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Results: 1 to 20 of 128

1.

Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation.

Cusson-Hermance N, Khurana S, Lee TH, Fitzgerald KA, Kelliher MA.

J Biol Chem. 2005 Nov 4;280(44):36560-6. Epub 2005 Aug 22.

PMID:
16115877
[PubMed - indexed for MEDLINE]
Free Article
2.

Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta.

Jiang Z, Mak TW, Sen G, Li X.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3533-8. Epub 2004 Feb 24.

PMID:
14982987
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex.

Youn HS, Lee JY, Fitzgerald KA, Young HA, Akira S, Hwang DH.

J Immunol. 2005 Sep 1;175(5):3339-46.

PMID:
16116226
[PubMed - indexed for MEDLINE]
Free Article
4.

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway.

Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O, Sugiyama M, Okabe M, Takeda K, Akira S.

Science. 2003 Aug 1;301(5633):640-3. Epub 2003 Jul 10.

PMID:
12855817
[PubMed - indexed for MEDLINE]
Free Article
5.

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo.

Shim JH, Xiao C, Paschal AE, Bailey ST, Rao P, Hayden MS, Lee KY, Bussey C, Steckel M, Tanaka N, Yamada G, Akira S, Matsumoto K, Ghosh S.

Genes Dev. 2005 Nov 15;19(22):2668-81. Epub 2005 Oct 31.

PMID:
16260493
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.

Lee TH, Shank J, Cusson N, Kelliher MA.

J Biol Chem. 2004 Aug 6;279(32):33185-91. Epub 2004 Jun 1.

PMID:
15175328
[PubMed - indexed for MEDLINE]
Free Article
7.

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation.

Meylan E, Burns K, Hofmann K, Blancheteau V, Martinon F, Kelliher M, Tschopp J.

Nat Immunol. 2004 May;5(5):503-7. Epub 2004 Apr 4.

PMID:
15064760
[PubMed - indexed for MEDLINE]
8.

Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of Toll-like receptor 3 and 4.

Aksoy E, Vanden Berghe W, Detienne S, Amraoui Z, Fitzgerald KA, Haegeman G, Goldman M, Willems F.

Eur J Immunol. 2005 Jul;35(7):2200-9.

PMID:
15940673
[PubMed - indexed for MEDLINE]
9.

Suppression of MyD88- and TRIF-dependent signaling pathways of Toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea.

Youn HS, Lee JY, Saitoh SI, Miyake K, Kang KW, Choi YJ, Hwang DH.

Biochem Pharmacol. 2006 Sep 28;72(7):850-9. Epub 2006 Aug 4.

PMID:
16890209
[PubMed - indexed for MEDLINE]
10.

Transforming growth factor-beta differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling.

Naiki Y, Michelsen KS, Zhang W, Chen S, Doherty TM, Arditi M.

J Biol Chem. 2005 Feb 18;280(7):5491-5. Epub 2004 Dec 28.

PMID:
15623538
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

Acrolein with an alpha, beta-unsaturated carbonyl group inhibits LPS-induced homodimerization of toll-like receptor 4.

Lee JS, Lee JY, Lee MY, Hwang DH, Youn HS.

Mol Cells. 2008 Apr 30;25(2):253-7. Epub 2008 Mar 31.

PMID:
18414004
[PubMed - indexed for MEDLINE]
Free Article
13.

WDR34 is a novel TAK1-associated suppressor of the IL-1R/TLR3/TLR4-induced NF-kappaB activation pathway.

Gao D, Wang R, Li B, Yang Y, Zhai Z, Chen DY.

Cell Mol Life Sci. 2009 Aug;66(15):2573-84. doi: 10.1007/s00018-009-0059-6. Epub 2009 Jun 12.

PMID:
19521662
[PubMed - indexed for MEDLINE]
14.

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF.

Fitzgerald KA, Rowe DC, Barnes BJ, Caffrey DR, Visintin A, Latz E, Monks B, Pitha PM, Golenbock DT.

J Exp Med. 2003 Oct 6;198(7):1043-55. Epub 2003 Sep 29. Erratum in: J Exp Med. 2003 Nov 3;198(9):following 1450.

PMID:
14517278
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The role of MyD88 and TLR4 in the LPS-mimetic activity of Taxol.

Byrd-Leifer CA, Block EF, Takeda K, Akira S, Ding A.

Eur J Immunol. 2001 Aug;31(8):2448-57.

PMID:
11500829
[PubMed - indexed for MEDLINE]
16.

Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP.

Andreakos E, Sacre SM, Smith C, Lundberg A, Kiriakidis S, Stonehouse T, Monaco C, Feldmann M, Foxwell BM.

Blood. 2004 Mar 15;103(6):2229-37. Epub 2003 Nov 20.

PMID:
14630816
[PubMed - indexed for MEDLINE]
Free Article
17.

Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway.

He S, Liang Y, Shao F, Wang X.

Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20054-9. doi: 10.1073/pnas.1116302108. Epub 2011 Nov 28.

PMID:
22123964
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inhibition of homodimerization of Toll-like receptor 4 by curcumin.

Youn HS, Saitoh SI, Miyake K, Hwang DH.

Biochem Pharmacol. 2006 Jun 28;72(1):62-9. Epub 2006 Apr 1.

PMID:
16678799
[PubMed - indexed for MEDLINE]
20.

Achieving stability of lipopolysaccharide-induced NF-kappaB activation.

Covert MW, Leung TH, Gaston JE, Baltimore D.

Science. 2005 Sep 16;309(5742):1854-7.

PMID:
16166516
[PubMed - indexed for MEDLINE]
Free Article

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