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Results: 1 to 20 of 103

1.

Concomitant loss of dynorphin, NARP, and orexin in narcolepsy.

Crocker A, Espa├▒a RA, Papadopoulou M, Saper CB, Faraco J, Sakurai T, Honda M, Mignot E, Scammell TE.

Neurology. 2005 Oct 25;65(8):1184-8. Epub 2005 Sep 14.

PMID:
16247044
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Narp immunostaining of human hypocretin (orexin) neurons: loss in narcolepsy.

Blouin AM, Thannickal TC, Worley PF, Baraban JM, Reti IM, Siegel JM.

Neurology. 2005 Oct 25;65(8):1189-92. Epub 2005 Aug 31.

PMID:
16135770
[PubMed - indexed for MEDLINE]
3.

Narcolepsy: selective hypocretin (orexin) neuronal loss and multiple signaling deficiencies.

Bassetti CL.

Neurology. 2005 Oct 25;65(8):1152-3. No abstract available.

PMID:
16247037
[PubMed - indexed for MEDLINE]
4.

Orexin (hypocretin) neurons contain dynorphin.

Chou TC, Lee CE, Lu J, Elmquist JK, Hara J, Willie JT, Beuckmann CT, Chemelli RM, Sakurai T, Yanagisawa M, Saper CB, Scammell TE.

J Neurosci. 2001 Oct 1;21(19):RC168.

PMID:
11567079
[PubMed - indexed for MEDLINE]
Free Article
5.

In vivo evidence of neuronal loss in the hypothalamus of narcoleptic patients.

Lodi R, Tonon C, Vignatelli L, Iotti S, Montagna P, Barbiroli B, Plazzi G.

Neurology. 2004 Oct 26;63(8):1513-5.

PMID:
15505179
[PubMed - indexed for MEDLINE]
6.

Absence of ubiquitinated inclusions in hypocretin neurons of patients with narcolepsy.

Honda M, Arai T, Fukazawa M, Honda Y, Tsuchiya K, Salehi A, Akiyama H, Mignot E.

Neurology. 2009 Aug 18;73(7):511-7. doi: 10.1212/WNL.0b013e3181b2a6af.

PMID:
19687452
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients.

Cvetkovic-Lopes V, Bayer L, Dorsaz S, Maret S, Pradervand S, Dauvilliers Y, Lecendreux M, Lammers GJ, Donjacour CE, Du Pasquier RA, Pfister C, Petit B, Hor H, M├╝hlethaler M, Tafti M.

J Clin Invest. 2010 Mar;120(3):713-9. doi: 10.1172/JCI41366. Epub 2010 Feb 15.

PMID:
20160349
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The development of hypocretin (orexin) deficiency in hypocretin/ataxin-3 transgenic rats.

Zhang S, Lin L, Kaur S, Thankachan S, Blanco-Centurion C, Yanagisawa M, Mignot E, Shiromani PJ.

Neuroscience. 2007 Aug 10;148(1):34-43. Epub 2007 Jul 6.

PMID:
17618058
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Localized loss of hypocretin (orexin) cells in narcolepsy without cataplexy.

Thannickal TC, Nienhuis R, Siegel JM.

Sleep. 2009 Aug;32(8):993-8.

PMID:
19725250
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Symptomatic narcolepsy, cataplexy and hypersomnia, and their implications in the hypothalamic hypocretin/orexin system.

Nishino S, Kanbayashi T.

Sleep Med Rev. 2005 Aug;9(4):269-310. Review.

PMID:
16006155
[PubMed - indexed for MEDLINE]
11.

Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice.

Mieda M, Willie JT, Hara J, Sinton CM, Sakurai T, Yanagisawa M.

Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4649-54. Epub 2004 Mar 16.

PMID:
15070772
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The number of hypothalamic hypocretin (orexin) neurons is not affected in Prader-Willi syndrome.

Fronczek R, Lammers GJ, Balesar R, Unmehopa UA, Swaab DF.

J Clin Endocrinol Metab. 2005 Sep;90(9):5466-70. Epub 2005 Jun 28.

PMID:
15985489
[PubMed - indexed for MEDLINE]
13.

Orexin gene therapy restores the timing and maintenance of wakefulness in narcoleptic mice.

Kantor S, Mochizuki T, Lops SN, Ko B, Clain E, Clark E, Yamamoto M, Scammell TE.

Sleep. 2013 Aug 1;36(8):1129-38. doi: 10.5665/sleep.2870.

PMID:
23904672
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Selective expression of Narp, a secreted neuronal pentraxin, in orexin neurons.

Reti IM, Reddy R, Worley PF, Baraban JM.

J Neurochem. 2002 Sep;82(6):1561-5.

PMID:
12354306
[PubMed - indexed for MEDLINE]
15.

Expression of a poly-glutamine-ataxin-3 transgene in orexin neurons induces narcolepsy-cataplexy in the rat.

Beuckmann CT, Sinton CM, Williams SC, Richardson JA, Hammer RE, Sakurai T, Yanagisawa M.

J Neurosci. 2004 May 5;24(18):4469-77.

PMID:
15128861
[PubMed - indexed for MEDLINE]
Free Article
16.

Excitotoxic degeneration of hypothalamic orexin neurons in slice culture.

Katsuki H, Akaike A.

Neurobiol Dis. 2004 Feb;15(1):61-9.

PMID:
14751771
[PubMed - indexed for MEDLINE]
17.

Sleepiness that cannot be overcome: narcolepsy and cataplexy.

Han F.

Respirology. 2012 Nov;17(8):1157-65. doi: 10.1111/j.1440-1843.2012.02178.x. Review.

PMID:
22471619
[PubMed - indexed for MEDLINE]
Free Article
18.

Hypocretin/orexin and narcolepsy: new basic and clinical insights.

Nishino S, Okuro M, Kotorii N, Anegawa E, Ishimaru Y, Matsumura M, Kanbayashi T.

Acta Physiol (Oxf). 2010 Mar;198(3):209-22. doi: 10.1111/j.1748-1716.2009.02012.x. Epub 2009 Jun 25. Review.

PMID:
19555382
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Increase of histaminergic tuberomammillary neurons in narcolepsy.

Valko PO, Gavrilov YV, Yamamoto M, Reddy H, Haybaeck J, Mignot E, Baumann CR, Scammell TE.

Ann Neurol. 2013 Dec;74(6):794-804. doi: 10.1002/ana.24019.

PMID:
24006291
[PubMed - indexed for MEDLINE]
20.

Reduced number of hypocretin neurons in human narcolepsy.

Thannickal TC, Moore RY, Nienhuis R, Ramanathan L, Gulyani S, Aldrich M, Cornford M, Siegel JM.

Neuron. 2000 Sep;27(3):469-74.

PMID:
11055430
[PubMed - indexed for MEDLINE]
Free Article

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