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16556852,15210959,18039927,16141411,17053170,19729607,22367754,25496323,16730733,17846428,17960026,25512280,18029360,25589556,17005185,23788762,16670775,19168441,12777468,14512442,19637290,20075335,22790567,22095132,17916878,14726413,22353356,16902247,15976321,21148432,23747827,22772754,20844270,16917103,18852364,16825483,16054048,16254209,25749868,24140409,18787185,10639163,23051557,14604434,19166963,18802017,17587765,22209005,16352604,15994327,12091489,18924609,25462452,26603933,23812592,18060750,22922992,17657311,19342446,26253613,16798073,18761326,15514210,23523156,24576892,19481530,21862012,24212237,23388354,23600914,27383786,27365310,26695502,18509196,21817095,19217108,18271871,20339114,18703020,15817453,20037141,20733269,16054053,17405904,18490524,22753765,16024918,23519695,20570635,21138980,19895785,16857950,18369155,19405812,22481067,20466885,16778964,18252848,27601313,16325781,18820007,18635820,22984960,21039336,15319426,23340182,23846804,17991739,11790770,19339012,19376519,16524875,20431058,27230131,20448206,17020879,21957962,22190590,20170635,17186944,28739279,21527752,28315462,18793613,11909955,28165022,17848583,20675829,18006857,19803427,19325142,25724068,24595513,16888235,20064973,26255968,23693076,18599800,19713213,16357317,20018934,20083572,12370265,11504730,21910087,28082258,30825148,23011313,17526932,18945429,26288135,26081100,29599133,15922656,19422933,10924356,18314463,15633131,17466310,27196068,25302608,11350058,18619413,17166844,27251372,22429094,25509420,19797709,17499231,22806829,24947527,21295304,19372466,35737216,20374257,24385509,25249572,21289254,20488992,25305669,18827283,22338009,26296893,17148552,20566875,21134376,24833118,11500512,32243091,18762171,17363694,17293612,33058851,29374468,22677519,16680026,12615696,30060101,12586329,25436422,18723776,22668787,17032648,12359125,22179025,24360166,21972082,17761632,22673513,17967783,22707265,22940078,28583767,12615685,19398602,11579092,17556891,17070501,20656214,23246324,26489644,17390217,19362310,23150660,16187691,17194745,16723355,32705595,8937522,16567856,14643795,18160655,16702602,11927274,20056921,18292583,21824529,22365996,16870176,12822736,17459600,22904275,19633360,33125792,19965597,23562078,21343303,26941018,14668945,20110576,1932099,21036914,16971496,11731329,24838154,11035776,19175378,23015358,11907146,19574561,18084736,15240127,24587984,20203311,2318824,26287243,2829803,19395734,19286612,14734645,21821149,20530872,24367046,28882873,24972087,16887795,32354992,30545366,18460328,16092061,15459087,23661709,12679197,11341963,19949102,19429425,22237709,20972840,20576876,10787172,34461069,18769226,35897824,22749359,2918251,19270375,23158108,3559403,20382126,24582563,22488423,29361501,33141061,1645339,24115033,18322240,10893411,27784702,11950703,17204665,16709952,22198513,24320932,26220175,17430243,25732853,20395559,32196455,32558932,21302003,15772424,26345803,21864714,30633988,30235209,22862945,23719382,22580900,16182194,11820795,21978921,16858612,11186392,17825296,17050734,34122329,25332231,31377319,16935283,10092505,22845468,15287499,11606068,20798376,25398214,17222851,25339664,33050595,17430244,15857310,1911862,31003090,22884520,15522819,36017862,18221121,29172034,15485881,16024916,23100511,36271611,3341992,31111899,20190811,22414908,31884588,33390931,23983199,17408620,21122624,15891397,31719160,25503882,33188828,36430223,11696569,24901717,2988931,34025647,2297343,30127022,21876547,8558077,19057652,7890720,22508840,21810484,7929116,27508871,26416507,18366990,16990560,1909865,10878804,19239689,23897420,8364017,8555257,8663188,18614014,35234362,14499733,23206728,2844757,28205181,12573359,31136841,21438812,18508037,18547429,8180249,22872754,15905101,15361799,2171942,14729661,18997165,22155456,11441141,23172659,21830321,36996698,227899,9090297,19556716,20975842,25473102,23770099,12700341,23500544,16408775,21389634,25405320,23290500,11182136,14602065,24914897,3637204,33221536,29704538,26332942,19651406,30548066,30576926,19122238,10954705,23743223,23455994,11372425,28264879,28167703,11669638,11876263,35725197,2839973,22431312,30930171,9507990,12021839,25485894,23584088,9643354,29337706,33833449,18238900,25084760,9335947,25875769,11584078,23072980,7615524,31327756,11565568,27050513,9316429,30174957,25713191,4942408,24386159,21157966,28794002,36881721,12951366,32719109,26015858,36592658,5126640,20926130,8895069,11316799,12657643,31251843,21488784,35500666,33478937,19378935,35168806,19935203,31933239,35575928,35432274,19729679,2193824,29853567,21488783,11099405,1431592,19704950,23033213,35237989,21741992,29161079,30364132,9186624,11486367,31181660,31917335,32424095,15891399,29522754,20574076,7648003,10632036,20843692,33723592,35143844,3190824,20627678,29658264,22418574,28205162,36010867,31167119,11733542,30948800,35599093[uid]

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LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL.

