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Type 1 diabetes: evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families.

Concannon P, Erlich HA, Julier C, Morahan G, Nerup J, Pociot F, Todd JA, Rich SS; Type 1 Diabetes Genetics Consortium.

Diabetes. 2005 Oct;54(10):2995-3001.


Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families.

Cox NJ, Wapelhorst B, Morrison VA, Johnson L, Pinchuk L, Spielman RS, Todd JA, Concannon P.

Am J Hum Genet. 2001 Oct;69(4):820-30. Epub 2001 Aug 15.


Panning for gold: genome-wide scanning for linkage in type 1 diabetes.

Todd JA, Farrall M.

Hum Mol Genet. 1996;5 Spec No:1443-8. Review.


A German genome-wide linkage scan for type 2 diabetes supports the existence of a metabolic syndrome locus on chromosome 1p36.13 and a type 2 diabetes locus on chromosome 16p12.2.

Hoffmann K, Mattheisen M, Dahm S, Nürnberg P, Roe C, Johnson J, Cox NJ, Wichmann HE, Wienker TF, Schulze J, Schwarz PE, Lindner TH.

Diabetologia. 2007 Jul;50(7):1418-22. Epub 2007 Apr 27.


Evidence for a novel type 1 diabetes susceptibility locus on chromosome 8.

Sale MM, FitzGerald LM, Charlesworth JC, Bowden DW, Rich SS.

Diabetes. 2002 Dec;51 Suppl 3:S316-9.


Evidence of a non-MHC susceptibility locus in type I diabetes linked to HLA on chromosome 6.

Delépine M, Pociot F, Habita C, Hashimoto L, Froguel P, Rotter J, Cambon-Thomsen A, Deschamps I, Djoulah S, Weissenbach J, Nerup J, Lathrop M, Julier C.

Am J Hum Genet. 1997 Jan;60(1):174-87.


Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the Type 1 Diabetes Genetics Consortium.

Concannon P, Chen WM, Julier C, Morahan G, Akolkar B, Erlich HA, Hilner JE, Nerup J, Nierras C, Pociot F, Todd JA, Rich SS; Type 1 Diabetes Genetics Consortium.

Diabetes. 2009 Apr;58(4):1018-22. doi: 10.2337/db08-1551. Epub 2009 Jan 9.


A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27.

Francke S, Manraj M, Lacquemant C, Lecoeur C, Leprêtre F, Passa P, Hebe A, Corset L, Yan SL, Lahmidi S, Jankee S, Gunness TK, Ramjuttun US, Balgobin V, Dina C, Froguel P.

Hum Mol Genet. 2001 Nov 15;10(24):2751-65.


Evaluation of fine mapping strategies for a multifactorial disease locus: systematic linkage and association analysis of IDDM1 in the HLA region on chromosome 6p21.

Herr M, Dudbridge F, Zavattari P, Cucca F, Guja C, March R, Campbell RD, Barnett AH, Bain SC, Todd JA, Koeleman BP.

Hum Mol Genet. 2000 May 22;9(9):1291-301.


A genome-wide scan for type 1 diabetes susceptibility genes in nuclear families with multiple affected siblings in Finland.

Qiao Q, Osterholm AM, He B, Pitkäniemi J, Cordell HJ, Sarti C, Kinnunen L, Tuomilehto-Wolf E, Tryggvason K, Tuomilehto J.

BMC Genet. 2007 Dec 19;8:84.


Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24.

Vionnet N, Hani EH, Dupont S, Gallina S, Francke S, Dotte S, De Matos F, Durand E, Leprêtre F, Lecoeur C, Gallina P, Zekiri L, Dina C, Froguel P.

Am J Hum Genet. 2000 Dec;67(6):1470-80. Epub 2000 Nov 6.


Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome 11q.

Hashimoto L, Habita C, Beressi JP, Delepine M, Besse C, Cambon-Thomsen A, Deschamps I, Rotter JI, Djoulah S, James MR, et al.

Nature. 1994 Sep 8;371(6493):161-4.


A genome-wide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands.

Vaessen N, Heutink P, Houwing-Duistermaat JJ, Snijders PJ, Rademaker T, Testers L, Batstra MR, Sandkuijl LA, van Duijn CM, Oostra BA.

Diabetes. 2002 Mar;51(3):856-9.


A search for type 1 diabetes susceptibility genes in families from the United Kingdom.

Mein CA, Esposito L, Dunn MG, Johnson GC, Timms AE, Goy JV, Smith AN, Sebag-Montefiore L, Merriman ME, Wilson AJ, Pritchard LE, Cucca F, Barnett AH, Bain SC, Todd JA.

Nat Genet. 1998 Jul;19(3):297-300.


A genome-wide search for human type 1 diabetes susceptibility genes.

Davies JL, Kawaguchi Y, Bennett ST, Copeman JB, Cordell HJ, Pritchard LE, Reed PW, Gough SC, Jenkins SC, Palmer SM, et al.

Nature. 1994 Sep 8;371(6493):130-6.


Systemic lupus erythematosus genome scan: support for linkage at 1q23, 2q33, 16q12-13, and 17q21-23 and novel evidence at 3p24, 10q23-24, 13q32, and 18q22-23.

Cantor RM, Yuan J, Napier S, Kono N, Grossman JM, Hahn BH, Tsao BP.

Arthritis Rheum. 2004 Oct;50(10):3203-10.


A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions.

Nerup J, Pociot F; European Consortium for IDDM Studies.

Am J Hum Genet. 2001 Dec;69(6):1301-13. Epub 2001 Oct 11. Erratum in: Am J Hum Genet 2002 Apr;70(4):1075.


Genetics of type 1 diabetes.

Todd JA.

Pathol Biol (Paris). 1997 Mar;45(3):219-27. Review.

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