Similar articles for PMID: 16451072

Year	Number of Results
1967	1
1988	1
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2001	3
2002	3
2003	4
2004	22
2005	15
2006	29
2007	27
2008	24
2009	9
2010	10
2011	5
2012	8
2013	6
2014	1
2016	1
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2024	0

1

Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K.

Crane SN, Black WC, Palmer JT, Davis DE, Setti E, Robichaud J, Paquet J, Oballa RM, Bayly CI, McKay DJ, Somoza JR, Chauret N, Seto C, Scheigetz J, Wesolowski G, Massé F, Desmarais S, Ouellet M. Crane SN, et al. J Med Chem. 2006 Feb 9;49(3):1066-79. doi: 10.1021/jm051059p. J Med Chem. 2006. PMID: 16451072

2

Beta-substituted cyclohexanecarboxamide cathepsin K inhibitors: modification of the 1,2-disubstituted aromatic core.

Robichaud J, Bayly CI, Black WC, Desmarais S, Léger S, Massé F, McKay DJ, Oballa RM, Pâquet J, Percival MD, Truchon JF, Wesolowski G, Crane SN. Robichaud J, et al. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3146-51. doi: 10.1016/j.bmcl.2007.03.028. Epub 2007 Mar 15. Bioorg Med Chem Lett. 2007. PMID: 17408953

3

Design of potent, selective, and orally bioavailable inhibitors of cysteine protease cathepsin k.

Tavares FX, Boncek V, Deaton DN, Hassell AM, Long ST, Miller AB, Payne AA, Miller LR, Shewchuk LM, Wells-Knecht K, Willard DH Jr, Wright LL, Zhou HQ. Tavares FX, et al. J Med Chem. 2004 Jan 29;47(3):588-99. doi: 10.1021/jm030373l. J Med Chem. 2004. PMID: 14736240

4

Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method.

Patterson AW, Wood WJ, Hornsby M, Lesley S, Spraggon G, Ellman JA. Patterson AW, et al. J Med Chem. 2006 Oct 19;49(21):6298-307. doi: 10.1021/jm060701s. J Med Chem. 2006. PMID: 17034136

5

P2-P3 conformationally constrained ketoamide-based inhibitors of cathepsin K.

Barrett DG, Boncek VM, Catalano JG, Deaton DN, Hassell AM, Jurgensen CH, Long ST, McFadyen RB, Miller AB, Miller LR, Payne JA, Ray JA, Samano V, Shewchuk LM, Tavares FX, Wells-Knecht KJ, Willard DH Jr, Wright LL, Zhou HQ. Barrett DG, et al. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3540-6. doi: 10.1016/j.bmcl.2005.05.062. Bioorg Med Chem Lett. 2005. PMID: 15982880

6

Potent and selective P2-P3 ketoamide inhibitors of cathepsin K with good pharmacokinetic properties via favorable P1', P1, and/or P3 substitutions.

Barrett DG, Catalano JG, Deaton DN, Hassell AM, Long ST, Miller AB, Miller LR, Shewchuk LM, Wells-Knecht KJ, Willard DH Jr, Wright LL. Barrett DG, et al. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4897-902. doi: 10.1016/j.bmcl.2004.07.031. Bioorg Med Chem Lett. 2004. PMID: 15341947

7

Design and synthesis of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 1.

Liu H, Tully DC, Epple R, Bursulaya B, Li J, Harris JL, Williams JA, Russo R, Tumanut C, Roberts MJ, Alper PB, He Y, Karanewsky DS. Liu H, et al. Bioorg Med Chem Lett. 2005 Nov 15;15(22):4979-84. doi: 10.1016/j.bmcl.2005.08.017. Epub 2005 Sep 23. Bioorg Med Chem Lett. 2005. PMID: 16183279

8

Orally bioavailable small molecule ketoamide-based inhibitors of cathepsin K.

Barrett DG, Catalano JG, Deaton DN, Long ST, Miller LR, Tavares FX, Wells-Knecht KJ, Wright LL, Zhou HQ. Barrett DG, et al. Bioorg Med Chem Lett. 2004 May 17;14(10):2543-6. doi: 10.1016/j.bmcl.2004.02.085. Bioorg Med Chem Lett. 2004. PMID: 15109647

9

Structure activity relationships of 5-, 6-, and 7-methyl-substituted azepan-3-one cathepsin K inhibitors.

Yamashita DS, Marquis RW, Xie R, Nidamarthy SD, Oh HJ, Jeong JU, Erhard KF, Ward KW, Roethke TJ, Smith BR, Cheng HY, Geng X, Lin F, Offen PH, Wang B, Nevins N, Head MS, Haltiwanger RC, Narducci Sarjeant AA, Liable-Sands LM, Zhao B, Smith WW, Janson CA, Gao E, Tomaszek T, McQueney M, James IE, Gress CJ, Zembryki DL, Lark MW, Veber DF. Yamashita DS, et al. J Med Chem. 2006 Mar 9;49(5):1597-612. doi: 10.1021/jm050915u. J Med Chem. 2006. PMID: 16509577

10

Potent and selective ketoamide-based inhibitors of cysteine protease, cathepsin K.

Tavares FX, Deaton DN, Miller AB, Miller LR, Wright LL, Zhou HQ. Tavares FX, et al. J Med Chem. 2004 Oct 7;47(21):5049-56. doi: 10.1021/jm0400799. J Med Chem. 2004. PMID: 15456248

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