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Items: 1 to 20 of 90

1.

The Wnt-dependent signaling pathways as target in oncology drug discovery.

Janssens N, Janicot M, Perera T.

Invest New Drugs. 2006 Jul;24(4):263-80. Review.

2.

Targeting Wnt signaling: can we safely eradicate cancer stem cells?

Takahashi-Yanaga F, Kahn M.

Clin Cancer Res. 2010 Jun 15;16(12):3153-62. doi: 10.1158/1078-0432.CCR-09-2943. Epub 2010 Jun 8. Review.

3.

The Wnt/beta-catenin signaling pathway as a target in drug discovery.

Takahashi-Yanaga F, Sasaguri T.

J Pharmacol Sci. 2007 Aug;104(4):293-302. Review.

4.

WNT signalling pathways as therapeutic targets in cancer.

Anastas JN, Moon RT.

Nat Rev Cancer. 2013 Jan;13(1):11-26. doi: 10.1038/nrc3419. Review.

PMID:
23258168
5.

Small-molecule modulators of Hh and Wnt signaling pathways.

Kiselyov AS, Tkachenko SE, Balakin KV, Ivachtchenko AV.

Expert Opin Ther Targets. 2007 Aug;11(8):1087-101. Review.

PMID:
17665980
6.

Analysis of Wnt signaling during Caenorhabditis elegans postembryonic development.

Van Hoffelen S, Herman MA.

Methods Mol Biol. 2008;469:87-102. doi: 10.1007/978-1-60327-469-2_8. Review.

PMID:
19109705
7.

FAK and WNT signaling: the meeting of two pathways in cancer and development.

Fonar Y, Frank D.

Anticancer Agents Med Chem. 2011 Sep;11(7):600-6. Review.

PMID:
21707509
8.

Wnt/β-catenin/LEF-1 signaling in chronic lymphocytic leukemia (CLL): a target for current and potential therapeutic options.

Gandhirajan RK, Poll-Wolbeck SJ, Gehrke I, Kreuzer KA.

Curr Cancer Drug Targets. 2010 Nov;10(7):716-27. Review.

PMID:
20578984
9.

Wnt signaling in development, disease and translational medicine.

Coombs GS, Covey TM, Virshup DM.

Curr Drug Targets. 2008 Jul;9(7):513-31. Review.

PMID:
18673238
10.

Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach.

Chen W, Chen M, Barak LS.

Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G293-300. doi: 10.1152/ajpgi.00005.2010. Epub 2010 May 27. Review.

11.

New avenues to target Wnt/β-catenin signaling.

Verkaar F, Zaman GJ.

Drug Discov Today. 2011 Jan;16(1-2):35-41. doi: 10.1016/j.drudis.2010.11.007. Epub 2010 Nov 24. Review.

PMID:
21111060
12.

The promise and perils of Wnt signaling through beta-catenin.

Moon RT, Bowerman B, Boutros M, Perrimon N.

Science. 2002 May 31;296(5573):1644-6. Review.

PMID:
12040179
13.

Reconstruction and crosstalk of protein-protein interaction networks of Wnt and Hedgehog signaling in Drosophila melanogaster.

Toku AE, Tekir SD, Özbayraktar FB, Ülgen KÖ.

Comput Biol Chem. 2011 Oct 12;35(5):282-92. doi: 10.1016/j.compbiolchem.2011.07.002. Epub 2011 Jul 13.

PMID:
22000799
14.

Conserved mechanism of Wnt signaling function in the specification of vulval precursor fates in C. elegans and C. briggsae.

Seetharaman A, Cumbo P, Bojanala N, Gupta BP.

Dev Biol. 2010 Oct 1;346(1):128-39. doi: 10.1016/j.ydbio.2010.07.003. Epub 2010 Jul 17.

15.

Small-molecule synergist of the Wnt/beta-catenin signaling pathway.

Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S.

Proc Natl Acad Sci U S A. 2007 May 1;104(18):7444-8. Epub 2007 Apr 25. Erratum in: Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12581. Jian, Xiaoying [added]; Randazzo, Paul A [added].

16.

Wnt signaling and human diseases: what are the therapeutic implications?

Luo J, Chen J, Deng ZL, Luo X, Song WX, Sharff KA, Tang N, Haydon RC, Luu HH, He TC.

Lab Invest. 2007 Feb;87(2):97-103. Epub 2007 Jan 8. Review.

17.

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways.

Takebe N, Harris PJ, Warren RQ, Ivy SP.

Nat Rev Clin Oncol. 2011 Feb;8(2):97-106. doi: 10.1038/nrclinonc.2010.196. Epub 2010 Dec 14. Review.

PMID:
21151206
18.

Wnt signaling and cancer development: therapeutic implication.

Paul S, Dey A.

Neoplasma. 2008;55(3):165-76. Review.

PMID:
18348648
19.

Regulation of bone mass by Wnt signaling.

Krishnan V, Bryant HU, Macdougald OA.

J Clin Invest. 2006 May;116(5):1202-9. Review.

20.

Physiological inhibitors of Wnt signaling.

Filipovich A, Gehrke I, Poll-Wolbeck SJ, Kreuzer KA.

Eur J Haematol. 2011 Jun;86(6):453-65. doi: 10.1111/j.1600-0609.2011.01592.x. Review.

PMID:
21342268
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