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Items: 1 to 20 of 123

1.

S-(2-Succinyl)cysteine: a novel chemical modification of tissue proteins by a Krebs cycle intermediate.

Alderson NL, Wang Y, Blatnik M, Frizzell N, Walla MD, Lyons TJ, Alt N, Carson JA, Nagai R, Thorpe SR, Baynes JW.

Arch Biochem Biophys. 2006 Jun 1;450(1):1-8. Epub 2006 Mar 22.

PMID:
16624247
2.

Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.

Nagai R, Brock JW, Blatnik M, Baatz JE, Bethard J, Walla MD, Thorpe SR, Baynes JW, Frizzell N.

J Biol Chem. 2007 Nov 23;282(47):34219-28. Epub 2007 Aug 28.

3.

Chemical modification of muscle protein in diabetes.

Alt N, Carson JA, Alderson NL, Wang Y, Nagai R, Henle T, Thorpe SR, Baynes JW.

Arch Biochem Biophys. 2004 May 15;425(2):200-6.

PMID:
15111128
5.

Adipocyte protein modification by Krebs cycle intermediates and fumarate ester-derived succination.

Manuel AM, Frizzell N.

Amino Acids. 2013 Nov;45(5):1243-7. doi: 10.1007/s00726-013-1568-z. Epub 2013 Jul 28.

PMID:
23892396
6.

Succination of proteins in diabetes.

Frizzell N, Lima M, Baynes JW.

Free Radic Res. 2011 Jan;45(1):101-9. doi: 10.3109/10715762.2010.524643. Epub 2010 Oct 22. Review.

PMID:
20964553
7.

Succination of proteins by fumarate: mechanism of inactivation of glyceraldehyde-3-phosphate dehydrogenase in diabetes.

Blatnik M, Thorpe SR, Baynes JW.

Ann N Y Acad Sci. 2008 Apr;1126:272-5. doi: 10.1196/annals.1433.047.

8.

Tissue distribution of S-(2-succino)cysteine (2SC), a biomarker of mitochondrial stress in obesity and diabetes.

Thomas SA, Storey KB, Baynes JW, Frizzell N.

Obesity (Silver Spring). 2012 Feb;20(2):263-9. doi: 10.1038/oby.2011.340. Epub 2011 Dec 1.

9.

Tissue-specific variation in glycation of proteins in diabetes: evidence for a functional role of amadoriase enzymes.

Brown SM, Smith DM, Alt N, Thorpe SR, Baynes JW.

Ann N Y Acad Sci. 2005 Jun;1043:817-23. Review.

PMID:
16037309
10.

AGE-breakers cleave model compounds, but do not break Maillard crosslinks in skin and tail collagen from diabetic rats.

Yang S, Litchfield JE, Baynes JW.

Arch Biochem Biophys. 2003 Apr 1;412(1):42-6.

PMID:
12646266
11.

Succination of thiol groups in adipose tissue proteins in diabetes: succination inhibits polymerization and secretion of adiponectin.

Frizzell N, Rajesh M, Jepson MJ, Nagai R, Carson JA, Thorpe SR, Baynes JW.

J Biol Chem. 2009 Sep 18;284(38):25772-81. doi: 10.1074/jbc.M109.019257. Epub 2009 Jul 10.

12.

Tetracyclines inhibit protein glycation in experimental diabetes.

Ryan ME, Ramamurthy NS, Golub LM.

Adv Dent Res. 1998 Nov;12(2):152-8.

PMID:
9972141
13.

Novel inhibitors of glycation and AGE formation.

Rahbar S.

Cell Biochem Biophys. 2007;48(2-3):147-57.

PMID:
17709884
14.

Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes.

Yu Y, Thorpe SR, Jenkins AJ, Shaw JN, Sochaski MA, McGee D, Aston CE, Orchard TJ, Silvers N, Peng YG, McKnight JA, Baynes JW, Lyons TJ; DCCT/EDIC Research Group.

Diabetologia. 2006 Oct;49(10):2488-98. Epub 2006 Aug 29.

PMID:
16955213
15.

The succinated proteome.

Merkley ED, Metz TO, Smith RD, Baynes JW, Frizzell N.

Mass Spectrom Rev. 2014 Mar-Apr;33(2):98-109. doi: 10.1002/mas.21382. Epub 2013 Sep 30. Review.

16.

Protein aging by carboxymethylation of lysines generates sites for divalent metal and redox active copper binding: relevance to diseases of glycoxidative stress.

Saxena AK, Saxena P, Wu X, Obrenovich M, Weiss MF, Monnier VM.

Biochem Biophys Res Commun. 1999 Jul 5;260(2):332-8.

PMID:
10403771
17.

1H NMR-based metabonomic investigation of tributyl phosphate exposure in rats.

Neerathilingam M, Volk DE, Sarkar S, Alam TM, Alam MK, Ansari GA, Luxon BA.

Toxicol Lett. 2010 Nov 10;199(1):10-6. doi: 10.1016/j.toxlet.2010.07.013. Epub 2010 Aug 3.

PMID:
20688139
18.
19.

Effect of glucose concentration on formation of AGEs in erythrocytes in vitro.

Nagai R, Deemer EK, Brock JW, Thorpe SR, Baynes JW.

Ann N Y Acad Sci. 2005 Jun;1043:146-50.

PMID:
16037233
20.

Mitochondrial stress causes increased succination of proteins in adipocytes in response to glucotoxicity.

Frizzell N, Thomas SA, Carson JA, Baynes JW.

Biochem J. 2012 Jul 15;445(2):247-54. doi: 10.1042/BJ20112142.

PMID:
22524437
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