PubMed - indexed for MEDLINE]
7.

ACAT inhibition and progression of carotid atherosclerosis in patients with familial hypercholesterolemia: the CAPTIVATE randomized trial.

Meuwese MC, de Groot E, Duivenvoorden R, Trip MD, Ose L, Maritz FJ, Basart DC, Kastelein JJ, Habib R, Davidson MH, Zwinderman AH, Schwocho LR, Stein EA; CAPTIVATE Investigators.

JAMA. 2009 Mar 18;301(11):1131-9. doi: 10.1001/jama.301.11.1131.

PMID:
19293413
[PubMed - indexed for MEDLINE]
8.

Atherosclerosis drug fails to meet Phase III trial end point.

[No authors listed]

Nat Rev Drug Discov. 2009 May;8(5):348. doi: 10.1038/nrd2879. No abstract available.

PMID:
19404306
[PubMed - indexed for MEDLINE]
9.

Effects of the acyl coenzyme A:cholesterol acyltransferase inhibitor avasimibe on human atherosclerotic lesions.

Tardif JC, Grégoire J, L'Allier PL, Anderson TJ, Bertrand O, Reeves F, Title LM, Alfonso F, Schampaert E, Hassan A, McLain R, Pressler ML, Ibrahim R, Lespérance J, Blue J, Heinonen T, Rodés-Cabau J; Avasimibe and Progression of Lesions on UltraSound (A-PLUS) Investigators.

Circulation. 2004 Nov 23;110(21):3372-7. Epub 2004 Nov 8.

PMID:
15533865
[PubMed - indexed for MEDLINE]
Free Article
10.

Pactimibe stabilizes atherosclerotic plaque through macrophage acyl-CoA:cholesterol acyltransferase inhibition in WHHL rabbits.

Kitayama K, Koga T, Maeda N, Inaba T, Fujioka T.

Eur J Pharmacol. 2006 Jun 6;539(1-2):81-8. Epub 2006 Apr 7.

PMID:
16690054
[PubMed - indexed for MEDLINE]
11.

Can we cause regression of coronary atherosclerosis?

Alsafwah S, Ramanathan KB.

Am J Med Sci. 2008 May;335(5):368-74. doi: 10.1097/MAJ.0b013e31815c3b32.

PMID:
18480653
[PubMed - indexed for MEDLINE]
12.

Acyl coenzyme A:cholesterol acyltransferase inhibition: potential atherosclerosis therapy or springboard for other discoveries?

Heinonen TM.

Expert Opin Investig Drugs. 2002 Nov;11(11):1519-27. Review.

PMID:
12437499
[PubMed - indexed for MEDLINE]
13.

ACAT inhibitor pactimibe sulfate (CS-505) reduces and stabilizes atherosclerotic lesions by cholesterol-lowering and direct effects in apolipoprotein E-deficient mice.

Terasaka N, Miyazaki A, Kasanuki N, Ito K, Ubukata N, Koieyama T, Kitayama K, Tanimoto T, Maeda N, Inaba T.

Atherosclerosis. 2007 Feb;190(2):239-47. Epub 2006 Apr 19.

PMID:
16626720
[PubMed - indexed for MEDLINE]
14.

Eflucimibe. Pierre Fabre/Eli Lilly.

Burnett JR.

Curr Opin Investig Drugs. 2003 Mar;4(3):347-51. Review.

PMID:
12735237
[PubMed - indexed for MEDLINE]
15.

Carotid atherosclerosis progression and ACAT inhibition.

Dimmitt S, Watts G.

JAMA. 2009 Jul 15;302(3):255-6; author reply 256-7. doi: 10.1001/jama.2009.1001. No abstract available.

PMID:
19602680
[PubMed - indexed for MEDLINE]
16.

Inhibition of acyl coenzyme A-cholesterol acyltransferase: a possible treatment of atherosclerosis?

Heinonen TM.

Curr Atheroscler Rep. 2002 Jan;4(1):65-70. Review.

PMID:
11772425
[PubMed - indexed for MEDLINE]
17.

Comparison of intravascular ultrasound and quantitative coronary angiography for the assessment of coronary artery disease progression.

Berry C, L'Allier PL, Grégoire J, Lespérance J, Levesque S, Ibrahim R, Tardif JC.

Circulation. 2007 Apr 10;115(14):1851-7. Epub 2007 Mar 26.

PMID:
17389269
[PubMed - indexed for MEDLINE]
Free Article
18.

Human ACAT-1 and ACAT-2 inhibitory activities of pentacyclic triterpenes from the leaves of Lycopus lucidus TURCZ.

Lee WS, Im KR, Park YD, Sung ND, Jeong TS.

Biol Pharm Bull. 2006 Feb;29(2):382-4.

PMID:
16462051
[PubMed - indexed for MEDLINE]
Free Article
19.

The nine lives of ACAT inhibitors.

Farese RV Jr.

Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1684-6. Review. No abstract available.

PMID:
16857957
[PubMed - indexed for MEDLINE]
Free Article
20.

Acyl-coenzyme A:cholesterol acyltransferase inhibitors for controlling hypercholesterolemia and atherosclerosis.

Miyazaki A, Sakai M, Sakamoto Y, Horiuchi S.

Curr Opin Investig Drugs. 2003 Sep;4(9):1095-9. Review.

PMID:
14582454
[PubMed - indexed for MEDLINE]

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