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Items: 1 to 20 of 209

1.

The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol.

Borghese CM, Stórustovu Sí, Ebert B, Herd MB, Belelli D, Lambert JJ, Marshall G, Wafford KA, Harris RA.

J Pharmacol Exp Ther. 2006 Mar;316(3):1360-8. Epub 2005 Nov 4.

2.

Structure of alpha6 beta3 delta GABA(A) receptors and their lack of ethanol sensitivity.

Baur R, Kaur KH, Sigel E.

J Neurochem. 2009 Dec;111(5):1172-81. doi: 10.1111/j.1471-4159.2009.06387.x. Epub 2009 Sep 18.

3.

Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte.

Rahman M, Lindblad C, Johansson IM, Bäckström T, Wang MD.

Eur J Pharmacol. 2006 Oct 10;547(1-3):37-44. Epub 2006 Jul 27.

PMID:
16934248
4.
5.

An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice.

Borghese CM, Werner DF, Topf N, Baron NV, Henderson LA, Boehm SL 2nd, Blednov YA, Saad A, Dai S, Pearce RA, Harris RA, Homanics GE, Harrison NL.

J Pharmacol Exp Ther. 2006 Oct;319(1):208-18. Epub 2006 Jun 28.

6.

Etomidate, propofol and the neurosteroid THDOC increase the GABA efficacy of recombinant alpha4beta3delta and alpha4beta3 GABA A receptors expressed in HEK cells.

Meera P, Olsen RW, Otis TS, Wallner M.

Neuropharmacology. 2009 Jan;56(1):155-60. doi: 10.1016/j.neuropharm.2008.08.011. Epub 2008 Aug 20.

7.

Ethanol, flunitrazepam, and pentobarbital modulation of GABAA receptors expressed in mammalian cells and Xenopus oocytes.

Harris RA, Mihic SJ, Brozowski S, Hadingham K, Whiting PJ.

Alcohol Clin Exp Res. 1997 May;21(3):444-51.

PMID:
9161604
8.
9.

Functional consequences of GABAA receptor alpha 4 subunit deletion on synaptic and extrasynaptic currents in mouse dentate granule cells.

Liang J, Suryanarayanan A, Chandra D, Homanics GE, Olsen RW, Spigelman I.

Alcohol Clin Exp Res. 2008 Jan;32(1):19-26. Epub 2007 Dec 7.

PMID:
18070250
11.
12.

Effects of ethanol on tonic GABA currents in cerebellar granule cells and mammalian cells recombinantly expressing GABA(A) receptors.

Yamashita M, Marszalec W, Yeh JZ, Narahashi T.

J Pharmacol Exp Ther. 2006 Oct;319(1):431-8. Epub 2006 Jul 14.

13.

Proton sensitivity of the GABA(A) receptor is associated with the receptor subunit composition.

Krishek BJ, Amato A, Connolly CN, Moss SJ, Smart TG.

J Physiol. 1996 Apr 15;492 ( Pt 2):431-43.

14.

Unanticipated structural and functional properties of delta-subunit-containing GABAA receptors.

Kaur KH, Baur R, Sigel E.

J Biol Chem. 2009 Mar 20;284(12):7889-96. doi: 10.1074/jbc.M806484200. Epub 2009 Jan 13.

15.

Agonist function of the recombinant alpha 4 beta 3 delta GABAA receptor is dependent on the human and rat variants of the alpha 4-subunit.

Wang MD, Rahman M, Johansson IM, Bäckström T.

Clin Exp Pharmacol Physiol. 2010 Jul;37(7):662-9. doi: 10.1111/j.1440-1681.2010.05374.x. Epub 2010 Mar 12.

PMID:
20337660
16.

Early postnatal ethanol intubation blunts GABA(A) receptor up-regulation and modifies 3alpha-hydroxy-5alpha-pregnan-20-one sensitivity in rat MS/DB neurons.

Hsiao SH, Acevedo JL, DuBois DW, Smith KR, West JR, Frye GD.

Brain Res Dev Brain Res. 2001 Sep 23;130(1):25-40.

PMID:
11557091
17.

Subunit mutations affect ethanol actions on GABA(A) receptors expressed in Xenopus oocytes.

Ueno S, Wick MJ, Ye Q, Harrison NL, Harris RA.

Br J Pharmacol. 1999 May;127(2):377-82.

18.

The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors.

Belelli D, Casula A, Ling A, Lambert JJ.

Neuropharmacology. 2002 Sep;43(4):651-61.

PMID:
12367610
20.

Anesthetic-like modulation of receptor function by surfactants: a test of the interfacial theory of anesthesia.

Yang L, Sonner JM.

Anesth Analg. 2008 Sep;107(3):868-74. doi: 10.1213/ane.0b013e31817ee500.

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