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Items: 1 to 20 of 128

1.

Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma.

Shah US, Dhir R, Gollin SM, Chandran UR, Lewis D, Acquafondata M, Pflug BR.

Hum Pathol. 2006 Apr;37(4):401-9. Epub 2006 Feb 7.

PMID:
16564913
2.

Inhibition of fatty acid synthase activity in prostate cancer cells by dutasteride.

Schmidt LJ, Ballman KV, Tindall DJ.

Prostate. 2007 Jul 1;67(10):1111-20.

PMID:
17477363
3.

Caveolin-1 is required for the upregulation of fatty acid synthase (FASN), a tumor promoter, during prostate cancer progression.

Di Vizio D, Sotgia F, Williams TM, Hassan GS, Capozza F, Frank PG, Pestell RG, Loda M, Freeman MR, Lisanti MP.

Cancer Biol Ther. 2007 Aug;6(8):1263-8. Epub 2007 May 17.

PMID:
17786030
4.

High prevalence of fatty acid synthase expression in colorectal cancers in Middle Eastern patients and its potential role as a therapeutic target.

Uddin S, Hussain AR, Ahmed M, Abubaker J, Al-Sanea N, Abduljabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Bavi P, Al-Kuraya KS.

Am J Gastroenterol. 2009 Jul;104(7):1790-801. doi: 10.1038/ajg.2009.230. Epub 2009 Jun 2.

PMID:
19491830
5.

KLF5 enhances SREBP-1 action in androgen-dependent induction of fatty acid synthase in prostate cancer cells.

Lee MY, Moon JS, Park SW, Koh YK, Ahn YH, Kim KS.

Biochem J. 2009 Jan 1;417(1):313-22. doi: 10.1042/BJ20080762.

PMID:
18774944
6.

Analyzing effects of extra-virgin olive oil polyphenols on breast cancer-associated fatty acid synthase protein expression using reverse-phase protein microarrays.

Menendez JA, Vazquez-Martin A, Oliveras-Ferraros C, Garcia-Villalba R, Carrasco-Pancorbo A, Fernandez-Gutierrez A, Segura-Carretero A.

Int J Mol Med. 2008 Oct;22(4):433-9.

PMID:
18813848
7.

Up-regulation of acetyl-CoA carboxylase alpha and fatty acid synthase by human epidermal growth factor receptor 2 at the translational level in breast cancer cells.

Yoon S, Lee MY, Park SW, Moon JS, Koh YK, Ahn YH, Park BW, Kim KS.

J Biol Chem. 2007 Sep 7;282(36):26122-31. Epub 2007 Jul 13.

8.

Clinical significance of epidermal growth factor receptor protein overexpression and gene copy number gains in prostate cancer.

Schlomm T, Kirstein P, Iwers L, Daniel B, Steuber T, Walz J, Chun FH, Haese A, Kollermann J, Graefen M, Huland H, Sauter G, Simon R, Erbersdobler A.

Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6579-84.

9.

Fatty acid synthase expression defines distinct molecular signatures in prostate cancer.

Rossi S, Graner E, Febbo P, Weinstein L, Bhattacharya N, Onody T, Bubley G, Balk S, Loda M.

Mol Cancer Res. 2003 Aug;1(10):707-15.

10.

The gene for polycomb group protein enhancer of zeste homolog 2 (EZH2) is amplified in late-stage prostate cancer.

Saramäki OR, Tammela TL, Martikainen PM, Vessella RL, Visakorpi T.

Genes Chromosomes Cancer. 2006 Jul;45(7):639-45.

PMID:
16575874
11.

Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells.

Vazquez-Martin A, Colomer R, Brunet J, Lupu R, Menendez JA.

Cell Prolif. 2008 Feb;41(1):59-85. doi: 10.1111/j.1365-2184.2007.00498.x.

PMID:
18211286
13.

Fluorescent in situ hybridization study of c-myc oncogene copy number in prostate cancer.

Mark HF, Samy M, Santoro K, Mark S, Feldman D.

Exp Mol Pathol. 2000 Feb;68(1):65-9.

PMID:
10640455
14.

Characterization of a novel anti-fatty acid synthase (FASN) antiserum in breast tissue.

Jensen KC, Schaeffer DF, Cheang M, Montgomery K, West RB, Gilks CB, Ross D, Turashvili G, Schnitt S, van de Rijn M.

Mod Pathol. 2008 Dec;21(12):1413-20. doi: 10.1038/modpathol.2008.163. Epub 2008 Sep 26.

15.

A new mechanism of drug resistance in breast cancer cells: fatty acid synthase overexpression-mediated palmitate overproduction.

Liu H, Liu Y, Zhang JT.

Mol Cancer Ther. 2008 Feb;7(2):263-70. doi: 10.1158/1535-7163.MCT-07-0445.

16.

Evaluation of HER-2/neu expression in prostatic adenocarcinoma: a requested for a standardized, organ specific methodology.

Sanchez KM, Sweeney CJ, Mass R, Koch MO, Eckert GJ, Geary WA, Baldridge LA, Zhang S, Eble JN, Cheng L.

Cancer. 2002 Oct 15;95(8):1650-5.

17.

Identification of putative oncogenes in lung adenocarcinoma by a comprehensive functional genomic approach.

Li R, Wang H, Bekele BN, Yin Z, Caraway NP, Katz RL, Stass SA, Jiang F.

Oncogene. 2006 Apr 27;25(18):2628-35.

PMID:
16369491
18.

Bone morphogenic factor gene dosage abnormalities in prostatic intraepithelial neoplasia and prostate cancer.

Doak SH, Jenkins SA, Hurle RA, Varma M, Hawizy A, Kynaston HG, Parry JM.

Cancer Genet Cytogenet. 2007 Jul 15;176(2):161-5.

PMID:
17656261
19.
20.

Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer.

Migita T, Ruiz S, Fornari A, Fiorentino M, Priolo C, Zadra G, Inazuka F, Grisanzio C, Palescandolo E, Shin E, Fiore C, Xie W, Kung AL, Febbo PG, Subramanian A, Mucci L, Ma J, Signoretti S, Stampfer M, Hahn WC, Finn S, Loda M.

J Natl Cancer Inst. 2009 Apr 1;101(7):519-32. doi: 10.1093/jnci/djp030. Epub 2009 Mar 24.

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