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Results: 1 to 20 of 211

1.

Archazolid and apicularen: novel specific V-ATPase inhibitors.

Huss M, Sasse F, Kunze B, Jansen R, Steinmetz H, Ingenhorst G, Zeeck A, Wieczorek H.

BMC Biochem. 2005 Aug 4;6:13.

PMID:
16080788
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Inhibitors of V-ATPases: old and new players.

Huss M, Wieczorek H.

J Exp Biol. 2009 Feb;212(Pt 3):341-6. doi: 10.1242/jeb.024067. Review.

PMID:
19151208
[PubMed - indexed for MEDLINE]
Free Article
3.

The binding site of the V-ATPase inhibitor apicularen is in the vicinity of those for bafilomycin and archazolid.

Osteresch C, Bender T, Grond S, von Zezschwitz P, Kunze B, Jansen R, Huss M, Wieczorek H.

J Biol Chem. 2012 Sep 14;287(38):31866-76. doi: 10.1074/jbc.M112.372169. Epub 2012 Jul 19.

PMID:
22815478
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Concanamycin A, the specific inhibitor of V-ATPases, binds to the V(o) subunit c.

Huss M, Ingenhorst G, König S, Gassel M, Dröse S, Zeeck A, Altendorf K, Wieczorek H.

J Biol Chem. 2002 Oct 25;277(43):40544-8. Epub 2002 Aug 16.

PMID:
12186879
[PubMed - indexed for MEDLINE]
Free Article
5.

Inhibition of vacuolar-type (H+)-ATPase by the cytostatic macrolide apicularen A and its role in apicularen A-induced apoptosis in RAW 264.7 cells.

Hong J, Yokomakura A, Nakano Y, Ishihara K, Kaneda M, Onodera M, Nakahama K, Morita I, Niikura K, Ahn JW, Zee O, Ohuchi K.

FEBS Lett. 2006 May 15;580(11):2723-30. Epub 2006 Apr 21.

PMID:
16647709
[PubMed - indexed for MEDLINE]
Free Article
6.

Inhibition of bone resorption in cultures of mouse calvariae by apicularen A.

Hong J, Sasaki H, Niikura K, Yanai M, Nakano Y, Yokomakura A, Ishihara K, Hirasawa N, Kang YS, Oh JS, Kwak JH, Zee O, Ohuchi K.

Planta Med. 2007 Feb;73(2):173-5.

PMID:
17415879
[PubMed - indexed for MEDLINE]
7.

Archazolid A binds to the equatorial region of the c-ring of the vacuolar H+-ATPase.

Bockelmann S, Menche D, Rudolph S, Bender T, Grond S, von Zezschwitz P, Muench SP, Wieczorek H, Huss M.

J Biol Chem. 2010 Dec 3;285(49):38304-14. doi: 10.1074/jbc.M110.137539. Epub 2010 Sep 30.

PMID:
20884613
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Nitric oxide production by the vacuolar-type (H+)-ATPase inhibitors bafilomycin A1 and concanamycin A and its possible role in apoptosis in RAW 264.7 cells.

Hong J, Nakano Y, Yokomakura A, Ishihara K, Kim S, Kang YS, Ohuchi K.

J Pharmacol Exp Ther. 2006 Nov;319(2):672-81. Epub 2006 Aug 8.

PMID:
16895977
[PubMed - indexed for MEDLINE]
Free Article
9.

V-ATPase inhibitors and implication in cancer treatment.

Pérez-Sayáns M, Somoza-Martín JM, Barros-Angueira F, Rey JM, García-García A.

Cancer Treat Rev. 2009 Dec;35(8):707-13. doi: 10.1016/j.ctrv.2009.08.003. Epub 2009 Sep 15. Review.

PMID:
19758758
[PubMed - indexed for MEDLINE]
10.

Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1.

Xie XS, Padron D, Liao X, Wang J, Roth MG, De Brabander JK.

J Biol Chem. 2004 May 7;279(19):19755-63. Epub 2004 Mar 3.

PMID:
14998996
[PubMed - indexed for MEDLINE]
Free Article
11.

