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Results: 1 to 20 of 439

1.

IgG-assisted age-dependent clearance of Alzheimer's amyloid beta peptide by the blood-brain barrier neonatal Fc receptor.

Deane R, Sagare A, Hamm K, Parisi M, LaRue B, Guo H, Wu Z, Holtzman DM, Zlokovic BV.

J Neurosci. 2005 Dec 14;25(50):11495-503.

PMID:
16354907
[PubMed - indexed for MEDLINE]
Free Article
2.

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, Xu F, Parisi M, LaRue B, Hu HW, Spijkers P, Guo H, Song X, Lenting PJ, Van Nostrand WE, Zlokovic BV.

Neuron. 2004 Aug 5;43(3):333-44.

PMID:
15294142
[PubMed - indexed for MEDLINE]
3.

Method for measurement of the blood-brain barrier permeability in the perfused mouse brain: application to amyloid-beta peptide in wild type and Alzheimer's Tg2576 mice.

LaRue B, Hogg E, Sagare A, Jovanovic S, Maness L, Maurer C, Deane R, Zlokovic BV.

J Neurosci Methods. 2004 Sep 30;138(1-2):233-42.

PMID:
15325132
[PubMed - indexed for MEDLINE]
4.

Pharmacokinetic analysis of the blood-brain barrier transport of 125I-amyloid beta protein 40 in wild-type and Alzheimer's disease transgenic mice (APP,PS1) and its implications for amyloid plaque formation.

Kandimalla KK, Curran GL, Holasek SS, Gilles EJ, Wengenack TM, Poduslo JF.

J Pharmacol Exp Ther. 2005 Jun;313(3):1370-8. Epub 2005 Mar 2.

PMID:
15743932
[PubMed - indexed for MEDLINE]
Free Article
5.

Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.

Deane R, Bell RD, Sagare A, Zlokovic BV.

CNS Neurol Disord Drug Targets. 2009 Mar;8(1):16-30. Review.

PMID:
19275634
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Permeability of proteins at the blood-brain barrier in the normal adult mouse and double transgenic mouse model of Alzheimer's disease.

Poduslo JF, Curran GL, Wengenack TM, Malester B, Duff K.

Neurobiol Dis. 2001 Aug;8(4):555-67.

PMID:
11493021
[PubMed - indexed for MEDLINE]
7.

Downregulation of LRP1 [correction of LPR1] at the blood-brain barrier in streptozotocin-induced diabetic mice.

Hong H, Liu LP, Liao JM, Wang TS, Ye FY, Wu J, Wang YY, Wang Y, Li YQ, Long Y, Xia YZ.

Neuropharmacology. 2009 May-Jun;56(6-7):1054-9. doi: 10.1016/j.neuropharm.2009.03.001. Epub 2009 Mar 11.

PMID:
19285094
[PubMed - indexed for MEDLINE]
8.

Lack of brain-to-blood efflux transport activity of low-density lipoprotein receptor-related protein-1 (LRP-1) for amyloid-beta peptide(1-40) in mouse: involvement of an LRP-1-independent pathway.

Ito S, Ueno T, Ohtsuki S, Terasaki T.

J Neurochem. 2010 Jun;113(5):1356-63. doi: 10.1111/j.1471-4159.2010.06708.x. Epub 2010 Mar 26.

PMID:
20367755
[PubMed - indexed for MEDLINE]
9.

Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives.

Wang YJ, Zhou HD, Zhou XF.

Drug Discov Today. 2006 Oct;11(19-20):931-8. Epub 2006 Sep 7. Review.

PMID:
16997144
[PubMed - indexed for MEDLINE]
10.

Cerebral clearance of human amyloid-beta peptide (1-40) across the blood-brain barrier is reduced by self-aggregation and formation of low-density lipoprotein receptor-related protein-1 ligand complexes.

Ito S, Ohtsuki S, Kamiie J, Nezu Y, Terasaki T.

J Neurochem. 2007 Dec;103(6):2482-90. Epub 2007 Oct 1.

