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Results: 1 to 20 of 180

1.

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.

Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T.

Nat Med. 2006 Apr;12(4):446-51. Epub 2006 Mar 26. Erratum in: Nat Med. 2010 Jan;16(1):129.

PMID:
16565722
[PubMed - indexed for MEDLINE]
2.

Function of oxidative stress in the regulation of hematopoietic stem cell-niche interaction.

Hosokawa K, Arai F, Yoshihara H, Nakamura Y, Gomei Y, Iwasaki H, Miyamoto K, Shima H, Ito K, Suda T.

Biochem Biophys Res Commun. 2007 Nov 23;363(3):578-83. Epub 2007 Sep 18.

PMID:
17897629
[PubMed - indexed for MEDLINE]
3.

NAD(P)H oxidase plays a crucial role in PDGF-induced proliferation of hepatic stellate cells.

Adachi T, Togashi H, Suzuki A, Kasai S, Ito J, Sugahara K, Kawata S.

Hepatology. 2005 Jun;41(6):1272-81.

PMID:
15915457
[PubMed - indexed for MEDLINE]
4.

Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAPK.

Kim H, Rhee SH, Kokkotou E, Na X, Savidge T, Moyer MP, Pothoulakis C, LaMont JT.

J Biol Chem. 2005 Jun 3;280(22):21237-45. Epub 2005 Mar 14.

PMID:
15767259
[PubMed - indexed for MEDLINE]
Free Article
5.

Inhibition of p38 mitogen-activated protein kinase promotes ex vivo hematopoietic stem cell expansion.

Wang Y, Kellner J, Liu L, Zhou D.

Stem Cells Dev. 2011 Jul;20(7):1143-52. doi: 10.1089/scd.2010.0413. Epub 2011 Feb 24.

PMID:
21198398
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

p38MAPK-Dependent sensitivity of Ewing's sarcoma family of tumors to fenretinide-induced cell death.

Myatt SS, Redfern CP, Burchill SA.

Clin Cancer Res. 2005 Apr 15;11(8):3136-48.

PMID:
15837770
[PubMed - indexed for MEDLINE]
Free Article
7.

Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells.

Taniguchi Ishikawa E, Gonzalez-Nieto D, Ghiaur G, Dunn SK, Ficker AM, Murali B, Madhu M, Gutstein DE, Fishman GI, Barrio LC, Cancelas JA.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9071-6. doi: 10.1073/pnas.1120358109. Epub 2012 May 18.

PMID:
22611193
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche.

Jang YY, Sharkis SJ.

Blood. 2007 Oct 15;110(8):3056-63. Epub 2007 Jun 26.

PMID:
17595331
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice.

Ramesh G, Reeves WB.

Am J Physiol Renal Physiol. 2005 Jul;289(1):F166-74. Epub 2005 Feb 8.

PMID:
15701814
[PubMed - indexed for MEDLINE]
Free Article
10.

Evidence that age-related changes in p38 MAP kinase contribute to the decreased steroid production by the adrenocortical cells from old rats.

Abidi P, Leers-Sucheta S, Cortez Y, Han J, Azhar S.

Aging Cell. 2008 Mar;7(2):168-78. doi: 10.1111/j.1474-9726.2007.00364.x. Epub 2008 Jan 28.

PMID:
18241324
[PubMed - indexed for MEDLINE]
Free Article
11.

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.

Juntilla MM, Patil VD, Calamito M, Joshi RP, Birnbaum MJ, Koretzky GA.

Blood. 2010 May 20;115(20):4030-8. doi: 10.1182/blood-2009-09-241000. Epub 2010 Mar 30.

PMID:
20354168
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Oxygen-glucose deprivation activates 5-lipoxygenase mediated by oxidative stress through the p38 mitogen-activated protein kinase pathway in PC12 cells.

Li CT, Zhang WP, Lu YB, Fang SH, Yuan YM, Qi LL, Zhang LH, Huang XJ, Zhang L, Chen Z, Wei EQ.

J Neurosci Res. 2009 Mar;87(4):991-1001. doi: 10.1002/jnr.21913.

PMID:
18951527
[PubMed - indexed for MEDLINE]
13.

Inhibition of p38 MAPK activity promotes ex vivo expansion of human cord blood hematopoietic stem cells.

Zou J, Zou P, Wang J, Li L, Wang Y, Zhou D, Liu L.

Ann Hematol. 2012 Jun;91(6):813-23. doi: 10.1007/s00277-011-1397-7. Epub 2012 Jan 19.

PMID:
22258328
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Regulation of reactive oxygen species and genomic stability in hematopoietic stem cells.

Naka K, Muraguchi T, Hoshii T, Hirao A.

Antioxid Redox Signal. 2008 Nov;10(11):1883-94. doi: 10.1089/ars.2008.2114. Review.

PMID:
18627347
[PubMed - indexed for MEDLINE]
15.

Acute adrenergic stress inhibits proliferation of murine hematopoietic progenitor cells via p38/MAPK signaling.

Schraml E, Fuchs R, Kotzbeck P, Grillari J, Schauenstein K.

Stem Cells Dev. 2009 Mar;18(2):215-27. doi: 10.1089/scd.2008.0072.

PMID:
18444787
[PubMed - indexed for MEDLINE]
16.

The role of p38 MAPK activation in auranofin-induced apoptosis of human promyelocytic leukaemia HL-60 cells.

Park SJ, Kim IS.

Br J Pharmacol. 2005 Oct;146(4):506-13.

PMID:
16086031
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor.

Schmeck B, Zahlten J, Moog K, van Laak V, Huber S, Hocke AC, Opitz B, Hoffmann E, Kracht M, Zerrahn J, Hammerschmidt S, Rosseau S, Suttorp N, Hippenstiel S.

J Biol Chem. 2004 Dec 17;279(51):53241-7. Epub 2004 Oct 13.

PMID:
15485852
[PubMed - indexed for MEDLINE]
Free Article
18.

Ethanol-induced oxidative stress is mediated by p38 MAPK pathway in mouse hippocampal cells.

Ku BM, Lee YK, Jeong JY, Mun J, Han JY, Roh GS, Kim HJ, Cho GJ, Choi WS, Yi GS, Kang SS.

Neurosci Lett. 2007 May 23;419(1):64-7. Epub 2007 Mar 28.

PMID:
17420100
[PubMed - indexed for MEDLINE]
19.

Thyroid-stimulating hormone and cyclic AMP activate p38 mitogen-activated protein kinase cascade. Involvement of protein kinase A, rac1, and reactive oxygen species.

Pomerance M, Abdullah HB, Kamerji S, Correze C, Blondeau JP.

J Biol Chem. 2000 Dec 22;275(51):40539-46.

PMID:
11006268
[PubMed - indexed for MEDLINE]
Free Article
20.

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.

Miyamoto K, Araki KY, Naka K, Arai F, Takubo K, Yamazaki S, Matsuoka S, Miyamoto T, Ito K, Ohmura M, Chen C, Hosokawa K, Nakauchi H, Nakayama K, Nakayama KI, Harada M, Motoyama N, Suda T, Hirao A.

Cell Stem Cell. 2007 Jun 7;1(1):101-12. doi: 10.1016/j.stem.2007.02.001.

PMID:
18371339
[PubMed - indexed for MEDLINE]
Free Article
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