Stereochemical determination of Archazolid A and B, highly potent vacuolar-type ATPase inhibitors from the Myxobacterium Archangium gephyra.

Hassfeld J, Farès C, Steinmetz H, Carlomagno T, Menche D.

Org Lett. 2006 Oct 12;8(21):4751-4.

PMID:
17020294
[PubMed - indexed for MEDLINE]
12.

Biosynthetic investigations of the V-type ATPase inhibitors bafilomycin A1, B1 and concanamycin A.

Schuhmann T, Grond S.

J Antibiot (Tokyo). 2004 Oct;57(10):655-61.

PMID:
15638326
[PubMed - indexed for MEDLINE]
Free Article
13.

Cruentaren A, a highly cytotoxic benzolactone from Myxobacteria is a novel selective inhibitor of mitochondrial F1-ATPases.

Kunze B, Sasse F, Wieczorek H, Huss M.

FEBS Lett. 2007 Jul 24;581(18):3523-7. Epub 2007 Jul 3.

PMID:
17624334
[PubMed - indexed for MEDLINE]
Free Article
14.

Archazolid A-15-O-β-D-glucopyranoside and iso-archazolid B: potent V-ATPase inhibitory polyketides from the myxobacteria Cystobacter violaceus and Archangium gephyra.

Horstmann N, Essig S, Bockelmann S, Wieczorek H, Huss M, Sasse F, Menche D.

J Nat Prod. 2011 May 27;74(5):1100-5. doi: 10.1021/np200036v. Epub 2011 Apr 22.

PMID:
21513292
[PubMed - indexed for MEDLINE]
15.

Vacuolar H(+)-ATPases: intra- and intermolecular interactions.

Huss M, Vitavska O, Albertmelcher A, Bockelmann S, Nardmann C, Tabke K, Tiburcy F, Wieczorek H.

Eur J Cell Biol. 2011 Sep;90(9):688-95. doi: 10.1016/j.ejcb.2011.04.009. Epub 2011 Jun 2. Review.

PMID:
21640428
[PubMed - indexed for MEDLINE]
16.

Mutations in subunit C of the vacuolar ATPase confer resistance to bafilomycin and identify a conserved antibiotic binding site.

Bowman BJ, Bowman EJ.

J Biol Chem. 2002 Feb 8;277(6):3965-72. Epub 2001 Nov 27.

PMID:
11724795
[PubMed - indexed for MEDLINE]
Free Article
17.

Identification of a new chondropsin class of antitumor compound that selectively inhibits V-ATPases.

Bowman EJ, Gustafson KR, Bowman BJ, Boyd MR.

J Biol Chem. 2003 Nov 7;278(45):44147-52. Epub 2003 Aug 27.

PMID:
12944415
[PubMed - indexed for MEDLINE]
Free Article
18.

Cellular role of the V-ATPase in Neurospora crassa: analysis of mutants resistant to concanamycin or lacking the catalytic subunit A.

Bowman EJ, Bowman BJ.

J Exp Biol. 2000 Jan;203(Pt 1):97-106. Review.

PMID:
10600678
[PubMed - indexed for MEDLINE]
Free Article
19.

Semisynthetic derivatives of concanamycin A and C, as inhibitors of V- and P-type ATPases: structure-activity investigations and developments of photoaffinity probes.

Dröse S, Boddien C, Gassel M, Ingenhorst G, Zeeck A, Altendorf K.

Biochemistry. 2001 Mar 6;40(9):2816-25.

PMID:
11258892
[PubMed - indexed for MEDLINE]
20.

Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase.

Capell A, Liebscher S, Fellerer K, Brouwers N, Willem M, Lammich S, Gijselinck I, Bittner T, Carlson AM, Sasse F, Kunze B, Steinmetz H, Jansen R, Dormann D, Sleegers K, Cruts M, Herms J, Van Broeckhoven C, Haass C.

J Neurosci. 2011 Feb 2;31(5):1885-94. doi: 10.1523/JNEUROSCI.5757-10.2011.

PMID:
21289198
[PubMed - indexed for MEDLINE]
Free Article

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