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Results: 1 to 20 of 109

1.

Targeted antioxidative and neuroprotective properties of the dopamine agonist pramipexole and its nondopaminergic enantiomer SND919CL2x [(+)2-amino-4,5,6,7-tetrahydro-6-Lpropylamino-benzathiazole dihydrochloride].

Danzeisen R, Schwalenstoecker B, Gillardon F, Buerger E, Krzykalla V, Klinder K, Schild L, Hengerer B, Ludolph AC, Dorner-Ciossek C, Kussmaul L.

J Pharmacol Exp Ther. 2006 Jan;316(1):189-99. Epub 2005 Sep 27.

PMID:
16188953
[PubMed - indexed for MEDLINE]
Free Article
2.

KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine dihydrochloride monohydrate] for the treatment of amyotrophic lateral sclerosis.

Gribkoff VK, Bozik ME.

CNS Neurosci Ther. 2008 Fall;14(3):215-26. doi: 10.1111/j.1755-5949.2008.00048.x. Review.

PMID:
18801114
[PubMed - indexed for MEDLINE]
3.

Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms.

Gu M, Iravani MM, Cooper JM, King D, Jenner P, Schapira AH.

J Neurochem. 2004 Dec;91(5):1075-81. Erratum in: J Neurochem. 2005 Jan;92(1):215. Irvani, M [corrected to Iravani, MM].

PMID:
15569251
[PubMed - indexed for MEDLINE]
4.

Mitochondria-targeted antioxidant effects of S(-) and R(+) pramipexole.

Ferrari-Toninelli G, Maccarinelli G, Uberti D, Buerger E, Memo M.

BMC Pharmacol. 2010 Feb 5;10:2. doi: 10.1186/1471-2210-10-2.

PMID:
20137065
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Neuroprotection by pramipexole against dopamine- and levodopa-induced cytotoxicity.

Zou L, Jankovic J, Rowe DB, Xie W, Appel SH, Le W.

Life Sci. 1999;64(15):1275-85.

PMID:
10227583
[PubMed - indexed for MEDLINE]
6.

Pre-clinical studies of pramipexole: clinical relevance.

Hubble JP.

Eur J Neurol. 2000 May;7 Suppl 1:15-20. Review.

PMID:
11054154
[PubMed - indexed for MEDLINE]
7.
8.

Neuroprotective effects of the dopamine agonists pramipexole and bromocriptine in 3-acetylpyridine-treated rats.

Sethy VH, Wu H, Oostveen JA, Hall ED.

Brain Res. 1997 Apr 18;754(1-2):181-6.

PMID:
9134974
[PubMed - indexed for MEDLINE]
9.

Both the antioxidant and D3 agonist actions of pramipexole mediate its neuroprotective actions in mesencephalic cultures.

Ling ZD, Robie HC, Tong CW, Carvey PM.

J Pharmacol Exp Ther. 1999 Apr;289(1):202-10.

PMID:
10087005
[PubMed - indexed for MEDLINE]
Free Article
10.
11.

Antioxidant property of pramipexole independent of dopamine receptor activation in neuroprotection.

Le WD, Jankovic J, Xie W, Appel SH.

J Neural Transm. 2000;107(10):1165-73.

PMID:
11129106
[PubMed - indexed for MEDLINE]
12.

Pramipexole protects against H2O2-induced PC12 cell death.

Fujita Y, Izawa Y, Ali N, Kanematsu Y, Tsuchiya K, Hamano S, Tamaki T, Yoshizumi M.

Naunyn Schmiedebergs Arch Pharmacol. 2006 Jan;372(4):257-66. Epub 2005 Dec 16.

PMID:
16362428
[PubMed - indexed for MEDLINE]
13.

Dexpramipexole, the R(+) enantiomer of pramipexole, for the potential treatment of amyotrophic lateral sclerosis.

Cheah BC, Kiernan MC.

IDrugs. 2010 Dec;13(12):911-20. Review.

PMID:
21154151
[PubMed - indexed for MEDLINE]
14.

Neuroprotective effects of the dopamine D2/D3 agonist pramipexole against postischemic or methamphetamine-induced degeneration of nigrostriatal neurons.

Hall ED, Andrus PK, Oostveen JA, Althaus JS, VonVoigtlander PF.

Brain Res. 1996 Dec 2;742(1-2):80-8.

PMID:
9117424
[PubMed - indexed for MEDLINE]
15.

[Pharmacological profiles and clinical effects of antiparkinsonian agent, pramipexole].

Kohno Y, Takeuchi S.

Nihon Yakurigaku Zasshi. 2004 Jun;123(6):429-40. Review. Japanese.

PMID:
15170083
[PubMed - indexed for MEDLINE]
16.

Potential antidepressant properties of pramipexole detected in locomotor and operant behavioral investigations in mice.

Lehr E.

Psychopharmacology (Berl). 2002 Oct;163(3-4):495-500. Epub 2002 Aug 29.

PMID:
12373450
[PubMed - indexed for MEDLINE]
17.

Pramipexole has astrocyte-mediated neuroprotective effects against lactacystin toxicity.

Imamura K, Takeshima T, Nakaso K, Ito S, Nakashima K.

Neurosci Lett. 2008 Aug 1;440(2):97-102. doi: 10.1016/j.neulet.2008.05.067. Epub 2008 May 23.

PMID:
18555604
[PubMed - indexed for MEDLINE]
18.

Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms.

Ramirez AD, Wong SK, Menniti FS.

Eur J Pharmacol. 2003 Aug 15;475(1-3):29-35.

PMID:
12954356
[PubMed - indexed for MEDLINE]
19.

Validated chiral liquid chromatographic method for the enantiomeric separation of Pramipexole dihydrochloride monohydrate.

Pathare DB, Jadhav AS, Shingare MS.

J Pharm Biomed Anal. 2006 Jun 16;41(4):1152-6. Epub 2006 Mar 31.

PMID:
16580170
[PubMed - indexed for MEDLINE]
20.

Pharmacological approaches to counter the toxicity of Dopa.

VonVoigtlander PF, Fici GJ, Althaus JS.

Amino Acids. 1998;14(1-3):189-96.

PMID:
9871460
[PubMed - indexed for MEDLINE]

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