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Items: 1 to 20 of 318

1.

Polycomb complexes repress developmental regulators in murine embryonic stem cells.

Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, Levine SS, Wernig M, Tajonar A, Ray MK, Bell GW, Otte AP, Vidal M, Gifford DK, Young RA, Jaenisch R.

Nature. 2006 May 18;441(7091):349-53. Epub 2006 Apr 19.

PMID:
16625203
2.

Polycomb complexes act redundantly to repress genomic repeats and genes.

Leeb M, Pasini D, Novatchkova M, Jaritz M, Helin K, Wutz A.

Genes Dev. 2010 Feb 1;24(3):265-76. doi: 10.1101/gad.544410.

3.

Concise review: roles of polycomb group proteins in development and disease: a stem cell perspective.

Rajasekhar VK, Begemann M.

Stem Cells. 2007 Oct;25(10):2498-510. Epub 2007 Jun 28. Review.

4.

Control of developmental regulators by Polycomb in human embryonic stem cells.

Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, Chevalier B, Johnstone SE, Cole MF, Isono K, Koseki H, Fuchikami T, Abe K, Murray HL, Zucker JP, Yuan B, Bell GW, Herbolsheimer E, Hannett NM, Sun K, Odom DT, Otte AP, Volkert TL, Bartel DP, Melton DA, Gifford DK, Jaenisch R, Young RA.

Cell. 2006 Apr 21;125(2):301-13.

5.

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions.

Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K.

Genes Dev. 2006 May 1;20(9):1123-36. Epub 2006 Apr 17.

6.

The polycomb group protein Suz12 is required for embryonic stem cell differentiation.

Pasini D, Bracken AP, Hansen JB, Capillo M, Helin K.

Mol Cell Biol. 2007 May;27(10):3769-79. Epub 2007 Mar 5.

7.

Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity.

Endoh M, Endo TA, Endoh T, Fujimura Y, Ohara O, Toyoda T, Otte AP, Okano M, Brockdorff N, Vidal M, Koseki H.

Development. 2008 Apr;135(8):1513-24. doi: 10.1242/dev.014340. Epub 2008 Mar 13.

8.

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2.

Pasini D, Hansen KH, Christensen J, Agger K, Cloos PA, Helin K.

Genes Dev. 2008 May 15;22(10):1345-55. doi: 10.1101/gad.470008.

9.

CHD3 proteins and polycomb group proteins antagonistically determine cell identity in Arabidopsis.

Aichinger E, Villar CB, Farrona S, Reyes JC, Hennig L, Köhler C.

PLoS Genet. 2009 Aug;5(8):e1000605. doi: 10.1371/journal.pgen.1000605. Epub 2009 Aug 14.

10.

Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency.

Chamberlain SJ, Yee D, Magnuson T.

Stem Cells. 2008 Jun;26(6):1496-505. doi: 10.1634/stemcells.2008-0102. Epub 2008 Apr 10.

11.

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

Landeira D, Sauer S, Poot R, Dvorkina M, Mazzarella L, Jørgensen HF, Pereira CF, Leleu M, Piccolo FM, Spivakov M, Brookes E, Pombo A, Fisher C, Skarnes WC, Snoek T, Bezstarosti K, Demmers J, Klose RJ, Casanova M, Tavares L, Brockdorff N, Merkenschlager M, Fisher AG.

Nat Cell Biol. 2010 Jun;12(6):618-24. doi: 10.1038/ncb2065. Epub 2010 May 16.

12.

RYBP represses endogenous retroviruses and preimplantation- and germ line-specific genes in mouse embryonic stem cells.

Hisada K, Sánchez C, Endo TA, Endoh M, Román-Trufero M, Sharif J, Koseki H, Vidal M.

Mol Cell Biol. 2012 Mar;32(6):1139-49. doi: 10.1128/MCB.06441-11. Epub 2012 Jan 23.

13.

Stem cells primed for action: polycomb repressive complexes restrain the expression of lineage-specific regulators in embryonic stem cells.

Jørgensen HF, Giadrossi S, Casanova M, Endoh M, Koseki H, Brockdorff N, Fisher AG.

Cell Cycle. 2006 Jul;5(13):1411-4. Epub 2006 Jul 1.

PMID:
16855402
14.

Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes.

Pasini D, Malatesta M, Jung HR, Walfridsson J, Willer A, Olsson L, Skotte J, Wutz A, Porse B, Jensen ON, Helin K.

Nucleic Acids Res. 2010 Aug;38(15):4958-69. doi: 10.1093/nar/gkq244. Epub 2010 Apr 12.

15.

The role of the histone H2A ubiquitinase Sce in Polycomb repression.

Gutiérrez L, Oktaba K, Scheuermann JC, Gambetta MC, Ly-Hartig N, Müller J.

Development. 2012 Jan;139(1):117-27. doi: 10.1242/dev.074450. Epub 2011 Nov 17.

16.

MicroRNA-323-3p regulates the activity of polycomb repressive complex 2 (PRC2) via targeting the mRNA of embryonic ectoderm development (Eed) gene in mouse embryonic stem cells.

Zhang Y, Teng F, Luo GZ, Wang M, Tong M, Zhao X, Wang L, Wang XJ, Zhou Q.

J Biol Chem. 2013 Aug 16;288(33):23659-65. doi: 10.1074/jbc.M113.475608. Epub 2013 Jul 2.

17.

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells.

Pasini D, Cloos PA, Walfridsson J, Olsson L, Bukowski JP, Johansen JV, Bak M, Tommerup N, Rappsilber J, Helin K.

Nature. 2010 Mar 11;464(7286):306-10. doi: 10.1038/nature08788.

PMID:
20075857
18.

Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes.

He J, Shen L, Wan M, Taranova O, Wu H, Zhang Y.

Nat Cell Biol. 2013 Apr;15(4):373-84. doi: 10.1038/ncb2702. Epub 2013 Mar 17.

19.

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.

Ku M, Koche RP, Rheinbay E, Mendenhall EM, Endoh M, Mikkelsen TS, Presser A, Nusbaum C, Xie X, Chi AS, Adli M, Kasif S, Ptaszek LM, Cowan CA, Lander ES, Koseki H, Bernstein BE.

PLoS Genet. 2008 Oct;4(10):e1000242. doi: 10.1371/journal.pgen.1000242. Epub 2008 Oct 31.

20.

PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming.

Zhang Z, Jones A, Sun CW, Li C, Chang CW, Joo HY, Dai Q, Mysliwiec MR, Wu LC, Guo Y, Yang W, Liu K, Pawlik KM, Erdjument-Bromage H, Tempst P, Lee Y, Min J, Townes TM, Wang H.

Stem Cells. 2011 Feb;29(2):229-40. doi: 10.1002/stem.578.

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