Wang N, Ranalletta M, Matsuura F, Peng F, Tall AR. Wang N, et al. Arterioscler Thromb Vasc Biol. 2006 Jun;26(6):1310-6. doi: 10.1161/01.ATV.0000218998.75963.02. Epub 2006 Mar 23. Arterioscler Thromb Vasc Biol. 2006. PMID: 16556852

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.

Wang N, Lan D, Chen W, Matsuura F, Tall AR. Wang N, et al. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9774-9. doi: 10.1073/pnas.0403506101. Epub 2004 Jun 21. Proc Natl Acad Sci U S A. 2004. PMID: 15210959 Free PMC article.

ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain.

Wang N, Yvan-Charvet L, Lütjohann D, Mulder M, Vanmierlo T, Kim TW, Tall AR. Wang N, et al. FASEB J. 2008 Apr;22(4):1073-82. doi: 10.1096/fj.07-9944com. Epub 2007 Nov 26. FASEB J. 2008. PMID: 18039927

Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages.

Rigamonti E, Helin L, Lestavel S, Mutka AL, Lepore M, Fontaine C, Bouhlel MA, Bultel S, Fruchart JC, Ikonen E, Clavey V, Staels B, Chinetti-Gbaguidi G. Rigamonti E, et al. Circ Res. 2005 Sep 30;97(7):682-9. doi: 10.1161/01.RES.0000184678.43488.9f. Epub 2005 Sep 1. Circ Res. 2005. PMID: 16141411

Cell surface localization of ABCG1 does not require LXR activation.

Xie Q, Engel T, Schnoor M, Niehaus J, Hofnagel O, Buers I, Cullen P, Seedorf U, Assmann G, Lorkowski S. Xie Q, et al. Arterioscler Thromb Vasc Biol. 2006 Nov;26(11):e143-4; author reply e145. doi: 10.1161/01.ATV.0000245790.47112.b2. Arterioscler Thromb Vasc Biol. 2006. PMID: 17053170 No abstract available.

Stimulation of cholesterol efflux by LXR agonists in cholesterol-loaded human macrophages is ABCA1-dependent but ABCG1-independent.

Larrede S, Quinn CM, Jessup W, Frisdal E, Olivier M, Hsieh V, Kim MJ, Van Eck M, Couvert P, Carrie A, Giral P, Chapman MJ, Guerin M, Le Goff W. Larrede S, et al. Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1930-6. doi: 10.1161/ATVBAHA.109.194548. Epub 2009 Sep 3. Arterioscler Thromb Vasc Biol. 2009. PMID: 19729607

Phospholipase A(2)-modified low-density lipoprotein activates liver X receptor in human macrophages.

Morbitzer D, Namgaladze D, Brüne B. Morbitzer D, et al. Cell Biochem Biophys. 2012 Jun;63(2):143-9. doi: 10.1007/s12013-012-9351-4. Cell Biochem Biophys. 2012. PMID: 22367754

Alpinetin enhances cholesterol efflux and inhibits lipid accumulation in oxidized low-density lipoprotein-loaded human macrophages.

Jiang Z, Sang H, Fu X, Liang Y, Li L. Jiang Z, et al. Biotechnol Appl Biochem. 2015 Nov-Dec;62(6):840-7. doi: 10.1002/bab.1328. Epub 2015 May 17. Biotechnol Appl Biochem. 2015. PMID: 25496323

Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element.

Uehara Y, Miura S, von Eckardstein A, Abe S, Fujii A, Matsuo Y, Rust S, Lorkowski S, Assmann G, Yamada T, Saku K. Uehara Y, et al. Atherosclerosis. 2007 Mar;191(1):11-21. doi: 10.1016/j.atherosclerosis.2006.04.018. Epub 2006 May 30. Atherosclerosis. 2007. PMID: 16730733

High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1.

Terasaka N, Wang N, Yvan-Charvet L, Tall AR. Terasaka N, et al. Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15093-8. doi: 10.1073/pnas.0704602104. Epub 2007 Sep 10. Proc Natl Acad Sci U S A. 2007. PMID: 17846428 Free PMC article.

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