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Comparison of live and inactivated tick-borne encephalitis virus vaccines for safety, immunogenicity and efficacy in rhesus monkeys.

Rumyantsev AA, Chanock RM, Murphy BR, Pletnev AG.

Vaccine. 2006 Jan 12;24(2):133-43. Epub 2005 Aug 9.

PMID:
16115704
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Insertion of microRNA targets into the flavivirus genome alters its highly neurovirulent phenotype.

Heiss BL, Maximova OA, Pletnev AG.

J Virol. 2011 Feb;85(4):1464-72. doi: 10.1128/JVI.02091-10. Epub 2010 Dec 1.

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Chimeric Langat/Dengue viruses protect mice from heterologous challenge with the highly virulent strains of tick-borne encephalitis virus.

Pletnev AG, Karganova GG, Dzhivanyan TI, Lashkevich VA, Bray M.

Virology. 2000 Aug 15;274(1):26-31.

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A BHK-21 cell culture-adapted tick-borne encephalitis virus mutant is attenuated for neuroinvasiveness.

Goto A, Hayasaka D, Yoshii K, Mizutani T, Kariwa H, Takashima I.

Vaccine. 2003 Sep 8;21(25-26):4043-51.

PMID:
12922141
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The neurovirulence and neuroinvasiveness of chimeric tick-borne encephalitis/dengue virus can be attenuated by introducing defined mutations into the envelope and NS5 protein genes and the 3' non-coding region of the genome.

Engel AR, Rumyantsev AA, Maximova OA, Speicher JM, Heiss B, Murphy BR, Pletnev AG.

Virology. 2010 Sep 15;405(1):243-52. doi: 10.1016/j.virol.2010.06.014. Epub 2010 Jul 1.

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Evaluation of the Langat/dengue 4 chimeric virus as a live attenuated tick-borne encephalitis vaccine for safety and immunogenicity in healthy adult volunteers.

Wright PF, Ankrah S, Henderson SE, Durbin AP, Speicher J, Whitehead SS, Murphy BR, Pletnev AG.

Vaccine. 2008 Feb 13;26(7):882-90. doi: 10.1016/j.vaccine.2007.12.015. Epub 2008 Jan 4.

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Construction and characterization of chimeric tick-borne encephalitis/dengue type 4 viruses.

Pletnev AG, Bray M, Huggins J, Lai CJ.

Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10532-6.

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Safety evaluation of chimeric Langat/Dengue 4 flavivirus, a live vaccine candidate against tick-borne encephalitis.

Pripuzova NS, Tereshkina NV, Gmyl LV, Dzhivanyan TI, Rumyantsev AA, Romanova LIu, Mustafina AN, Lashkevich VA, Karganova GG.

J Med Virol. 2009 Oct;81(10):1777-85. doi: 10.1002/jmv.21587.

PMID:
19697399
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