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Results: 1 to 20 of 106

1.

Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia.

Haramis AP, Hurlstone A, van der Velden Y, Begthel H, van den Born M, Offerhaus GJ, Clevers HC.

EMBO Rep. 2006 Apr;7(4):444-9. Epub 2006 Jan 27.

PMID:
16439994
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Up-regulation of CYP26A1 in adenomatous polyposis coli-deficient vertebrates via a WNT-dependent mechanism: implications for intestinal cell differentiation and colon tumor development.

Shelton DN, Sandoval IT, Eisinger A, Chidester S, Ratnayake A, Ireland CM, Jones DA.

Cancer Res. 2006 Aug 1;66(15):7571-7.

PMID:
16885356
[PubMed - indexed for MEDLINE]
Free Article
3.

The Wnt/beta-catenin pathway regulates cardiac valve formation.

Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H.

Nature. 2003 Oct 9;425(6958):633-7.

PMID:
14534590
[PubMed - indexed for MEDLINE]
Free Article
4.

A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.

Gaspar C, Franken P, Molenaar L, Breukel C, van der Valk M, Smits R, Fodde R.

PLoS Genet. 2009 Jul;5(7):e1000547. doi: 10.1371/journal.pgen.1000547. Epub 2009 Jul 3.

PMID:
19578404
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia.

Senda T, Iizuka-Kogo A, Onouchi T, Shimomura A.

Med Mol Morphol. 2007 Jun;40(2):68-81. Epub 2007 Jun 18. Review.

PMID:
17572842
[PubMed - indexed for MEDLINE]
6.

Adenomatous polyposis coli control of C-terminal binding protein-1 stability regulates expression of intestinal retinol dehydrogenases.

Nadauld LD, Phelps R, Moore BC, Eisinger A, Sandoval IT, Chidester S, Peterson PW, Manos EJ, Sklow B, Burt RW, Jones DA.

J Biol Chem. 2006 Dec 8;281(49):37828-35. Epub 2006 Oct 6.

PMID:
17028196
[PubMed - indexed for MEDLINE]
Free Article
7.

Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations.

Segditsas S, Sieber OM, Rowan A, Setien F, Neale K, Phillips RK, Ward R, Esteller M, Tomlinson IP.

Exp Mol Pathol. 2008 Dec;85(3):201-6. doi: 10.1016/j.yexmp.2008.09.006. Epub 2008 Oct 11.

PMID:
18977219
[PubMed - indexed for MEDLINE]
8.

Loss of adenomatous polyposis coli (apc) results in an expanded ciliary marginal zone in the zebrafish eye.

Stephens WZ, Senecal M, Nguyen M, Piotrowski T.

Dev Dyn. 2010 Jul;239(7):2066-77. doi: 10.1002/dvdy.22325.

PMID:
20549742
[PubMed - indexed for MEDLINE]
Free Article
9.

APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression.

Janssen KP, Alberici P, Fsihi H, Gaspar C, Breukel C, Franken P, Rosty C, Abal M, El Marjou F, Smits R, Louvard D, Fodde R, Robine S.

Gastroenterology. 2006 Oct;131(4):1096-109. Epub 2006 Aug 16. Erratum in: Gastroenterology. 2006 Dec;131(6):2029.

PMID:
17030180
[PubMed - indexed for MEDLINE]
10.

The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15.

Huang X, Langelotz C, Hetfeld-Pechoc BK, Schwenk W, Dubiel W.

J Mol Biol. 2009 Aug 28;391(4):691-702. doi: 10.1016/j.jmb.2009.06.066. Epub 2009 Jul 1.

PMID:
19576224
[PubMed - indexed for MEDLINE]
11.

Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish.

Valvezan AJ, Huang J, Lengner CJ, Pack M, Klein PS.

Dis Model Mech. 2014 Jan;7(1):63-71. doi: 10.1242/dmm.012625. Epub 2013 Oct 2.

PMID:
24092877
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Adenomatous polyposis coli alteration in digestive endocrine tumours: correlation with nuclear translocation of beta-catenin and chromosomal instability.

Pizzi S, Azzoni C, Tamburini E, Bottarelli L, Campanini N, D'Adda T, Fellegara G, Luong TV, Pasquali C, Rossi G, Delle Fave G, Camisa R, Bordi C, Rindi G.

Endocr Relat Cancer. 2008 Dec;15(4):1013-24. doi: 10.1677/ERC-07-0230. Epub 2008 Jul 16.

PMID:
18632876
[PubMed - indexed for MEDLINE]
Free Article
13.

[Expression and significance of APC, beta-catenin, C-myc, and Cyclin D1 proteins in colorectal carcinoma].

Dai WB, Ren ZP, Chen WL, DU J, Shi Z, Tang DY.

Ai Zheng. 2007 Sep;26(9):963-6. Chinese.

PMID:
17927853
[PubMed - indexed for MEDLINE]
14.

Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes.

Cullingworth J, Hooper ML, Harrison DJ, Mason JO, Sirard C, Patek CE, Clarke AR.

Oncogene. 2002 Jul 11;21(30):4696-701.

PMID:
12096346
[PubMed - indexed for MEDLINE]
Free Article
15.

Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours.

Kohler EM, Chandra SH, Behrens J, Schneikert J.

Hum Mol Genet. 2009 Jan 15;18(2):213-26. doi: 10.1093/hmg/ddn338. Epub 2008 Oct 14.

PMID:
18854359
[PubMed - indexed for MEDLINE]
Free Article
16.

Connexin43 is overexpressed in Apc(Min/+)-mice adenomas and colocalises with COX-2 in myofibroblasts.

Husøy T, Knutsen HK, Cruciani V, Olstørn HB, Mikalsen SO, Løberg EM, Alexander J.

Int J Cancer. 2005 Sep 1;116(3):351-8.

PMID:
15800939
[PubMed - indexed for MEDLINE]
17.

Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer.

Nagel R, le Sage C, Diosdado B, van der Waal M, Oude Vrielink JA, Bolijn A, Meijer GA, Agami R.

Cancer Res. 2008 Jul 15;68(14):5795-802. doi: 10.1158/0008-5472.CAN-08-0951.

PMID:
18632633
[PubMed - indexed for MEDLINE]
Free Article
18.

The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid.

Eisinger AL, Nadauld LD, Shelton DN, Peterson PW, Phelps RA, Chidester S, Stafforini DM, Prescott SM, Jones DA.

J Biol Chem. 2006 Jul 21;281(29):20474-82. Epub 2006 May 14.

PMID:
16699180
[PubMed - indexed for MEDLINE]
Free Article
19.

Chromosomal instability by beta-catenin/TCF transcription in APC or beta-catenin mutant cells.

Aoki K, Aoki M, Sugai M, Harada N, Miyoshi H, Tsukamoto T, Mizoshita T, Tatematsu M, Seno H, Chiba T, Oshima M, Hsieh CL, Taketo MM.

Oncogene. 2007 May 24;26(24):3511-20. Epub 2006 Dec 11.

PMID:
17160019
[PubMed - indexed for MEDLINE]
20.

Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC.

Näthke I.

Nat Rev Cancer. 2006 Dec;6(12):967-74. Epub 2006 Nov 9. Review.

PMID:
17093505
[PubMed - indexed for MEDLINE]
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