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Results: 1 to 20 of 117

1.

Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins.

Okuda T, Tokuda N, Numata S, Ito M, Ohta M, Kawamura K, Wiels J, Urano T, Tajima O, Furukawa K, Furukawa K.

J Biol Chem. 2006 Apr 14;281(15):10230-5. Epub 2006 Feb 13.

PMID:
16476743
[PubMed - indexed for MEDLINE]
Free Article
2.

Murine glycosyltransferases responsible for the expression of globo-series glycolipids: cDNA structures, mRNA expression, and distribution of their products.

Fujii Y, Numata S, Nakamura Y, Honda T, Furukawa K, Urano T, Wiels J, Uchikawa M, Ozaki N, Matsuo S, Sugiura Y, Furukawa K.

Glycobiology. 2005 Dec;15(12):1257-67. Epub 2005 Aug 3.

PMID:
16079416
[PubMed - indexed for MEDLINE]
Free Article
3.

Molecular cloning of globotriaosylceramide/CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipids.

Kojima Y, Fukumoto S, Furukawa K, Okajima T, Wiels J, Yokoyama K, Suzuki Y, Urano T, Ohta M, Furukawa K.

J Biol Chem. 2000 May 19;275(20):15152-6.

PMID:
10748143
[PubMed - indexed for MEDLINE]
Free Article
4.

Expression of the Gb3/CD77 synthase gene in megakaryoblastic leukemia cells: implication in the sensitivity to verotoxins.

Furukawa K, Yokoyama K, Sato T, Wiels J, Hirayama Y, Ohta M, Furukawa K.

J Biol Chem. 2002 Mar 29;277(13):11247-54. Epub 2002 Jan 8.

PMID:
11782470
[PubMed - indexed for MEDLINE]
Free Article
5.

The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle.

Iwamura K, Furukawa K, Uchikawa M, Sojka BN, Kojima Y, Wiels J, Shiku H, Urano T, Furukawa K.

J Biol Chem. 2003 Nov 7;278(45):44429-38. Epub 2003 Jul 29.

PMID:
12888565
[PubMed - indexed for MEDLINE]
Free Article
6.

Inhibitory activity of Bifidobacterium longum HY8001 against Vero cytotoxin of Escherichia coli O157:H7.

Kim SH, Yang SJ, Koo HC, Bae WK, Kim JY, Park JH, Baek YJ, Park YH.

J Food Prot. 2001 Nov;64(11):1667-73.

PMID:
11726142
[PubMed - indexed for MEDLINE]
7.

Cloning of Gb3 synthase, the key enzyme in globo-series glycosphingolipid synthesis, predicts a family of alpha 1, 4-glycosyltransferases conserved in plants, insects, and mammals.

Keusch JJ, Manzella SM, Nyame KA, Cummings RD, Baenziger JU.

J Biol Chem. 2000 Aug 18;275(33):25315-21.

PMID:
10854428
[PubMed - indexed for MEDLINE]
Free Article
8.

Identification and characterization of the human Gb3/CD77 synthase gene promoter.

Okuda T, Nakayama K.

Glycobiology. 2008 Dec;18(12):1028-35. doi: 10.1093/glycob/cwn082. Epub 2008 Aug 29.

PMID:
18757779
[PubMed - indexed for MEDLINE]
Free Article
9.

Neuronal apoptosis and inflammatory responses in the central nervous system of a rabbit treated with Shiga toxin-2.

Takahashi K, Funata N, Ikuta F, Sato S.

J Neuroinflammation. 2008 Mar 21;5:11. doi: 10.1186/1742-2094-5-11.

PMID:
18355415
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Two distinct Gb3/CD77 signaling pathways leading to apoptosis are triggered by anti-Gb3/CD77 mAb and verotoxin-1.

Tétaud C, Falguières T, Carlier K, Lécluse Y, Garibal J, Coulaud D, Busson P, Steffensen R, Clausen H, Johannes L, Wiels J.

J Biol Chem. 2003 Nov 14;278(46):45200-8. Epub 2003 Aug 27.

PMID:
12944404
[PubMed - indexed for MEDLINE]
Free Article
11.

Fabry disease in mice protects against lethal disease caused by Shiga toxin-expressing enterohemorrhagic Escherichia coli.

Cilmi SA, Karalius BJ, Choy W, Smith RN, Butterton JR.

