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Results: 1 to 20 of 318

1.

Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis.

Noël G, Godon C, Fernet M, Giocanti N, Mégnin-Chanet F, Favaudon V.

Mol Cancer Ther. 2006 Mar;5(3):564-74.

PMID:
16546970
[PubMed - indexed for MEDLINE]
Free Article
2.

4-Amino-1,8-naphthalimide: a novel inhibitor of poly(ADP-ribose) polymerase and radiation sensitizer.

Schlicker A, Peschke P, Bürkle A, Hahn EW, Kim JH.

Int J Radiat Biol. 1999 Jan;75(1):91-100.

PMID:
9972795
[PubMed - indexed for MEDLINE]
3.

PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility.

Godon C, Cordelières FP, Biard D, Giocanti N, Mégnin-Chanet F, Hall J, Favaudon V.

Nucleic Acids Res. 2008 Aug;36(13):4454-64. doi: 10.1093/nar/gkn403. Epub 2008 Jul 4.

PMID:
18603595
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Poly(ADP-ribose) polymerase activity prevents signaling pathways for cell cycle arrest after DNA methylating agent exposure.

Horton JK, Stefanick DF, Naron JM, Kedar PS, Wilson SH.

J Biol Chem. 2005 Apr 22;280(16):15773-85. Epub 2005 Feb 7.

PMID:
15701627
[PubMed - indexed for MEDLINE]
Free Article
5.

PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation.

Chalmers A, Johnston P, Woodcock M, Joiner M, Marples B.

Int J Radiat Oncol Biol Phys. 2004 Feb 1;58(2):410-9.

PMID:
14751510
[PubMed - indexed for MEDLINE]
6.

Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair.

Bryant HE, Helleday T.

Nucleic Acids Res. 2006 Mar 23;34(6):1685-91. Print 2006.

PMID:
16556909
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair.

Löser DA, Shibata A, Shibata AK, Woodbine LJ, Jeggo PA, Chalmers AJ.

Mol Cancer Ther. 2010 Jun;9(6):1775-87. doi: 10.1158/1535-7163.MCT-09-1027. Epub 2010 Jun 8.

PMID:
20530711
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Alkylation DNA damage in combination with PARP inhibition results in formation of S-phase-dependent double-strand breaks.

Heacock ML, Stefanick DF, Horton JK, Wilson SH.

DNA Repair (Amst). 2010 Aug 5;9(8):929-36. doi: 10.1016/j.dnarep.2010.05.007. Epub 2010 Jun 22.

PMID:
20573551
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The novel poly(ADP-Ribose) polymerase inhibitor, AG14361, sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks.

Smith LM, Willmore E, Austin CA, Curtin NJ.

Clin Cancer Res. 2005 Dec 1;11(23):8449-57.

PMID:
16322308
[PubMed - indexed for MEDLINE]
Free Article
10.

Induction of apoptosis by the inhibitors of poly(ADP-ribose)polymerase in HeLa cells.

Ghosh U, Bhattacharyya NP.

Mol Cell Biochem. 2009 Jan;320(1-2):15-23. doi: 10.1007/s11010-008-9894-2. Epub 2008 Aug 10.

PMID:
18695944
[PubMed - indexed for MEDLINE]
11.

Poly(ADP-ribose) polymerase inhibition reduces tumor necrosis factor-induced inflammatory response in rheumatoid synovial fibroblasts.

García S, Bodaño A, Pablos JL, Gómez-Reino JJ, Conde C.

Ann Rheum Dis. 2008 May;67(5):631-7. Epub 2007 Sep 21.

PMID:
17890271
[PubMed - indexed for MEDLINE]
12.

Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.

Veuger SJ, Curtin NJ, Richardson CJ, Smith GC, Durkacz BW.

Cancer Res. 2003 Sep 15;63(18):6008-15.

PMID:
14522929
[PubMed - indexed for MEDLINE]
Free Article
13.

ATR signaling mediates an S-phase checkpoint after inhibition of poly(ADP-ribose) polymerase activity.

Horton JK, Stefanick DF, Kedar PS, Wilson SH.

DNA Repair (Amst). 2007 Jun 1;6(6):742-50. Epub 2007 Feb 9.

PMID:
17292679
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Radiosensitization effect of poly(ADP-ribose) polymerase inhibition in cells exposed to low and high liner energy transfer radiation.

Hirai T, Shirai H, Fujimori H, Okayasu R, Sasai K, Masutani M.

Cancer Sci. 2012 Jun;103(6):1045-50. doi: 10.1111/j.1349-7006.2012.02268.x. Epub 2012 Apr 19.

PMID:
22404155
[PubMed - indexed for MEDLINE]
15.
16.

A stronger DNA damage-induced G2 checkpoint due to over-activated CHK1 in the absence of PARP-1.

Lu HR, Wang X, Wang Y.

Cell Cycle. 2006 Oct;5(20):2364-70. Epub 2006 Oct 16.

PMID:
17102615
[PubMed - indexed for MEDLINE]
Free Article
17.

Increased susceptibility of poly(ADP-ribose) polymerase-1 knockout cells to antitumor triazoloacridone C-1305 is associated with permanent G2 cell cycle arrest.

Wesierska-Gadek J, Schloffer D, Gueorguieva M, Uhl M, Skladanowski A.

Cancer Res. 2004 Jul 1;64(13):4487-97.

PMID:
15231658
[PubMed - indexed for MEDLINE]
Free Article
18.

Radiosensitization of human and rodent cell lines by INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase.

Brock WA, Milas L, Bergh S, Lo R, Szabó C, Mason KA.

Cancer Lett. 2004 Mar 18;205(2):155-60.

PMID:
15036647
[PubMed - indexed for MEDLINE]
19.

The expression of poly(ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication complex.

Simbulan-Rosenthal CM, Rosenthal DS, Hilz H, Hickey R, Malkas L, Applegren N, Wu Y, Bers G, Smulson ME.

Biochemistry. 1996 Sep 10;35(36):11622-33.

PMID:
8794742
[PubMed - indexed for MEDLINE]
20.

Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery.

Noël G, Giocanti N, Fernet M, Mégnin-Chanet F, Favaudon V.

BMC Cell Biol. 2003 Jul 16;4:7.

PMID:
12866953
[PubMed - indexed for MEDLINE]
Free PMC Article

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