PMID:
17908238
[PubMed - indexed for MEDLINE]
11.

Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits.

Yao J, Petanceska SS, Montine TJ, Holtzman DM, Schmidt SD, Parker CA, Callahan MJ, Lipinski WJ, Bisgaier CL, Turner BA, Nixon RA, Martins RN, Ouimet C, Smith JD, Davies P, Laska E, Ehrlich ME, Walker LC, Mathews PM, Gandy S.

J Neurochem. 2004 Aug;90(4):1011-8.

PMID:
15287908
[PubMed - indexed for MEDLINE]
12.

Targeting beta-amyloid pathology in Alzheimer's disease with Abeta immunotherapy.

Nitsch RM, Hock C.

Neurotherapeutics. 2008 Jul;5(3):415-20. doi: 10.1016/j.nurt.2008.05.013. Review.

PMID:
18625453
[PubMed - indexed for MEDLINE]
13.

apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain.

Deane R, Sagare A, Hamm K, Parisi M, Lane S, Finn MB, Holtzman DM, Zlokovic BV.

J Clin Invest. 2008 Dec;118(12):4002-13. doi: 10.1172/JCI36663. Epub 2008 Nov 13.

PMID:
19033669
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

ABCG2- and ABCG4-mediated efflux of amyloid-β peptide 1-40 at the mouse blood-brain barrier.

Do TM, Noel-Hudson MS, Ribes S, Besengez C, Smirnova M, Cisternino S, Buyse M, Calon F, Chimini G, Chacun H, Scherrmann JM, Farinotti R, Bourasset F.

J Alzheimers Dis. 2012;30(1):155-66. doi: 10.3233/JAD-2012-112189.

PMID:
22391220
[PubMed - indexed for MEDLINE]
15.

Selective dihydropyiridine compounds facilitate the clearance of β-amyloid across the blood-brain barrier.

Bachmeier C, Beaulieu-Abdelahad D, Mullan M, Paris D.

Eur J Pharmacol. 2011 Jun 1;659(2-3):124-9. doi: 10.1016/j.ejphar.2011.03.048. Epub 2011 Apr 9.

PMID:
21497592
[PubMed - indexed for MEDLINE]
16.

Copper complexing decreases the ability of amyloid beta peptide to cross the BBB and enter brain parenchyma.

Mare S, Penugonda S, Robinson SM, Dohgu S, Banks WA, Ercal N.

Peptides. 2007 Jul;28(7):1424-32. Epub 2007 May 18.

PMID:
17580097
[PubMed - indexed for MEDLINE]
17.

LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier.

Pflanzner T, Janko MC, André-Dohmen B, Reuss S, Weggen S, Roebroek AJ, Kuhlmann CR, Pietrzik CU.

Neurobiol Aging. 2011 Dec;32(12):2323.e1-11. doi: 10.1016/j.neurobiolaging.2010.05.025. Epub 2010 Jul 13.

PMID:
20630619
[PubMed - indexed for MEDLINE]
18.

Antibody-mediated immunotherapy for Alzheimer's disease.

Solomon B.

Curr Opin Investig Drugs. 2007 Jul;8(7):519-24. Review.

PMID:
17659471
[PubMed - indexed for MEDLINE]
19.

Experimental investigation of antibody-mediated clearance mechanisms of amyloid-beta in CNS of Tg-SwDI transgenic mice.

Vasilevko V, Xu F, Previti ML, Van Nostrand WE, Cribbs DH.

J Neurosci. 2007 Dec 5;27(49):13376-83.

PMID:
18057195
[PubMed - indexed for MEDLINE]
Free Article
20.

Detection of amyloid plaques by radioligands for Abeta40 and Abeta42: potential imaging agents in Alzheimer's patients.

Kung MP, Skovronsky DM, Hou C, Zhuang ZP, Gur TL, Zhang B, Trojanowski JQ, Lee VM, Kung HF.

J Mol Neurosci. 2003 Feb;20(1):15-24.

PMID:
12663930
[PubMed - indexed for MEDLINE]

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