J Infect Dis. 2006 Oct 15;194(8):1135-40. Epub 2006 Sep 8.

PMID:
16991089
[PubMed - indexed for MEDLINE]
Free Article
12.

Verotoxin 1 from Escherichia coli affects Gb3/CD77+ bovine lymphocytes independent of interleukin-2, tumor necrosis factor-alpha, and interferon-alpha.

Menge C, Stamm I, Blessenohl M, Wieler LH, Baljer G.

Exp Biol Med (Maywood). 2003 Apr;228(4):377-86.

PMID:
12671182
[PubMed - indexed for MEDLINE]
13.

Molecular basis for high renal cell sensitivity to the cytotoxic effects of shigatoxin-1: upregulation of globotriaosylceramide expression.

Hughes AK, Ergonul Z, Stricklett PK, Kohan DE.

J Am Soc Nephrol. 2002 Sep;13(9):2239-45. Erratum in: J Am Soc Nephrol. 2003 May;14(5):following table of contents. Ergonal, Z [corrected to Ergonul, Z].

PMID:
12191968
[PubMed - indexed for MEDLINE]
Free Article
14.

Endothelial heterogeneity in Shiga toxin receptors and responses.

Obrig TG, Louise CB, Lingwood CA, Boyd B, Barley-Maloney L, Daniel TO.

J Biol Chem. 1993 Jul 25;268(21):15484-8.

PMID:
8340376
[PubMed - indexed for MEDLINE]
Free Article
15.

Glycosphingolipids in vascular endothelial cells: relationship of heterogeneity in Gb3Cer/CD77 receptor expression with differential Shiga toxin 1 cytotoxicity.

Schweppe CH, Bielaszewska M, Pohlentz G, Friedrich AW, Büntemeyer H, Schmidt MA, Kim KS, Peter-Katalinić J, Karch H, Müthing J.

Glycoconj J. 2008 May;25(4):291-304. doi: 10.1007/s10719-007-9091-7. Epub 2008 Jan 5.

PMID:
18176841
[PubMed - indexed for MEDLINE]
16.

Recruitment of renal tubular epithelial cells expressing verotoxin-1 (Stx1) receptors in HIV-1 transgenic mice with renal disease.

Liu XH, Lingwood CA, Ray PE.

Kidney Int. 1999 Feb;55(2):554-61.

PMID:
9987079
[PubMed - indexed for MEDLINE]
Free Article
17.

A single point mutation in the gene encoding Gb3/CD77 synthase causes a rare inherited polyagglutination syndrome.

Suchanowska A, Kaczmarek R, Duk M, Lukasiewicz J, Smolarek D, Majorczyk E, Jaskiewicz E, Laskowska A, Wasniowska K, Grodecka M, Lisowska E, Czerwinski M.

J Biol Chem. 2012 Nov 2;287(45):38220-30. doi: 10.1074/jbc.M112.408286. Epub 2012 Sep 10. Erratum in: J Biol Chem. 2013 Jan 4;288(1):294.

PMID:
22965229
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Efficient generation of useful monoclonal antibodies reactive with globotriaosylceramide using knockout mice lacking Gb3/CD77 synthase.

Kondo Y, Tokuda N, Furukawa K, Ando R, Uchikawa M, Zhang Q, Xiaoyan F, Furukawa K.

Glycoconj J. 2011 Aug;28(6):371-84. doi: 10.1007/s10719-011-9335-4. Epub 2011 Jun 10.

PMID:
21660412
[PubMed - indexed for MEDLINE]
19.

Inhibition of Vero cell cytotoxic activity in Escherichia coli O157:H7 lysates by globotriaosylceramide, Gb3, from bovine milk.

Watarai S, Tana, Inoue K, Kushi Y, Isogai E, Yokota K, Naka K, Oguma K, Kodama H.

Biosci Biotechnol Biochem. 2001 Feb;65(2):414-9.

PMID:
11302178
[PubMed - indexed for MEDLINE]
Free Article
20.

An in vitro model of Fabry disease.

Shu L, Murphy HS, Cooling L, Shayman JA.

J Am Soc Nephrol. 2005 Sep;16(9):2636-45. Epub 2005 Jul 20.

PMID:
16033856
[PubMed - indexed for MEDLINE]
Free Article

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