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Items: 1 to 20 of 157

1.

eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally.

Mata-Greenwood E, Jenkins C, Farrow KN, Konduri GG, Russell JA, Lakshminrusimha S, Black SM, Steinhorn RH.

Am J Physiol Lung Cell Mol Physiol. 2006 Feb;290(2):L232-41. Epub 2005 Sep 2.

PMID:
16143585
2.

Nitric oxide and superoxide generation from endothelial NOS: modulation by HSP90.

Sud N, Sharma S, Wiseman DA, Harmon C, Kumar S, Venema RC, Fineman JR, Black SM.

Am J Physiol Lung Cell Mol Physiol. 2007 Dec;293(6):L1444-53. Epub 2007 Sep 7. Erratum in: Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L1004.

PMID:
17827253
3.

Apocynin improves oxygenation and increases eNOS in persistent pulmonary hypertension of the newborn.

Wedgwood S, Lakshminrusimha S, Farrow KN, Czech L, Gugino SF, Soares F, Russell JA, Steinhorn RH.

Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15;302(6):L616-26. doi: 10.1152/ajplung.00064.2011. Epub 2011 Dec 23.

PMID:
22198908
4.

Sepiapterin improves angiogenesis of pulmonary artery endothelial cells with in utero pulmonary hypertension by recoupling endothelial nitric oxide synthase.

Teng RJ, Du J, Xu H, Bakhutashvili I, Eis A, Shi Y, Pritchard KA Jr, Konduri GG.

Am J Physiol Lung Cell Mol Physiol. 2011 Sep;301(3):L334-45. doi: 10.1152/ajplung.00316.2010. Epub 2011 May 27.

PMID:
21622842
5.

Tetrahydrobiopterin, but not L-arginine, decreases NO synthase uncoupling in cells expressing high levels of endothelial NO synthase.

Bevers LM, Braam B, Post JA, van Zonneveld AJ, Rabelink TJ, Koomans HA, Verhaar MC, Joles JA.

Hypertension. 2006 Jan;47(1):87-94. Epub 2005 Dec 12.

PMID:
16344367
6.

Caloric restriction reverses high-fat diet-induced endothelial dysfunction and vascular superoxide production in C57Bl/6 mice.

Ketonen J, Pilvi T, Mervaala E.

Heart Vessels. 2010 May;25(3):254-62. doi: 10.1007/s00380-009-1182-x. Epub 2010 May 29.

PMID:
20512454
7.

Oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with persistent pulmonary hypertension.

Konduri GG, Bakhutashvili I, Eis A, Pritchard K Jr.

Am J Physiol Heart Circ Physiol. 2007 Apr;292(4):H1812-20. Epub 2006 Dec 1.

PMID:
17142346
8.

Endothelial cell superoxide anion radical generation is not dependent on endothelial nitric oxide synthase-serine 1179 phosphorylation and endothelial nitric oxide synthase dimer/monomer distribution.

Whitsett J, Martásek P, Zhao H, Schauer DW, Hatakeyama K, Kalyanaraman B, Vásquez-Vivar J.

Free Radic Biol Med. 2006 Jun 1;40(11):2056-68. Epub 2006 Feb 20.

PMID:
16716906
9.

Endothelial dysfunction in rat adjuvant-induced arthritis: vascular superoxide production by NAD(P)H oxidase and uncoupled endothelial nitric oxide synthase.

Haruna Y, Morita Y, Komai N, Yada T, Sakuta T, Tomita N, Fox DA, Kashihara N.

Arthritis Rheum. 2006 Jun;54(6):1847-55.

PMID:
16729278
10.

Interaction of endothelial nitric oxide synthase with mitochondria regulates oxidative stress and function in fetal pulmonary artery endothelial cells.

Konduri GG, Afolayan AJ, Eis A, Pritchard KA Jr, Teng RJ.

Am J Physiol Lung Cell Mol Physiol. 2015 Nov 1;309(9):L1009-17. doi: 10.1152/ajplung.00386.2014. Epub 2015 Aug 28.

PMID:
26320159
11.

eNOS uncoupling and endothelial dysfunction in aged vessels.

Yang YM, Huang A, Kaley G, Sun D.

Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1829-36. doi: 10.1152/ajpheart.00230.2009. Epub 2009 Sep 18.

PMID:
19767531
12.

5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling.

Antoniades C, Shirodaria C, Warrick N, Cai S, de Bono J, Lee J, Leeson P, Neubauer S, Ratnatunga C, Pillai R, Refsum H, Channon KM.

Circulation. 2006 Sep 12;114(11):1193-201. Epub 2006 Aug 28.

PMID:
16940192
13.

Uncoupling of endothelial nitric oxide synthase in cerebral vasculature of Tg2576 mice.

Santhanam AV, d'Uscio LV, He T, Das P, Younkin SG, Katusic ZS.

J Neurochem. 2015 Sep;134(6):1129-38. doi: 10.1111/jnc.13205. Epub 2015 Jul 15.

PMID:
26111938
14.

The role of nitric oxide synthase-derived reactive oxygen species in the altered relaxation of pulmonary arteries from lambs with increased pulmonary blood flow.

Lakshminrusimha S, Wiseman D, Black SM, Russell JA, Gugino SF, Oishi P, Steinhorn RH, Fineman JR.

Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1491-7. Epub 2007 May 18.

PMID:
17513498
15.

Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes.

Bitar MS, Wahid S, Mustafa S, Al-Saleh E, Dhaunsi GS, Al-Mulla F.

Eur J Pharmacol. 2005 Mar 21;511(1):53-64.

PMID:
15777779
16.

Developmental programming of eNOS uncoupling and enhanced vascular oxidative stress in adult rats after transient neonatal oxygen exposure.

Yzydorczyk C, Comte B, Huyard F, Cloutier A, Germain N, Bertagnolli M, Nuyt AM.

J Cardiovasc Pharmacol. 2013 Jan;61(1):8-16. doi: 10.1097/FJC.0b013e318274d1c4.

PMID:
23011469
17.

Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells.

Sugiyama T, Levy BD, Michel T.

J Biol Chem. 2009 May 8;284(19):12691-700. doi: 10.1074/jbc.M809295200. Epub 2009 Mar 12.

PMID:
19286667
18.

Progressive dysfunction of nitric oxide synthase in a lamb model of chronically increased pulmonary blood flow: a role for oxidative stress.

Oishi PE, Wiseman DA, Sharma S, Kumar S, Hou Y, Datar SA, Azakie A, Johengen MJ, Harmon C, Fratz S, Fineman JR, Black SM.

Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L756-66. doi: 10.1152/ajplung.00146.2007. Epub 2008 Aug 29.

PMID:
18757524
19.
20.

Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells.

Chen Y, Medhora M, Falck JR, Pritchard KA Jr, Jacobs ER.

Am J Physiol Lung Cell Mol Physiol. 2006 Sep;291(3):L378-85. Epub 2006 May 5.

PMID:
16679377
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