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Results: 1 to 20 of 471

1.

The opioid peptide nociceptin/orphanin FQ mediates prostaglandin E2-induced allodynia, tactile pain associated with nerve injury.

Okuda-Ashitaka E, Minami T, Matsumura S, Takeshima H, Reinscheid RK, Civelli O, Ito S.

Eur J Neurosci. 2006 Feb;23(4):995-1004.

PMID:
16519664
[PubMed - indexed for MEDLINE]
2.

Characterization of nociceptin/orphanin FQ-induced pain responses by the novel receptor antagonist N-(4-amino-2-methylquinolin-6-yl)-2-(4-ethylphenoxymethyl) benzamide monohydrochloride.

Muratani T, Minami T, Enomoto U, Sakai M, Okuda-Ashitaka E, Kiyokane K, Mori H, Ito S.

J Pharmacol Exp Ther. 2002 Oct;303(1):424-30.

PMID:
12235279
[PubMed - indexed for MEDLINE]
Free Article
3.

Attenuation of neuropathic pain by the nociceptin/orphanin FQ antagonist JTC-801 is mediated by inhibition of nitric oxide production.

Mabuchi T, Matsumura S, Okuda-Ashitaka E, Kitano T, Kojima H, Nagano T, Minami T, Ito S.

Eur J Neurosci. 2003 Apr;17(7):1384-92.

PMID:
12713641
[PubMed - indexed for MEDLINE]
4.

Normal sensitivity to acute pain, but increased inflammatory hyperalgesia in mice lacking the nociceptin precursor polypeptide or the nociceptin receptor.

Depner UB, Reinscheid RK, Takeshima H, Brune K, Zeilhofer HU.

Eur J Neurosci. 2003 Jun;17(11):2381-7.

PMID:
12814369
[PubMed - indexed for MEDLINE]
5.

Involvement of nociceptin/orphanin FQ and its receptor in electroacupuncture-produced anti-hyperalgesia in rats with peripheral inflammation.

Fu X, Wang YQ, Wu GC.

Brain Res. 2006 Mar 17;1078(1):212-8. Epub 2006 Mar 24.

PMID:
16563360
[PubMed - indexed for MEDLINE]
6.

Involvement of NMDA receptor in nociceptive effects elicited by intrathecal [Tyr6] gamma2-MSH(6-12), and the interaction with nociceptin/orphanin FQ in pain modulation in mice.

Chang M, Li W, Peng YL, Gao YH, Yao J, Han RW, Wang R.

Brain Res. 2009 May 19;1271:36-48. doi: 10.1016/j.brainres.2009.03.041. Epub 2009 Mar 28.

PMID:
19332041
[PubMed - indexed for MEDLINE]
7.

Anti-allodynic and anti-hyperalgesic effects of nociceptin receptor antagonist, JTC-801, in rats after spinal nerve injury and inflammation.

Tamai H, Sawamura S, Takeda K, Orii R, Hanaoka K.

Eur J Pharmacol. 2005 Mar 14;510(3):223-8.

PMID:
15763246
[PubMed - indexed for MEDLINE]
8.

Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: pharmacological and genetic evidences.

Rizzi A, Nazzaro C, Marzola GG, Zucchini S, Trapella C, Guerrini R, Zeilhofer HU, Regoli D, Calo' G.

Pain. 2006 Sep;124(1-2):100-8. Epub 2006 May 11.

PMID:
16697109
[PubMed - indexed for MEDLINE]
9.

Characterization of nociceptin/orphanin FQ-induced pain responses in conscious mice: neonatal capsaicin treatment and N-methyl-D-aspartate receptor GluRepsilon subunit knockout mice.

Minami T, Okuda-Ashitaka E, Mori H, Sakimura K, Watanabe M, Mishina M, Ito S.

Neuroscience. 2000;97(1):133-42.

PMID:
10771345
[PubMed - indexed for MEDLINE]
10.

UFP-101 antagonizes the spinal antinociceptive effects of nociceptin/orphanin FQ: behavioral and electrophysiological studies in mice.

Nazzaro C, Rizzi A, Salvadori S, Guerrini R, Regoli D, Zeilhofer HU, Calo G.

