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Results: 1 to 20 of 108

1.

STAT3 as a therapeutic target in head and neck cancer.

Leeman RJ, Lui VW, Grandis JR.

Expert Opin Biol Ther. 2006 Mar;6(3):231-41. Review.

PMID:
16503733
[PubMed - indexed for MEDLINE]
2.

Defining the role of the JAK-STAT pathway in head and neck and thoracic malignancies: implications for future therapeutic approaches.

Lai SY, Johnson FM.

Drug Resist Updat. 2010 Jun;13(3):67-78. doi: 10.1016/j.drup.2010.04.001. Epub 2010 May 14. Review.

PMID:
20471303
[PubMed - indexed for MEDLINE]
3.

A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas.

Lee TL, Yeh J, Friedman J, Yan B, Yang X, Yeh NT, Van Waes C, Chen Z.

Int J Cancer. 2008 May 1;122(9):1987-98. doi: 10.1002/ijc.23324.

PMID:
18172861
[PubMed - indexed for MEDLINE]
4.

In vivo antitumor efficacy of STAT3 blockade using a transcription factor decoy approach: implications for cancer therapy.

Xi S, Gooding WE, Grandis JR.

Oncogene. 2005 Feb 3;24(6):970-9.

PMID:
15592503
[PubMed - indexed for MEDLINE]
5.

Molecular cross-talk between the NFkappaB and STAT3 signaling pathways in head and neck squamous cell carcinoma.

Squarize CH, Castilho RM, Sriuranpong V, Pinto DS Jr, Gutkind JS.

Neoplasia. 2006 Sep;8(9):733-46.

PMID:
16984731
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Targeting the STAT pathway in head and neck cancer: recent advances and future prospects.

Nikitakis NG, Siavash H, Sauk JJ.

Curr Cancer Drug Targets. 2004 Dec;4(8):637-51. Review.

PMID:
15578920
[PubMed - indexed for MEDLINE]
7.

Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution.

Aggarwal BB, Sethi G, Ahn KS, Sandur SK, Pandey MK, Kunnumakkara AB, Sung B, Ichikawa H.

Ann N Y Acad Sci. 2006 Dec;1091:151-69. Review.

PMID:
17341611
[PubMed - indexed for MEDLINE]
8.

Dexamethasone treatment inhibits VEGF production via suppression of STAT3 in a head and neck cancer cell line.

Shim SH, Hah JH, Hwang SY, Heo DS, Sung MW.

Oncol Rep. 2010 Apr;23(4):1139-43.

PMID:
20204302
[PubMed - indexed for MEDLINE]
9.

The oncogenic effects of constitutive Stat3 signaling in salivary gland cancer cells are mediated by survivin and modulated by the NSAID sulindac.

Nikitakis NG, Scheper MA, Papanikolaou VS, Sauk JJ.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Jun;107(6):826-36. doi: 10.1016/j.tripleo.2008.12.054. Epub 2009 Mar 9.

PMID:
19272804
[PubMed - indexed for MEDLINE]
10.

Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1.

Lui VW, Boehm AL, Koppikar P, Leeman RJ, Johnson D, Ogagan M, Childs E, Freilino M, Grandis JR.

Mol Pharmacol. 2007 May;71(5):1435-43. Epub 2007 Feb 26.

PMID:
17325127
[PubMed - indexed for MEDLINE]
Free Article
11.

Targeting signal transducer and activator of transcription 3 with G-quartet oligonucleotides: a potential novel therapy for head and neck cancer.

Jing N, Zhu Q, Yuan P, Li Y, Mao L, Tweardy DJ.

Mol Cancer Ther. 2006 Feb;5(2):279-86.

PMID:
16505101
[PubMed - indexed for MEDLINE]
Free Article
12.

STAT signaling in head and neck cancer.

Song JI, Grandis JR.

Oncogene. 2000 May 15;19(21):2489-95. Review.

PMID:
10851047
[PubMed - indexed for MEDLINE]
Free Article
13.

The intracellular delivery of a recombinant peptide derived from the acidic domain of PIAS3 inhibits STAT3 transactivation and induces tumor cell death.

Borghouts C, Tittmann H, Delis N, Kirchenbauer M, Brill B, Groner B.

Mol Cancer Res. 2010 Apr;8(4):539-53. doi: 10.1158/1541-7786.MCR-09-0417. Epub 2010 Apr 6.

PMID:
20371673
[PubMed - indexed for MEDLINE]
Free Article
14.

Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma.

Jackson-Bernitsas DG, Ichikawa H, Takada Y, Myers JN, Lin XL, Darnay BG, Chaturvedi MM, Aggarwal BB.

Oncogene. 2007 Mar 1;26(10):1385-97. Epub 2006 Sep 4.

PMID:
16953224
[PubMed - indexed for MEDLINE]
15.

Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth.

Leong PL, Andrews GA, Johnson DE, Dyer KF, Xi S, Mai JC, Robbins PD, Gadiparthi S, Burke NA, Watkins SF, Grandis JR.

Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4138-43. Epub 2003 Mar 14.

PMID:
12640143
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Signal transducers and activators of transcription 3 up-regulates vascular endothelial growth factor production and tumor angiogenesis in head and neck squamous cell carcinoma.

Masuda M, Ruan HY, Ito A, Nakashima T, Toh S, Wakasaki T, Yasumatsu R, Kutratomi Y, Komune S, Weinstein IB.

Oral Oncol. 2007 Sep;43(8):785-90. Epub 2006 Dec 13.

PMID:
17169602
[PubMed - indexed for MEDLINE]
17.

Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide--interference with interferon-gamma-STAT1-mediated killing.

Tadlaoui Hbibi A, Laguillier C, Souissi I, Lesage D, Le Coquil S, Cao A, Metelev V, Baran-Marszak F, Fagard R.

FEBS J. 2009 May;276(9):2505-15. doi: 10.1111/j.1742-4658.2009.06975.x. Epub 2009 Mar 16.

PMID:
19476491
[PubMed - indexed for MEDLINE]
18.

Gene therapy for head and neck cancer.

Frank DK.

Surg Oncol Clin N Am. 2002 Jul;11(3):589-606, vi-vii. Review.

PMID:
12492081
[PubMed - indexed for MEDLINE]
19.

Active Stat3 is required for survival of human squamous cell carcinoma cells in serum-free conditions.

Yin W, Cheepala S, Roberts JN, Syson-Chan K, DiGiovanni J, Clifford JL.

Mol Cancer. 2006 Apr 7;5:15.

PMID:
16603078
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death.

Li C, Zang Y, Sen M, Leeman-Neill RJ, Man DS, Grandis JR, Johnson DE.

Mol Cancer Ther. 2009 Aug;8(8):2211-20. doi: 10.1158/1535-7163.MCT-09-0327. Epub 2009 Jul 28.

PMID:
19638453
[PubMed - indexed for MEDLINE]
Free PMC Article

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