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Items: 1 to 20 of 95

1.

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.

Rowe DC, McGettrick AF, Latz E, Monks BG, Gay NJ, Yamamoto M, Akira S, O'Neill LA, Fitzgerald KA, Golenbock DT.

Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6299-304. Epub 2006 Apr 7.

2.

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.

Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT.

J Exp Med. 2003 Oct 6;198(7):1043-55. Epub 2003 Sep 29. Erratum in: J Exp Med. 2003 Nov 3;198(9):following 1450.

3.

Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling.

Tanimura N, Saitoh S, Matsumoto F, Akashi-Takamura S, Miyake K.

Biochem Biophys Res Commun. 2008 Mar 28;368(1):94-9. doi: 10.1016/j.bbrc.2008.01.061. Epub 2008 Jan 28.

PMID:
18222170
5.

Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis.

Lundberg AM, Ketelhuth DF, Johansson ME, Gerdes N, Liu S, Yamamoto M, Akira S, Hansson GK.

Cardiovasc Res. 2013 Jul 15;99(2):364-73. doi: 10.1093/cvr/cvt033. Epub 2013 Feb 14.

6.

Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain.

Piao W, Ru LW, Piepenbrink KH, Sundberg EJ, Vogel SN, Toshchakov VY.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19036-41. doi: 10.1073/pnas.1313575110. Epub 2013 Nov 5.

7.

Absence of TRAM restricts Toll-like receptor 4 signaling in vascular endothelial cells to the MyD88 pathway.

Harari OA, Alcaide P, Ahl D, Luscinskas FW, Liao JK.

Circ Res. 2006 May 12;98(9):1134-40. Epub 2006 Mar 30.

8.

Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM.

Wang L, Trebicka E, Fu Y, Waggoner L, Akira S, Fitzgerald KA, Kagan JC, Cherayil BJ.

J Innate Immun. 2011;3(5):437-46. doi: 10.1159/000324833. Epub 2011 Apr 14.

9.

Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.

McGettrick AF, Brint EK, Palsson-McDermott EM, Rowe DC, Golenbock DT, Gay NJ, Fitzgerald KA, O'Neill LA.

Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9196-201. Epub 2006 Jun 6.

10.

Inhibition of TLR4 signaling by TRAM-derived decoy peptides in vitro and in vivo.

Piao W, Vogel SN, Toshchakov VY.

J Immunol. 2013 Mar 1;190(5):2263-72. doi: 10.4049/jimmunol.1202703. Epub 2013 Jan 23.

11.

Melatonin modulates TLR4-mediated inflammatory genes through MyD88- and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells.

Xia MZ, Liang YL, Wang H, Chen X, Huang YY, Zhang ZH, Chen YH, Zhang C, Zhao M, Xu DX, Song LH.

J Pineal Res. 2012 Nov;53(4):325-34. doi: 10.1111/j.1600-079X.2012.01002.x. Epub 2012 Apr 27.

PMID:
22537289
13.

The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4.

Verstak B, Stack J, Ve T, Mangan M, Hjerrild K, Jeon J, Stahl R, Latz E, Gay N, Kobe B, Bowie AG, Mansell A.

J Leukoc Biol. 2014 Sep;96(3):427-36. doi: 10.1189/jlb.2A0913-487R. Epub 2014 May 8.

14.

Dominant role of the MyD88-dependent signaling pathway in mediating early endotoxin-induced murine ileus.

Buchholz BM, Billiar TR, Bauer AJ.

Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G531-8. doi: 10.1152/ajpgi.00060.2010. Epub 2010 May 27.

15.

Absence of TRIF signaling in lipopolysaccharide-stimulated murine mast cells.

Keck S, Müller I, Fejer G, Savic I, Tchaptchet S, Nielsen PJ, Galanos C, Huber M, Freudenberg MA.

J Immunol. 2011 May 1;186(9):5478-88. doi: 10.4049/jimmunol.1000458. Epub 2011 Mar 25.

16.

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling.

Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, Takeda K, Akira S.

J Immunol. 2002 Dec 15;169(12):6668-72.

17.
19.

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O, Sugiyama M, Okabe M, Takeda K, Akira S.

Science. 2003 Aug 1;301(5633):640-3. Epub 2003 Jul 10.

20.

MyD88 but not TRIF is essential for osteoclastogenesis induced by lipopolysaccharide, diacyl lipopeptide, and IL-1alpha.

Sato N, Takahashi N, Suda K, Nakamura M, Yamaki M, Ninomiya T, Kobayashi Y, Takada H, Shibata K, Yamamoto M, Takeda K, Akira S, Noguchi T, Udagawa N.

J Exp Med. 2004 Sep 6;200(5):601-11.

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