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Results: 1 to 20 of 151

1.

Acylation of lysine 860 allows tight binding and cytotoxicity of Bordetella adenylate cyclase on CD11b-expressing cells.

Masin J, Basler M, Knapp O, El-Azami-El-Idrissi M, Maier E, Konopasek I, Benz R, Leclerc C, Sebo P.

Biochemistry. 2005 Sep 27;44(38):12759-66.

PMID:
16171390
[PubMed - indexed for MEDLINE]
2.

Third activity of Bordetella adenylate cyclase (AC) toxin-hemolysin. Membrane translocation of AC domain polypeptide promotes calcium influx into CD11b+ monocytes independently of the catalytic and hemolytic activities.

Fiser R, Masín J, Basler M, Krusek J, Spuláková V, Konopásek I, Sebo P.

J Biol Chem. 2007 Feb 2;282(5):2808-20. Epub 2006 Dec 4.

PMID:
17148436
[PubMed - indexed for MEDLINE]
Free Article
3.

Interaction of Bordetella pertussis adenylate cyclase with CD11b/CD18: Role of toxin acylation and identification of the main integrin interaction domain.

El-Azami-El-Idrissi M, Bauche C, Loucka J, Osicka R, Sebo P, Ladant D, Leclerc C.

J Biol Chem. 2003 Oct 3;278(40):38514-21. Epub 2003 Jul 28.

PMID:
12885782
[PubMed - indexed for MEDLINE]
Free Article
4.

Pore-forming and enzymatic activities of Bordetella pertussis adenylate cyclase toxin synergize in promoting lysis of monocytes.

Basler M, Masin J, Osicka R, Sebo P.

Infect Immun. 2006 Apr;74(4):2207-14.

PMID:
16552051
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The conserved lysine 860 in the additional fatty-acylation site of Bordetella pertussis adenylate cyclase is crucial for toxin function independently of its acylation status.

Basar T, Havlícek V, Bezousková S, Halada P, Hackett M, Sebo P.

J Biol Chem. 1999 Apr 16;274(16):10777-83.

PMID:
10196151
[PubMed - indexed for MEDLINE]
Free Article
6.

Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and enzymatic activity in immunomodulation and cell death.

Boyd AP, Ross PJ, Conroy H, Mahon N, Lavelle EC, Mills KH.

J Immunol. 2005 Jul 15;175(2):730-8.

PMID:
16002668
[PubMed - indexed for MEDLINE]
Free Article
7.

Identification by in vitro complementation of regions required for cell-invasive activity of Bordetella pertussis adenylate cyclase toxin.

Iwaki M, Ullmann A, Sebo P.

Mol Microbiol. 1995 Sep;17(6):1015-24.

PMID:
8594322
[PubMed - indexed for MEDLINE]
8.
9.

Segments crucial for membrane translocation and pore-forming activity of Bordetella adenylate cyclase toxin.

Basler M, Knapp O, Masin J, Fiser R, Maier E, Benz R, Sebo P, Osicka R.

J Biol Chem. 2007 Apr 27;282(17):12419-29. Epub 2007 Mar 8.

PMID:
17347146
[PubMed - indexed for MEDLINE]
Free Article
10.

Functional and structural studies on different forms of the adenylate cyclase toxin of Bordetella pertussis.

Cheung GY, Kelly SM, Jess TJ, Prior S, Price NC, Parton R, Coote JG.

Microb Pathog. 2009 Jan;46(1):36-42. doi: 10.1016/j.micpath.2008.10.005. Epub 2008 Nov 1.

PMID:
18992319
[PubMed - indexed for MEDLINE]
11.

RTX cytotoxins recognize beta2 integrin receptors through N-linked oligosaccharides.

Morova J, Osicka R, Masin J, Sebo P.

Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5355-60. doi: 10.1073/pnas.0711400105. Epub 2008 Mar 28.

PMID:
18375764
[PubMed - indexed for MEDLINE]
Free PMC Article
12.
13.

Adenylate cyclase toxin translocates across target cell membrane without forming a pore.

Osickova A, Masin J, Fayolle C, Krusek J, Basler M, Pospisilova E, Leclerc C, Osicka R, Sebo P.

Mol Microbiol. 2010 Mar;75(6):1550-62. doi: 10.1111/j.1365-2958.2010.07077.x. Epub 2010 Feb 23.

PMID:
20199594
[PubMed - indexed for MEDLINE]
14.

Different structural requirements for adenylate cyclase toxin interactions with erythrocyte and liposome membranes.

Masín J, Konopásek I, Svobodová J, Sebo P.

Biochim Biophys Acta. 2004 Jan 28;1660(1-2):144-54.

PMID:
14757230
[PubMed - indexed for MEDLINE]
Free Article
15.

Bordetella pertussis adenylate cyclase toxin: proCyaA and CyaC proteins synthesised separately in Escherichia coli produce active toxin in vitro.

Westrop GD, Hormozi EK, Da Costa NA, Parton R, Coote JG.

Gene. 1996 Nov 21;180(1-2):91-9.

PMID:
8973351
[PubMed - indexed for MEDLINE]
16.

Adenylate cyclase toxin (CyaA) of Bordetella pertussis. Evidence for the formation of small ion-permeable channels and comparison with HlyA of Escherichia coli.

Benz R, Maier E, Ladant D, Ullmann A, Sebo P.

J Biol Chem. 1994 Nov 4;269(44):27231-9.

PMID:
7525549
[PubMed - indexed for MEDLINE]
Free Article
17.

Bordetella adenylate cyclase toxin induces a cascade of morphological changes of sheep erythrocytes and localizes into clusters in erythrocyte membranes.

Vojtová J, Kofronová O, Sebo P, Benada O.

Microsc Res Tech. 2006 Feb;69(2):119-29.

PMID:
16456835
[PubMed - indexed for MEDLINE]
18.

Mass spectrometric analysis of recombinant adenylate cyclase toxin from Bordetella pertussis strain 18323/pHSP9.

Havlícek V, Higgins L, Chen W, Halada P, Sebo P, Sakamoto H, Hackett M.

J Mass Spectrom. 2001 Apr;36(4):384-91.

PMID:
11333441
[PubMed - indexed for MEDLINE]
19.

Channel formation in model membranes by the adenylate cyclase toxin of Bordetella pertussis: effect of calcium.

Knapp O, Maier E, Polleichtner G, Masín J, Sebo P, Benz R.

Biochemistry. 2003 Jul 8;42(26):8077-84.

PMID:
12834359
[PubMed - indexed for MEDLINE]
20.

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