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Items: 1 to 20 of 86

1.

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells.

Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, Abraham J, Lederman MM, Benito JM, Goepfert PA, Connors M, Roederer M, Koup RA.

Blood. 2006 Jun 15;107(12):4781-9. Epub 2006 Feb 7.

2.

HIV-1-infected children on HAART: immunologic features of three different levels of viral suppression.

Zaccarelli-Filho CA, Ono E, Machado DM, Brunialti M, Succi RC, Salomão R, Kallás EG, de Moraes-Pinto MI.

Cytometry B Clin Cytom. 2007 Jan 15;72(1):14-21.

3.

Preservation of T cell proliferation restricted by protective HLA alleles is critical for immune control of HIV-1 infection.

Horton H, Frank I, Baydo R, Jalbert E, Penn J, Wilson S, McNevin JP, McSweyn MD, Lee D, Huang Y, De Rosa SC, McElrath MJ.

J Immunol. 2006 Nov 15;177(10):7406-15.

4.

Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity.

Propato A, Schiaffella E, Vicenzi E, Francavilla V, Baloni L, Paroli M, Finocchi L, Tanigaki N, Ghezzi S, Ferrara R, Chesnut R, Livingston B, Sette A, Paganelli R, Aiuti F, Poli G, Barnaba V.

Hum Immunol. 2001 Jun;62(6):561-76.

PMID:
11390031
5.

Suppression of viral replication with highly active antiretroviral therapy has no impact on the functional profile of HIV-specific CD8(+) T cells.

López M, Soriano V, Rallón N, Cascajero A, González-Lahoz J, Benito JM.

Eur J Immunol. 2008 Jun;38(6):1548-58. doi: 10.1002/eji.200738054.

6.

Correlation between gag-specific CD8 T-cell responses, viral load, and CD4 count in HIV-1 infection is dependent on disease status.

Jiao Y, Xie J, Li T, Han Y, Qiu Z, Zuo L, Wang A.

J Acquir Immune Defic Syndr. 2006 Jul;42(3):263-8.

PMID:
16763520
7.

Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control.

Hersperger AR, Pereyra F, Nason M, Demers K, Sheth P, Shin LY, Kovacs CM, Rodriguez B, Sieg SF, Teixeira-Johnson L, Gudonis D, Goepfert PA, Lederman MM, Frank I, Makedonas G, Kaul R, Walker BD, Betts MR.

PLoS Pathog. 2010 May 27;6(5):e1000917. doi: 10.1371/journal.ppat.1000917.

8.

PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors.

Zhang JY, Zhang Z, Wang X, Fu JL, Yao J, Jiao Y, Chen L, Zhang H, Wei J, Jin L, Shi M, Gao GF, Wu H, Wang FS.

Blood. 2007 Jun 1;109(11):4671-8. Epub 2007 Feb 1.

9.

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors.

Migueles SA, Laborico AC, Shupert WL, Sabbaghian MS, Rabin R, Hallahan CW, Van Baarle D, Kostense S, Miedema F, McLaughlin M, Ehler L, Metcalf J, Liu S, Connors M.

Nat Immunol. 2002 Nov;3(11):1061-8. Epub 2002 Oct 7.

PMID:
12368910
10.

Phenotypic and functional analysis of immune CD8+ T cell responses induced by a single injection of a HIV DNA vaccine in mice.

Arrode G, Hegde R, Mani A, Jin Y, Chebloune Y, Narayan O.

J Immunol. 2007 Feb 15;178(4):2318-27.

11.

Antiretroviral therapy initiation during primary HIV infection enhances both CD127 expression and the proliferative capacity of HIV-specific CD8+ T cells.

Lécuroux C, Girault I, Boutboul F, Urrutia A, Goujard C, Meyer L, Lambotte O, Chaix ML, Martinez V, Autran B, Sinet M, Venet A; ANRS PRIMO Cohort, ANRS HIC Study Group; ANRS ALT Cohort; ANRS HIC Study Group.

AIDS. 2009 Aug 24;23(13):1649-58. doi: 10.1097/QAD.0b013e32832e6634.

PMID:
19617814
12.

Detection of polyfunctional Mycobacterium tuberculosis-specific T cells and association with viral load in HIV-1-infected persons.

Day CL, Mkhwanazi N, Reddy S, Mncube Z, van der Stok M, Klenerman P, Walker BD.

J Infect Dis. 2008 Apr 1;197(7):990-9. doi: 10.1086/529048.

13.

HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype.

Sáez-Cirión A, Lacabaratz C, Lambotte O, Versmisse P, Urrutia A, Boufassa F, Barré-Sinoussi F, Delfraissy JF, Sinet M, Pancino G, Venet A; Agence Nationale de Recherches sur le Sida EP36 HIV Controllers Study Group.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6776-81. Epub 2007 Apr 11.

14.

Functional T cell subsets contribute differentially to HIV peptide-specific responses within infected individuals: correlation of these functional T cell subsets with markers of disease progression.

Peretz Y, Ndongala ML, Boulet S, Boulassel MR, Rouleau D, Côté P, Longpré D, Routy JP, Falutz J, Tremblay C, Tsoukas CM, Sékaly RP, Bernard NF.

Clin Immunol. 2007 Jul;124(1):57-68. Epub 2007 May 22.

PMID:
17521962
15.

IL-7Ralpha expression on CD4+ T lymphocytes decreases with HIV disease progression and inversely correlates with immune activation.

Koesters SA, Alimonti JB, Wachihi C, Matu L, Anzala O, Kimani J, Embree JE, Plummer FA, Fowke KR.

Eur J Immunol. 2006 Feb;36(2):336-44.

16.

The functional CD8 T cell response to HIV becomes type-specific in progressive disease.

Lee SK, Xu Z, Lieberman J, Shankar P.

J Clin Invest. 2002 Nov;110(9):1339-47.

17.

Memory CD8(+) T cells elicited by HIV-1 lipopeptide vaccines display similar phenotypic profiles but differences in term of magnitude and multifunctionality compared with FLU- or EBV-specific memory T cells in humans.

Figueiredo S, Charmeteau B, Surenaud M, Salmon D, Launay O, Guillet JG, Hosmalin A, Gahery H.

Vaccine. 2014 Jan 16;32(4):492-501. doi: 10.1016/j.vaccine.2013.11.052. Epub 2013 Nov 27.

PMID:
24291199
18.

Antigen burden is major determinant of human immunodeficiency virus-specific CD8+ T cell maturation state: potential implications for therapeutic immunization.

Tussey LG, Nair US, Bachinsky M, Edwards BH, Bakari J, Grimm K, Joyce J, Vessey R, Steigbigel R, Robertson MN, Shiver JW, Goepfert PA.

J Infect Dis. 2003 Feb 1;187(3):364-74. Epub 2003 Jan 24.

19.

The adjuvancy of OX40 ligand (CD252) on an HIV-1 canarypox vaccine.

Liu J, Ngai N, Stone GW, Yue FY, Ostrowski MA.

Vaccine. 2009 Aug 13;27(37):5077-84. doi: 10.1016/j.vaccine.2009.06.046. Epub 2009 Jun 30.

PMID:
19573639
20.

CD4(+) T-cell immunodeficiency is more dependent on immune activation than viral load in HIV-infected children on highly active antiretroviral therapy.

Resino S, Seoane E, Gutiérrez MD, León JA, Muñoz-Fernández MA.

J Acquir Immune Defic Syndr. 2006 Jul;42(3):269-76.

PMID:
16810122
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