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Items: 1 to 20 of 880

1.

Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells.

Hu CJ, Iyer S, Sataur A, Covello KL, Chodosh LA, Simon MC.

Mol Cell Biol. 2006 May;26(9):3514-26.

2.

The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha.

Hu CJ, Sataur A, Wang L, Chen H, Simon MC.

Mol Biol Cell. 2007 Nov;18(11):4528-42. Epub 2007 Sep 5.

3.

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation.

Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC.

Mol Cell Biol. 2003 Dec;23(24):9361-74.

4.

The specific contribution of hypoxia-inducible factor-2alpha to hypoxic gene expression in vitro is limited and modulated by cell type-specific and exogenous factors.

Warnecke C, Weidemann A, Volke M, Schietke R, Wu X, Knaup KX, Hackenbeck T, Bernhardt W, Willam C, Eckardt KU, Wiesener MS.

Exp Cell Res. 2008 Jun 10;314(10):2016-27. doi: 10.1016/j.yexcr.2008.03.003. Epub 2008 Mar 18.

PMID:
18420194
6.

Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha.

Uchida T, Rossignol F, Matthay MA, Mounier R, Couette S, Clottes E, Clerici C.

J Biol Chem. 2004 Apr 9;279(15):14871-8. Epub 2004 Jan 26.

8.

Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment.

Bracken CP, Fedele AO, Linke S, Balrak W, Lisy K, Whitelaw ML, Peet DJ.

J Biol Chem. 2006 Aug 11;281(32):22575-85. Epub 2006 Jun 7.

9.

Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.

Raval RR, Lau KW, Tran MG, Sowter HM, Mandriota SJ, Li JL, Pugh CW, Maxwell PH, Harris AL, Ratcliffe PJ.

Mol Cell Biol. 2005 Jul;25(13):5675-86.

10.

The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia.

Maltepe E, Keith B, Arsham AM, Brorson JR, Simon MC.

Biochem Biophys Res Commun. 2000 Jun 24;273(1):231-8.

PMID:
10873592
11.

Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.

Puppo M, Battaglia F, Ottaviano C, Delfino S, Ribatti D, Varesio L, Bosco MC.

Mol Cancer Ther. 2008 Jul;7(7):1974-84. doi: 10.1158/1535-7163.MCT-07-2059.

12.

Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells.

Wang V, Davis DA, Haque M, Huang LE, Yarchoan R.

Cancer Res. 2005 Apr 15;65(8):3299-306.

13.

Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype.

Holmquist-Mengelbier L, Fredlund E, Löfstedt T, Noguera R, Navarro S, Nilsson H, Pietras A, Vallon-Christersson J, Borg A, Gradin K, Poellinger L, Påhlman S.

Cancer Cell. 2006 Nov;10(5):413-23.

14.

Subcellular localization and regulation of hypoxia-inducible factor-2alpha in vascular endothelial cells.

Takahashi R, Kobayashi C, Kondo Y, Nakatani Y, Kudo I, Kunimoto M, Imura N, Hara S.

Biochem Biophys Res Commun. 2004 Apr 23;317(1):84-91.

PMID:
15047151
15.

Hypoxia-inducible factor 1 transactivates the human leptin gene promoter.

Grosfeld A, Andre J, Hauguel-De Mouzon S, Berra E, Pouyssegur J, Guerre-Millo M.

J Biol Chem. 2002 Nov 8;277(45):42953-7. Epub 2002 Sep 4.

16.

Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha.

Shinojima T, Oya M, Takayanagi A, Mizuno R, Shimizu N, Murai M.

Carcinogenesis. 2007 Mar;28(3):529-36. Epub 2006 Aug 18.

17.

Two splice variants of the hypoxia-inducible factor HIF-1alpha as potential dimerization partners of ARNT2 in neurons.

Drutel G, Kathmann M, Héron A, Gros C, Macé S, Schwartz JC, Arrang JM.

Eur J Neurosci. 2000 Oct;12(10):3701-8.

PMID:
11029639
18.

Hypoxia-inducible factor-1alpha and -2alpha additively promote endothelial vasculogenic properties.

Ben-Shoshan J, Maysel-Auslender S, Luboshits G, Barshack I, Polak-Charcon S, Tzahor E, Keren G, George J.

J Vasc Res. 2009;46(4):299-310. doi: 10.1159/000181546. Epub 2008 Dec 11.

PMID:
19077391
19.

Hypoxia-inducible factor-1 (HIF-1) is a transcriptional activator of the TrkB neurotrophin receptor gene.

Martens LK, Kirschner KM, Warnecke C, Scholz H.

J Biol Chem. 2007 May 11;282(19):14379-88. Epub 2007 Mar 20.

20.

Regulation of gene expression by the hypoxia-inducible factors.

Fedele AO, Whitelaw ML, Peet DJ.

Mol Interv. 2002 Jul;2(4):229-43. Review.

PMID:
14993394
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