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Results: 1 to 20 of 111

1.

Common binding site for disialyllactose and tri-peptide in C-fragment of tetanus neurotoxin.

Jayaraman S, Eswaramoorthy S, Kumaran D, Swaminathan S.

Proteins. 2005 Nov 1;61(2):288-95.

PMID:
16104015
[PubMed - indexed for MEDLINE]
2.
3.

The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction.

Rummel A, Mahrhold S, Bigalke H, Binz T.

Mol Microbiol. 2004 Feb;51(3):631-43.

PMID:
14731268
[PubMed - indexed for MEDLINE]
4.

Sequence homology and structural analysis of the clostridial neurotoxins.

Lacy DB, Stevens RC.

J Mol Biol. 1999 Sep 3;291(5):1091-104.

PMID:
10518945
[PubMed - indexed for MEDLINE]
5.

Unique ganglioside recognition strategies for clostridial neurotoxins.

Benson MA, Fu Z, Kim JJ, Baldwin MR.

J Biol Chem. 2011 Sep 30;286(39):34015-22. doi: 10.1074/jbc.M111.272054. Epub 2011 Aug 17.

PMID:
21849494
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Structural analysis of the catalytic domain of tetanus neurotoxin.

Rao KN, Kumaran D, Binz T, Swaminathan S.

Toxicon. 2005 Jun 1;45(7):929-39. Epub 2005 Apr 13.

PMID:
15904688
[PubMed - indexed for MEDLINE]
7.

Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B.

Swaminathan S, Eswaramoorthy S.

Nat Struct Biol. 2000 Aug;7(8):693-9.

PMID:
10932256
[PubMed - indexed for MEDLINE]
8.

Substrate recognition of VAMP-2 by botulinum neurotoxin B and tetanus neurotoxin.

Chen S, Hall C, Barbieri JT.

J Biol Chem. 2008 Jul 25;283(30):21153-9. doi: 10.1074/jbc.M800611200. Epub 2008 May 29.

PMID:
18511417
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Active-site mutagenesis of tetanus neurotoxin implicates TYR-375 and GLU-271 in metalloproteolytic activity.

Rossetto O, Caccin P, Rigoni M, Tonello F, Bortoletto N, Stevens RC, Montecucco C.

Toxicon. 2001 Aug;39(8):1151-9.

PMID:
11306125
[PubMed - indexed for MEDLINE]
10.

Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.

Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.

Toxicon. 2013 Dec 1;75:108-21. doi: 10.1016/j.toxicon.2013.06.010. Epub 2013 Jun 29.

PMID:
23817019
[PubMed - indexed for MEDLINE]
11.

The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin.

Fotinou C, Emsley P, Black I, Ando H, Ishida H, Kiso M, Sinha KA, Fairweather NF, Isaacs NW.

J Biol Chem. 2001 Aug 24;276(34):32274-81. Epub 2001 Jun 19.

PMID:
11418600
[PubMed - indexed for MEDLINE]
Free Article
12.

Structure and function of tetanus and botulinum neurotoxins.

Montecucco C, Schiavo G.

Q Rev Biophys. 1995 Nov;28(4):423-72. Review.

PMID:
8771234
[PubMed - indexed for MEDLINE]
13.

Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.

Strotmeier J, Lee K, Völker AK, Mahrhold S, Zong Y, Zeiser J, Zhou J, Pich A, Bigalke H, Binz T, Rummel A, Jin R.

Biochem J. 2010 Oct 15;431(2):207-16. doi: 10.1042/BJ20101042.

PMID:
20704566
[PubMed - indexed for MEDLINE]
Free Article
14.

Molecular structures and functional relationships in clostridial neurotoxins.

Swaminathan S.

FEBS J. 2011 Dec;278(23):4467-85. doi: 10.1111/j.1742-4658.2011.08183.x. Epub 2011 Jun 13. Review.

PMID:
21592305
[PubMed - indexed for MEDLINE]
15.

The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.

Strotmeier J, Gu S, Jutzi S, Mahrhold S, Zhou J, Pich A, Eichner T, Bigalke H, Rummel A, Jin R, Binz T.

Mol Microbiol. 2011 Jul;81(1):143-56. doi: 10.1111/j.1365-2958.2011.07682.x. Epub 2011 Jun 2.

PMID:
21542861
[PubMed - indexed for MEDLINE]
16.

Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D.

Zhang Y, Gardberg AS, Edwards TE, Sankaran B, Robinson H, Varnum SM, Buchko GW.

Biochimie. 2013 Jul;95(7):1379-85. doi: 10.1016/j.biochi.2013.03.006. Epub 2013 Mar 21.

PMID:
23523511
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.

Karalewitz AP, Fu Z, Baldwin MR, Kim JJ, Barbieri JT.

J Biol Chem. 2012 Nov 23;287(48):40806-16. doi: 10.1074/jbc.M112.404244. Epub 2012 Oct 1.

PMID:
23027864
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mechanism of action of tetanus and botulinum neurotoxins.

Montecucco C, Schiavo G.

Mol Microbiol. 1994 Jul;13(1):1-8. Review.

PMID:
7527117
[PubMed - indexed for MEDLINE]
19.

Crystallographic evidence for doxorubicin binding to the receptor-binding site in Clostridium botulinum neurotoxin B.

Eswaramoorthy S, Kumaran D, Swaminathan S.

Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1743-6. Epub 2001 Oct 25.

PMID:
11679763
[PubMed - indexed for MEDLINE]
20.

Site-directed mutagenesis identifies active-site residues of the light chain of botulinum neurotoxin type A.

Rigoni M, Caccin P, Johnson EA, Montecucco C, Rossetto O.

Biochem Biophys Res Commun. 2001 Nov 16;288(5):1231-7.

PMID:
11700044
[PubMed - indexed for MEDLINE]

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