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Results: 1 to 20 of 168

1.

Structural basis of substrate specificity in human glyoxylate reductase/hydroxypyruvate reductase.

Booth MP, Conners R, Rumsby G, Brady RL.

J Mol Biol. 2006 Jun 30;360(1):178-89. Epub 2006 May 22.

PMID:
16756993
[PubMed - indexed for MEDLINE]
2.

The gene encoding hydroxypyruvate reductase (GRHPR) is mutated in patients with primary hyperoxaluria type II.

Cramer SD, Ferree PM, Lin K, Milliner DS, Holmes RP.

Hum Mol Genet. 1999 Oct;8(11):2063-9. Erratum in: Hum Mol Genet 1999 Dec;8(13):2574.

PMID:
10484776
[PubMed - indexed for MEDLINE]
Free Article
3.

Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth.

Janiak V, Petersen M, Zentgraf M, Klebe G, Heine A.

Acta Crystallogr D Biol Crystallogr. 2010 May;66(Pt 5):593-603. doi: 10.1107/S0907444910006360. Epub 2010 Apr 21.

PMID:
20445235
[PubMed - indexed for MEDLINE]
4.

Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.

Genolet R, Kersten S, Braissant O, Mandard S, Tan NS, Bucher P, Desvergne B, Michalik L, Wahli W.

J Biol Chem. 2005 Jun 24;280(25):24143-52. Epub 2005 Apr 19.

PMID:
15840574
[PubMed - indexed for MEDLINE]
Free Article
5.

Molecular aetiology of primary hyperoxaluria and its implications for clinical management.

Danpure CJ, Rumsby G.

Expert Rev Mol Med. 2004 Jan 9;6(1):1-16. Review.

PMID:
14987413
[PubMed - indexed for MEDLINE]
6.

Genetic basis of primary hyperoxaluria type II.

Webster KE, Cramer SD.

Mol Urol. 2000 Winter;4(4):355-64.

PMID:
11156703
[PubMed - indexed for MEDLINE]
7.

Crystal structure of Escherichia coli ketopantoate reductase in a ternary complex with NADP+ and pantoate bound: substrate recognition, conformational change, and cooperativity.

Ciulli A, Chirgadze DY, Smith AG, Blundell TL, Abell C.

J Biol Chem. 2007 Mar 16;282(11):8487-97. Epub 2007 Jan 16.

PMID:
17229734
[PubMed - indexed for MEDLINE]
Free Article
8.

A preliminary account of the properties of recombinant human Glyoxylate reductase (GRHPR), LDHA and LDHB with glyoxylate, and their potential roles in its metabolism.

Mdluli K, Booth MP, Brady RL, Rumsby G.

Biochim Biophys Acta. 2005 Dec 1;1753(2):209-16. Epub 2005 Aug 22.

PMID:
16198644
[PubMed - indexed for MEDLINE]
Free Article
9.

Molecular analysis of the glyoxylate reductase (GRHPR) gene and description of mutations underlying primary hyperoxaluria type 2.

Cregeen DP, Williams EL, Hulton S, Rumsby G.

Hum Mutat. 2003 Dec;22(6):497.

PMID:
14635115
[PubMed - indexed for MEDLINE]
10.

NADH:hydroxypyruvate reductase and NADPH:glyoxylate reductase in algae: partial purification and characterization from Chlamydomonas reinhardtii.

Husic DW, Tolbert NE.

Arch Biochem Biophys. 1987 Feb 1;252(2):396-408.

PMID:
3545081
[PubMed - indexed for MEDLINE]
11.

Identification of catalytically important amino acid residues for enzymatic reduction of glyoxylate in plants.

Hoover GJ, Jørgensen R, Rochon A, Bajwa VS, Merrill AR, Shelp BJ.

Biochim Biophys Acta. 2013 Dec;1834(12):2663-71. doi: 10.1016/j.bbapap.2013.09.013. Epub 2013 Sep 27.

PMID:
24076009
[PubMed - indexed for MEDLINE]
12.

Crystal structure of the ternary complex of mouse lung carbonyl reductase at 1.8 A resolution: the structural origin of coenzyme specificity in the short-chain dehydrogenase/reductase family.

Tanaka N, Nonaka T, Nakanishi M, Deyashiki Y, Hara A, Mitsui Y.

Structure. 1996 Jan 15;4(1):33-45.

PMID:
8805511
[PubMed - indexed for MEDLINE]
14.

Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition.

Faucher F, Cantin L, Luu-The V, Labrie F, Breton R.

Biochemistry. 2008 Dec 23;47(51):13537-46. doi: 10.1021/bi801276h. Erratum in: Biochemistry. 2009 Feb 10;48(5):1144.

PMID:
19075558
[PubMed - indexed for MEDLINE]
15.

Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop.

Hori T, Yokomizo T, Ago H, Sugahara M, Ueno G, Yamamoto M, Kumasaka T, Shimizu T, Miyano M.

J Biol Chem. 2004 May 21;279(21):22615-23. Epub 2004 Mar 8.

PMID:
15007077
[PubMed - indexed for MEDLINE]
Free Article
16.

Recent developments in our understanding of primary hyperoxaluria type 2.

Cregeen DP, Rumsby G.

J Am Soc Nephrol. 1999 Nov;10 Suppl 14:S348-50.

PMID:
10541261
[PubMed - indexed for MEDLINE]
17.

Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site.

Alphey MS, Yu W, Byres E, Li D, Hunter WN.

J Biol Chem. 2005 Jan 28;280(4):3068-77. Epub 2004 Nov 6.

PMID:
15531764
[PubMed - indexed for MEDLINE]
Free Article
19.

Novel mutation in the GRHPR gene in a Chinese patient with primary hyperoxaluria type 2 requiring renal transplantation from a living related donor.

Lam CW, Yuen YP, Lai CK, Tong SF, Lau LK, Tong KL, Chan YW.

Am J Kidney Dis. 2001 Dec;38(6):1307-10.

PMID:
11728965
[PubMed - indexed for MEDLINE]
20.

Oxalate as a potent and selective inhibitor of spinach (Spinacia oleracea) leaf NADPH-dependent hydroxypyruvate reductase.

Kleczkowski LA, Randall DD, Edwards GE.

Biochem J. 1991 May 15;276 ( Pt 1):125-7.

PMID:
2039466
[PubMed - indexed for MEDLINE]
Free PMC Article

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