Peptides. 2007 Mar;28(3):663-9. Epub 2006 Dec 11.

PMID:
17161885
[PubMed - indexed for MEDLINE]
11.

In vivo pain-inhibitory role of nociceptin/orphanin FQ in spinal cord.

Inoue M, Kawashima T, Takeshima H, Calo G, Inoue A, Nakata Y, Ueda H.

J Pharmacol Exp Ther. 2003 May;305(2):495-501. Epub 2003 Jan 24.

PMID:
12606680
[PubMed - indexed for MEDLINE]
Free Article
12.

The nociceptin receptor antagonist [Nphe1,Arg14,Lys15]nociceptin/orphanin FQ-NH2 blocks the stimulatory effects of nociceptin/orphanin FQ on the HPA axis in rats.

Leggett JD, Harbuz MS, Jessop DS, Fulford AJ.

Neuroscience. 2006 Sep 15;141(4):2051-7. Epub 2006 Jun 19.

PMID:
16784820
[PubMed - indexed for MEDLINE]
13.

Nocistatin: a novel neuropeptide encoded by the gene for the nociceptin/orphanin FQ precursor.

Okuda-Ashitaka E, Ito S.

Peptides. 2000 Jul;21(7):1101-9. Review.

PMID:
10998544
[PubMed - indexed for MEDLINE]
14.

Characterization of nociceptin hyperalgesia and allodynia in conscious mice.

Hara N, Minami T, Okuda-Ashitaka E, Sugimoto T, Sakai M, Onaka M, Mori H, Imanishi T, Shingu K, Ito S.

Br J Pharmacol. 1997 Jun;121(3):401-8.

PMID:
9179380
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Regulation of proinflammatory cytokines gene expression by nociceptin/orphanin FQ in the spinal cord and the cultured astrocytes.

Fu X, Zhu ZH, Wang YQ, Wu GC.

Neuroscience. 2007 Jan 5;144(1):275-85. Epub 2006 Oct 25.

PMID:
17069983
[PubMed - indexed for MEDLINE]
16.

Nociceptin/orphanin FQ (N/OFQ)-evoked bradycardia, hypotension, and diuresis are absent in N/OFQ peptide (NOP) receptor knockout mice.

Burmeister MA, Ansonoff MA, Pintar JE, Kapusta DR.

J Pharmacol Exp Ther. 2008 Sep;326(3):897-904. doi: 10.1124/jpet.107.135905. Epub 2008 Jun 6.

PMID:
18539652
[PubMed - indexed for MEDLINE]
Free Article
17.

Centrally administered nociceptin/orphanin FQ (N/OFQ) evokes bradycardia, hypotension, and diuresis in mice via activation of central N/OFQ peptide receptors.

Burmeister MA, Kapusta DR.

J Pharmacol Exp Ther. 2007 Jul;322(1):324-31. Epub 2007 Apr 23.

PMID:
17452419
[PubMed - indexed for MEDLINE]
Free Article
18.

Changes in expression of nociceptin/orphanin FQ and its receptor in spinal dorsal horn during electroacupuncture treatment for peripheral inflammatory pain in rats.

Fu X, Wang YQ, Wang J, Yu J, Wu GC.

Peptides. 2007 Jun;28(6):1220-8. Epub 2007 Apr 5.

PMID:
17493706
[PubMed - indexed for MEDLINE]
19.

Pharmacological profile of nociceptin/orphanin FQ receptors regulating 5-hydroxytryptamine release in the mouse neocortex.

Mela F, Marti M, Ulazzi L, Vaccari E, Zucchini S, Trapella C, Salvadori S, Beani L, Bianchi C, Morari M.

Eur J Neurosci. 2004 Mar;19(5):1317-24.

PMID:
15016089
[PubMed - indexed for MEDLINE]
20.

Modulation of synaptic transmission by nociceptin/orphanin FQ and nocistatin in the spinal cord dorsal horn of mutant mice lacking the nociceptin/orphanin FQ receptor.

Ahmadi S, Kotalla C, G├╝hring H, Takeshima H, Pahl A, Zeilhofer HU.

Mol Pharmacol. 2001 Mar;59(3):612-8.

PMID:
11179457
[PubMed - indexed for MEDLINE]
Free Article

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