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16303147,15572274,15567338,16515773,18054104,18235988,15313025,11170726,17429058,18573265,19631714,10529724,18586394,15499605,16573658,17920944,21903118,15013024,12392201,19545563,15736157,16405514,15777746,16678218,15721991,15114626,12422368,16519673,15710490,19401171,19520064,11161607,11170221,15596247,15614202,16580056,18606547,16533572,20566832,20187987,12673835,15159144,17067291,16011487,21262257,18977411,17486689,22708926,23747572,20079141,26827716,15313033,15936837,16831462,18204968,16385585,12938735,17714494,18702732,10437162,15327754,20227465,12872288,16045485,18648914,18577498,9668673,24333323,20067021,22178176,18457816,15447662,22402244,7696626,18755240,15248294,18662333,14734632,18806951,18076869,11578843,17156378,7825121,15313429,16806180,26006269,18420351,15589033,15207325,16006012,21736911,14523625,21906664,15790534,17469135,19027004,12626429,20197696,16564034,18942673,16959318,8739629,21092260,12322787,26686287,24607817,16712929,19765187,17359968,10222117,18991877,31418048,17519111,20546706,16624731,12387363,19632286,20440202,3262153,17439923,21195155,18382281,18030609,15790541,8643444,19245369,18823368,16209898,12764627,16551646,21731080,17565007,16581184,17880941,17076657,22634505,17397812,23083629,12639719,17995935,21571045,21788124,19429044,2571719,12153485,14561848,20629656,16198485,15787691,15970626,19908287,12822832,20882760,11335886,18032633,19804765,11684056,11724929,7530297,15056469,15589515,36054693,15585408,12900079,22138428,25108167,10817604,22921927,15111020,22885234,21558280,11180504,24657313,15935208,10581083,15464991,24871044,30582934,15474362,9682023,29427283,26648012,25837927,26593210,10077975,14975705,15755479,22414866,28369799,15939479,14630699,16181414,11780305,7884400,22427327,11535810,15525288,10222114,10591048,26210618,8967972,15850669,18425568,15958304,15833595,22617635,12388632,15910760,1578260,1975765,23810671,8782460,3878557,19370411,2901058,7684224,23347961,11720717,21190833,16157030,15016479,12230953,11880505,30031172,16126396,21172413,25678053,17515828,12880486,22155743,25680233,23422467,16214209,25968939,26203861,10802035,25541039,23665943,20035793,16187208,20411784,3103384,26045742,21473798,12923073,15000882,15694258,23123945,24593945,9488505,20540993,11225513,15723346,20001109,7542537,10543426,10581396,20925384,2868908,16236481,29332269,16237536,3493625,8540762,15473988,29158176,15451049,27484986,26464310,18423111,20307492,26988860,10529477,28366809,26244281,12898343,20431930,11206588,16716528,8876997,21804220,18616261,30107349,15733082,15105275,29032054,15882931,28800639,21448659,33172035,11591459,29460114,26409043,23548600,24147739,18164516,15218106,32387710,21419832,24417082,12846987,9756328,16273081,16909002,21259327,10580713,24555241,8836983,26188143,28400118,19594327,19680807,16051392,7690973,22974722,25929185,19609632,23178948,15845104,20064549,12738074,12044637,7915317,11085318,17038483,31330885,2573405,9784281,9832165,10731084,16298531,6610213,15721171,12579817,9056390,29577226,34047315,20676377,9795136,12076990,17574387,23159314,20957419,22480690,9326308,16787402,26434409,22266923,26227546,15626823,2239461,27265894,1502234,28006954,3489911,10435498,21180124,15920722,15978055,10704769,22056485,15569255,26332770,1502232,2871513,1350379,12866710,23758587,16005485,10574926,15305030,11113642,2434820,25907448,2898510,15236401,28982631,27624385,15716464,27235980,24795109,26994817,16023589,24726706,15694918,18093171,19666045,22446746,17883413,16181415,26511587,19726326,25968946,14675127,11172770,2858797,21318773,11698152,3493622,11553681,11604249,10799693,20819446,20173329,21476268,1445501,30179419,31703031,17583437,23821591,19635479,27251371,19428783,15079899,3878793,18340525,3002815,16973296,23062100,16165186,26028469,33242795,15575363,20951784,30501635,21737065,18840677,18328479,1712088,23512787,18224307,24726471,21376805,16288930,10505629,19500480,23933227,12663090,12498909,10399565,23296790,16210323,23184853,15219812,16144660,8748639,12402257,30413118,26683030,24995576,25929279,29196223,15707778,16154791,27306571,15909667,3126292,7902065,11996511,11958832,26292069,29217173,23830815,34560239,21688324,7884397,3121800,11872260,12932857,29656363,11226716,16603316,11259123,23563022,2827077,28807673,14711010,24414307,3502484,25989025,22108613,16179522,12552593,2510050,12600724,28185878,8910901,19629612,20382208,9219856,23501611,16154779,20347948,16298078,3494963,11462792,22513651,17768676,15946655,10863545,15312163,30310174,19998477,10640240,32474958,20114039,34258929,19000728,27788166,36526017,3210027,2413325,11121528,30241783,19794909,25242684,9848095,28161458,10991672,21970803,20969476,20600601,31562917,10318960,36303171,23536182,17586479,31479418,18941931,3502483,10095024,25274329,31480324,26940602,1350496,15718205,28601951,9503263,15816872,24223235,27960106,15363887,22387674,16463115,9636206,11205134,17196871,21320578,1353331,14657156,2215082,29519253,10335493,8931477,15897154,18797157,25362562,2616897,12670420,19616025,9763461,28875428,11470327,28190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Neuroprotective effect of arundic acid, an astrocyte-modulating agent, in mouse brain against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity.

