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Results: 1 to 20 of 82

1.

The competing roles of virus replication and hepatocyte death rates in the emergence of drug-resistant mutants: theoretical considerations.

Litwin S, Toll E, Jilbert AR, Mason WS.

J Clin Virol. 2005 Dec;34 Suppl 1:S96-S107.

PMID:
16461233
[PubMed - indexed for MEDLINE]
2.

Evaluation of novel strategies to combat hepatitis B virus targetting wild-type and drug-resistant mutants in experimental models.

Zoulim F.

Antivir Chem Chemother. 2001;12 Suppl 1:131-42. Review.

PMID:
11594680
[PubMed - indexed for MEDLINE]
3.

Replication of naturally occurring woodchuck hepatitis virus deletion mutants in primary hepatocyte cultures and after transmission to naive woodchucks.

Lu M, Hilken G, Yang D, Kemper T, Roggendorf M.

J Virol. 2001 Apr;75(8):3811-8.

PMID:
11264370
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Supportive role played by precore and preS2 genomic changes in the establishment of lamivudine-resistant hepatitis B virus.

Ohkawa K, Takehara T, Kato M, Deguchi M, Kagita M, Hikita H, Sasakawa A, Kohga K, Uemura A, Sakamori R, Yamaguchi S, Miyagi T, Ishida H, Tatsumi T, Hayashi N.

J Infect Dis. 2008 Oct 15;198(8):1150-8. doi: 10.1086/591941.

PMID:
18713056
[PubMed - indexed for MEDLINE]
Free Article
5.

Major causes of antiviral drug resistance and implications for treatment of hepatitis B virus monoinfection and coinfection with HIV.

Locarnini S, Warner N.

Antivir Ther. 2007;12 Suppl 3:H15-23. Review.

PMID:
18284179
[PubMed - indexed for MEDLINE]
6.

The high incidence of the emergence of entecavir-resistant mutants among patients infected with lamivudine-resistant hepatitis B virus.

Nagasaki F, Niitsuma H, Ueno Y, Inoue J, Kogure T, Fukushima K, Shimosegawa T.

Tohoku J Exp Med. 2007 Oct;213(2):181-6.

PMID:
17917412
[PubMed - indexed for MEDLINE]
Free Article
7.

Rapid quantitation of lamivudine-resistant mutants in lamivudine treated and untreated patients with chronic hepatitis B virus infection.

Shi M, Yang ZJ, Wang RS, Zhang H, Zhu YF, Xu YP, Lin QY, Jin LJ.

Clin Chim Acta. 2006 Nov;373(1-2):172-5. Epub 2006 May 22.

PMID:
16814763
[PubMed - indexed for MEDLINE]
8.

Rolling circle amplification, a powerful tool for genetic and functional studies of complete hepatitis B virus genomes from low-level infections and for directly probing covalently closed circular DNA.

Margeridon S, Carrouée-Durantel S, Chemin I, Barraud L, Zoulim F, Trépo C, Kay A.

Antimicrob Agents Chemother. 2008 Sep;52(9):3068-73. doi: 10.1128/AAC.01318-07. Epub 2008 Jul 7.

PMID:
18606836
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Evolution of multi-drug resistant hepatitis B virus during sequential therapy.

Yim HJ, Hussain M, Liu Y, Wong SN, Fung SK, Lok AS.

Hepatology. 2006 Sep;44(3):703-12.

PMID:
16941700
[PubMed - indexed for MEDLINE]
10.

The clinical impact of early detection of the YMDD mutant on the outcomes of long-term lamivudine therapy in patients with chronic hepatitis B.

Paik YH, Han KH, Hong SP, Lee HW, Lee KS, Kim SO, Shin JE, Ahn SH, Chon CY, Moon YM.

Antivir Ther. 2006;11(4):447-55.

PMID:
16856618
[PubMed - indexed for MEDLINE]
11.

