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Results: 1 to 20 of 111

1.

RalA and RalB: antagonistic relatives in cancer cell migration.

Oxford G, Owens CR, Titus BJ, Foreman TL, Herlevsen MC, Smith SC, Theodorescu D.

Cancer Res. 2005 Aug 15;65(16):7111-20.

PMID:
16103060
[PubMed - indexed for MEDLINE]
Free Article
2.

Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.

Lim KH, O'Hayer K, Adam SJ, Kendall SD, Campbell PM, Der CJ, Counter CM.

Curr Biol. 2006 Dec 19;16(24):2385-94.

PMID:
17174914
[PubMed - indexed for MEDLINE]
Free Article
3.

RalBP1 is necessary for metastasis of human cancer cell lines.

Wu Z, Owens C, Chandra N, Popovic K, Conaway M, Theodorescu D.

Neoplasia. 2010 Dec;12(12):1003-12.

PMID:
21170262
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Phosphorylation of RalB is important for bladder cancer cell growth and metastasis.

Wang H, Owens C, Chandra N, Conaway MR, Brautigan DL, Theodorescu D.

Cancer Res. 2010 Nov 1;70(21):8760-9. doi: 10.1158/0008-5472.CAN-10-0952. Epub 2010 Oct 12.

PMID:
20940393
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Involvement of RhoA and RalB in geranylgeranyltransferase I inhibitor-mediated inhibition of proliferation and migration of human oral squamous cell carcinoma cells.

Hamada M, Miki T, Iwai S, Shimizu H, Yura Y.

Cancer Chemother Pharmacol. 2011 Sep;68(3):559-69. doi: 10.1007/s00280-010-1520-9. Epub 2010 Nov 25.

PMID:
21107573
[PubMed - indexed for MEDLINE]
6.

Expression of ral GTPases, their effectors, and activators in human bladder cancer.

Smith SC, Oxford G, Baras AS, Owens C, Havaleshko D, Brautigan DL, Safo MK, Theodorescu D.

Clin Cancer Res. 2007 Jul 1;13(13):3803-13.

PMID:
17606711
[PubMed - indexed for MEDLINE]
Free Article
7.

Different metastasis promotive potency of small G-proteins RalA and RalB in in vivo hamster tumor model.

Rybko VA, Knizhnik AV, Komelkov AV, Aushev VN, Trukhanova LS, Tchevkina EM.

Cancer Cell Int. 2011 Jun 29;11(1):22. doi: 10.1186/1475-2867-11-22.

PMID:
21714887
[PubMed]
Free PMC Article
8.

Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.

Peschard P, McCarthy A, Leblanc-Dominguez V, Yeo M, Guichard S, Stamp G, Marshall CJ.

Curr Biol. 2012 Nov 6;22(21):2063-8. doi: 10.1016/j.cub.2012.09.013. Epub 2012 Oct 11.

PMID:
23063435
[PubMed - indexed for MEDLINE]
Free Article
9.

Expression profiling of Ral-depleted bladder cancer cells identifies RREB-1 as a novel transcriptional Ral effector.

Oxford G, Smith SC, Hampton G, Theodorescu D.

Oncogene. 2007 Nov 1;26(50):7143-52. Epub 2007 May 14.

PMID:
17496927
[PubMed - indexed for MEDLINE]
10.

Activation of RalA is critical for Ras-induced tumorigenesis of human cells.

Lim KH, Baines AT, Fiordalisi JJ, Shipitsin M, Feig LA, Cox AD, Der CJ, Counter CM.

Cancer Cell. 2005 Jun;7(6):533-45.

PMID:
15950903
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

The role of Ral A in epidermal growth factor receptor-regulated cell motility.

Gildea JJ, Harding MA, Seraj MJ, Gulding KM, Theodorescu D.

Cancer Res. 2002 Feb 15;62(4):982-5.

PMID:
11861368
[PubMed - indexed for MEDLINE]
Free Article
13.

The metastasis-associated gene CD24 is regulated by Ral GTPase and is a mediator of cell proliferation and survival in human cancer.

Smith SC, Oxford G, Wu Z, Nitz MD, Conaway M, Frierson HF, Hampton G, Theodorescu D.

Cancer Res. 2006 Feb 15;66(4):1917-22.

PMID:
16488989
[PubMed - indexed for MEDLINE]
Free Article
14.

Calmodulin binds RalA and RalB and is required for the thrombin-induced activation of Ral in human platelets.

Clough RR, Sidhu RS, Bhullar RP.

J Biol Chem. 2002 Aug 9;277(32):28972-80. Epub 2002 May 28.

PMID:
12034722
[PubMed - indexed for MEDLINE]
Free Article
15.

Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells.

Li TT, Alemayehu M, Aziziyeh AI, Pape C, Pampillo M, Postovit LM, Mills GB, Babwah AV, Bhattacharya M.

Mol Cancer Res. 2009 Jul;7(7):1064-77. doi: 10.1158/1541-7786.MCR-08-0578.

PMID:
19609003
[PubMed - indexed for MEDLINE]
Free Article
16.

Ral isoforms are implicated in Fc gamma R-mediated phagocytosis: activation of phospholipase D by RalA.

Corrotte M, Nyguyen AP, Harlay ML, Vitale N, Bader MF, Grant NJ.

J Immunol. 2010 Sep 1;185(5):2942-50. doi: 10.4049/jimmunol.0903138. Epub 2010 Aug 2.

PMID:
20679536
[PubMed - indexed for MEDLINE]
Free Article
17.

Immunodetection of ralA and ralB GTP-binding proteins in various rat tissues and platelets.

Bhullar RP, Yang S.

Mol Cell Biochem. 1998 Feb;179(1-2):49-55.

PMID:
9543348
[PubMed - indexed for MEDLINE]
18.

RalA and RalB function as the critical GTP sensors for GTP-dependent exocytosis.

Li G, Han L, Chou TC, Fujita Y, Arunachalam L, Xu A, Wong A, Chiew SK, Wan Q, Wang L, Sugita S.

J Neurosci. 2007 Jan 3;27(1):190-202.

PMID:
17202486
[PubMed - indexed for MEDLINE]
Free Article
19.

Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation.

Kidd AR 3rd, Snider JL, Martin TD, Graboski SF, Der CJ, Cox AD.

Int J Radiat Oncol Biol Phys. 2010 Sep 1;78(1):205-12. doi: 10.1016/j.ijrobp.2010.03.023. Epub 2010 Jul 7.

PMID:
20619549
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Transcriptional signatures of Ral GTPase are associated with aggressive clinicopathologic characteristics in human cancer.

Smith SC, Baras AS, Owens CR, Dancik G, Theodorescu D.

Cancer Res. 2012 Jul 15;72(14):3480-91. doi: 10.1158/0008-5472.CAN-11-3966. Epub 2012 May 14.

PMID:
22586063
[PubMed - indexed for MEDLINE]
Free PMC Article

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