Himeda T, Kadoguchi N, Kamiyama Y, Kato H, Maegawa H, Araki T. Himeda T, et al. Neuropharmacology. 2006 Mar;50(3):329-44. doi: 10.1016/j.neuropharm.2005.09.014. Epub 2005 Nov 21. Neuropharmacology. 2006. PMID: 16303147

Effect of angiotensin-converting enzyme inhibitor perindopril on interneurons in MPTP-treated mice.

Kurosaki R, Muramatsu Y, Kato H, Watanabe Y, Imai Y, Itoyama Y, Araki T. Kurosaki R, et al. Eur Neuropsychopharmacol. 2005 Jan;15(1):57-67. doi: 10.1016/j.euroneuro.2004.05.007. Eur Neuropsychopharmacol. 2005. PMID: 15572274

Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTP neurotoxicity in mice.

Kato H, Kurosaki R, Oki C, Araki T. Kato H, et al. Brain Res. 2004 Dec 24;1030(1):66-73. doi: 10.1016/j.brainres.2004.09.046. Brain Res. 2004. PMID: 15567338

Rifampicin attenuates the MPTP-induced neurotoxicity in mouse brain.

Oida Y, Kitaichi K, Nakayama H, Ito Y, Fujimoto Y, Shimazawa M, Nagai H, Hara H. Oida Y, et al. Brain Res. 2006 Apr 12;1082(1):196-204. doi: 10.1016/j.brainres.2006.01.116. Epub 2006 Mar 3. Brain Res. 2006. PMID: 16515773

Neuroprotective effects of genistein on dopaminergic neurons in the mice model of Parkinson's disease.

Liu LX, Chen WF, Xie JX, Wong MS. Liu LX, et al. Neurosci Res. 2008 Feb;60(2):156-61. doi: 10.1016/j.neures.2007.10.005. Epub 2007 Oct 23. Neurosci Res. 2008. PMID: 18054104

Role of reactive nitrogen and reactive oxygen species against MPTP neurotoxicity in mice.

Yokoyama H, Takagi S, Watanabe Y, Kato H, Araki T. Yokoyama H, et al. J Neural Transm (Vienna). 2008 Jun;115(6):831-42. doi: 10.1007/s00702-008-0019-6. Epub 2008 Jan 31. J Neural Transm (Vienna). 2008. PMID: 18235988

Effects of blocking the dopamine biosynthesis and of neurotoxic dopamine depletion with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on voluntary wheel running in mice.

Leng A, Mura A, Hengerer B, Feldon J, Ferger B. Leng A, et al. Behav Brain Res. 2004 Oct 5;154(2):375-83. doi: 10.1016/j.bbr.2004.03.004. Behav Brain Res. 2004. PMID: 15313025

Evidence for a dissociation between MPTP toxicity and tyrosinase activity based on congenic mouse strain susceptibility.

Hofele K, Sedelis M, Auburger GW, Morgan S, Huston JP, Schwarting RK. Hofele K, et al. Exp Neurol. 2001 Mar;168(1):116-22. doi: 10.1006/exnr.2000.7588. Exp Neurol. 2001. PMID: 11170726

Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a radical scavenger, prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the substantia nigra but not the striatum.

Kawasaki T, Ishihara K, Ago Y, Baba A, Matsuda T. Kawasaki T, et al. J Pharmacol Exp Ther. 2007 Jul;322(1):274-81. doi: 10.1124/jpet.106.119206. Epub 2007 Apr 11. J Pharmacol Exp Ther. 2007. PMID: 17429058

A neuroprotective agent, T-817MA (1-{3-[2-(1-benzothiophen-5-yl)ethoxy]propyl} azetidin-3-ol maleate), prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice.

Kawasaki T, Ago Y, Kitao T, Nashida T, Takagi A, Takuma K, Matsuda T. Kawasaki T, et al. Neuropharmacology. 2008 Oct;55(5):654-60. doi: 10.1016/j.neuropharm.2008.05.032. Epub 2008 Jun 5. Neuropharmacology. 2008. PMID: 18573265

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