Early detection and quantification of lamivudine-resistant hepatitis B virus mutants by fluorescent biprobe hybridization assay in lamivudine-treated patients.

Umeoka F, Iwasaki Y, Matsumura M, Takaki A, Kobashi H, Tatsukawa M, Shiraha H, Fujioka S, Sakaguchi K, Shiratori Y.

J Gastroenterol. 2006 Jul;41(7):693-701.

PMID:
16933008
[PubMed - indexed for MEDLINE]
12.

Initiation of hepatitis B virus genome replication and production of infectious virus following delivery in HepG2 cells by novel recombinant baculovirus vector.

Lucifora J, Durantel D, Belloni L, Barraud L, Villet S, Vincent IE, Margeridon-Thermet S, Hantz O, Kay A, Levrero M, Zoulim F.

J Gen Virol. 2008 Aug;89(Pt 8):1819-28. doi: 10.1099/vir.0.83659-0.

PMID:
18632952
[PubMed - indexed for MEDLINE]
Free Article
13.

Prolonged persistence of lamivudine-resistant mutant and emergence of new lamivudine-resistant mutants two years after lamivudine withdrawal in HBsAg-positive chronic hepatitis patient: a case report.

Orlando R, Tosone G, Portella G, Veropalumbo E, D'Onofrio M, Piazza M.

Infection. 2008 Oct;36(5):472-4. Epub 2007 Oct 25.

PMID:
17962902
[PubMed - indexed for MEDLINE]
14.
15.

Direct cytopathic effects of particular hepatitis B virus genotypes in severe combined immunodeficiency transgenic with urokinase-type plasminogen activator mouse with human hepatocytes.

Sugiyama M, Tanaka Y, Kurbanov F, Maruyama I, Shimada T, Takahashi S, Shirai T, Hino K, Sakaida I, Mizokami M.

Gastroenterology. 2009 Feb;136(2):652-62.e3. doi: 10.1053/j.gastro.2008.10.048. Epub 2008 Oct 29.

PMID:
19041311
[PubMed - indexed for MEDLINE]
16.

Efficacy of hepatitis B vaccine against antiviral drug-resistant hepatitis B virus mutants in the chimpanzee model.

Kamili S, Sozzi V, Thompson G, Campbell K, Walker CM, Locarnini S, Krawczynski K.

Hepatology. 2009 May;49(5):1483-91. doi: 10.1002/hep.22796.

PMID:
19274751
[PubMed - indexed for MEDLINE]
17.

Molecular mechanisms of resistance to antiviral therapy in patients with chronic hepatitis B.

Yuan HJ, Lee WM.

Curr Mol Med. 2007 Mar;7(2):185-97. Review.

PMID:
17346170
[PubMed - indexed for MEDLINE]
18.

Intrahepatic levels and replicative activity of covalently closed circular hepatitis B virus DNA in chronically infected patients.

Laras A, Koskinas J, Dimou E, Kostamena A, Hadziyannis SJ.

Hepatology. 2006 Sep;44(3):694-702.

PMID:
16941694
[PubMed - indexed for MEDLINE]
19.

Mutational patterns of hepatitis B virus genome and clinical outcomes after emergence of drug-resistant variants during lamivudine therapy: analyses of the polymerase gene and full-length sequences.

Enomoto M, Tamori A, Kohmoto MT, Morikawa H, Habu D, Sakaguchi H, Takeda T, Seki S, Kawada N, Shiomi S, Nishiguchi S.

J Med Virol. 2007 Nov;79(11):1664-70.

PMID:
17854034
[PubMed - indexed for MEDLINE]
20.

Antiviral-resistant hepatitis B virus: can we prevent this monster from growing?

Zoulim F, Buti M, Lok AS.

J Viral Hepat. 2007 Nov;14 Suppl 1:29-36. Review.

PMID:
17958640
[PubMed - indexed for MEDLINE]

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