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Results: 1 to 20 of 118

1.

Positive selection on a high-sensitivity allele of the human bitter-taste receptor TAS2R16.

Soranzo N, Bufe B, Sabeti PC, Wilson JF, Weale ME, Marguerie R, Meyerhof W, Goldstein DB.

Curr Biol. 2005 Jul 26;15(14):1257-65.

PMID:
16051168
[PubMed - indexed for MEDLINE]
Free Article
2.

Selection on the human bitter taste gene, TAS2R16, in Eurasian populations.

Li H, Pakstis AJ, Kidd JR, Kidd KK.

Hum Biol. 2011 Jun;83(3):363-77. doi: 10.3378/027.083.0303.

PMID:
21740153
[PubMed - indexed for MEDLINE]
3.

Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci.

Kim U, Wooding S, Ricci D, Jorde LB, Drayna D.

Hum Mutat. 2005 Sep;26(3):199-204.

PMID:
16086309
[PubMed - indexed for MEDLINE]
4.

The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.

Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W.

Nat Genet. 2002 Nov;32(3):397-401. Epub 2002 Oct 15.

PMID:
12379855
[PubMed - indexed for MEDLINE]
5.

Origin and differential selection of allelic variation at TAS2R16 associated with salicin bitter taste sensitivity in Africa.

Campbell MC, Ranciaro A, Zinshteyn D, Rawlings-Goss R, Hirbo J, Thompson S, Woldemeskel D, Froment A, Rucker JB, Omar SA, Bodo JM, Nyambo T, Belay G, Drayna D, Breslin PA, Tishkoff SA.

Mol Biol Evol. 2014 Feb;31(2):288-302. doi: 10.1093/molbev/mst211. Epub 2013 Oct 30.

PMID:
24177185
[PubMed - in process]
6.

Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin.

Wang JC, Hinrichs AL, Bertelsen S, Stock H, Budde JP, Dick DM, Bucholz KK, Rice J, Saccone N, Edenberg HJ, Hesselbrock V, Kuperman S, Schuckit MA, Bierut LJ, Goate AM.

Alcohol Clin Exp Res. 2007 Feb;31(2):209-15.

PMID:
17250611
[PubMed - indexed for MEDLINE]
7.

Evolution of functionally diverse alleles associated with PTC bitter taste sensitivity in Africa.

Campbell MC, Ranciaro A, Froment A, Hirbo J, Omar S, Bodo JM, Nyambo T, Lema G, Zinshteyn D, Drayna D, Breslin PA, Tishkoff SA.

Mol Biol Evol. 2012 Apr;29(4):1141-53. doi: 10.1093/molbev/msr293. Epub 2011 Nov 29.

PMID:
22130969
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Limited evidence for adaptive evolution and functional effect of allelic variation at rs702424 in the promoter of the TAS2R16 bitter taste receptor gene in Africa.

Campbell MC, Ranciaro A, Zinshteyn D, Rawlings-Goss R, Hirbo J, Thompson S, Woldemeskel D, Froment A, Omar SA, Bodo JM, Nyambo T, Belay G, Drayna D, Breslin PA, Tishkoff SA.

J Hum Genet. 2014 Jun;59(6):349-52. doi: 10.1038/jhg.2014.29. Epub 2014 May 1.

PMID:
24785689
[PubMed - in process]
9.

Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin.

Greene TA, Alarcon S, Thomas A, Berdougo E, Doranz BJ, Breslin PA, Rucker JB.

PLoS One. 2011;6(5):e20123. doi: 10.1371/journal.pone.0020123. Epub 2011 May 24.

PMID:
21629661
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Natural selection and molecular evolution in PTC, a bitter-taste receptor gene.

Wooding S, Kim UK, Bamshad MJ, Larsen J, Jorde LB, Drayna D.

Am J Hum Genet. 2004 Apr;74(4):637-46. Epub 2004 Mar 2.

PMID:
14997422
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genetics of individual differences in bitter taste perception: lessons from the PTC gene.

Kim UK, Drayna D.

Clin Genet. 2005 Apr;67(4):275-80. Review. Erratum in: Clin Genet. 2005 Jun;67(6):534.

PMID:
15733260
[PubMed - indexed for MEDLINE]
12.

Functional diversity of bitter taste receptor TAS2R16 in primates.

Imai H, Suzuki N, Ishimaru Y, Sakurai T, Yin L, Pan W, Abe K, Misaka T, Hirai H.

Biol Lett. 2012 Aug 23;8(4):652-6. doi: 10.1098/rsbl.2011.1251. Epub 2012 Mar 7.

PMID:
22399783
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Evolution: a study in bad taste?

Wooding S.

Curr Biol. 2005 Oct 11;15(19):R805-7. Review.

PMID:
16213813
[PubMed - indexed for MEDLINE]
Free Article
14.

Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence.

Hinrichs AL, Wang JC, Bufe B, Kwon JM, Budde J, Allen R, Bertelsen S, Evans W, Dick D, Rice J, Foroud T, Nurnberger J, Tischfield JA, Kuperman S, Crowe R, Hesselbrock V, Schuckit M, Almasy L, Porjesz B, Edenberg HJ, Begleiter H, Meyerhof W, Bierut LJ, Goate AM.

Am J Hum Genet. 2006 Jan;78(1):103-11. Epub 2005 Nov 21.

PMID:
16385453
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Positive selection drives the evolution of bat bitter taste receptor genes.

Zhou Y, Dong D, Zhang S, Zhao H.

Biochem Genet. 2009 Apr;47(3-4):207-15. doi: 10.1007/s10528-008-9218-y. Epub 2009 Feb 26.

PMID:
19242789
[PubMed - indexed for MEDLINE]
16.

Relaxation of selective constraint and loss of function in the evolution of human bitter taste receptor genes.

Wang X, Thomas SD, Zhang J.

Hum Mol Genet. 2004 Nov 1;13(21):2671-8. Epub 2004 Sep 14.

PMID:
15367488
[PubMed - indexed for MEDLINE]
Free Article
17.

Population genetics of CAPN10 and GPR35: implications for the evolution of type 2 diabetes variants.

Vander Molen J, Frisse LM, Fullerton SM, Qian Y, Del Bosque-Plata L, Hudson RR, Di Rienzo A.

Am J Hum Genet. 2005 Apr;76(4):548-60. Epub 2005 Feb 4.

PMID:
15696418
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The human bitter taste receptor, hTAS2R16, discriminates slight differences in the configuration of disaccharides.

Sakurai T, Misaka T, Ueno Y, Ishiguro M, Matsuo S, Ishimaru Y, Asakura T, Abe K.

Biochem Biophys Res Commun. 2010 Nov 26;402(4):595-601. doi: 10.1016/j.bbrc.2010.10.059. Epub 2010 Oct 20.

PMID:
20965151
[PubMed - indexed for MEDLINE]
19.

Gustatory expression pattern of the human TAS2R bitter receptor gene family reveals a heterogenous population of bitter responsive taste receptor cells.

Behrens M, Foerster S, Staehler F, Raguse JD, Meyerhof W.

J Neurosci. 2007 Nov 14;27(46):12630-40.

PMID:
18003842
[PubMed - indexed for MEDLINE]
Free Article
20.

Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.

Pronin AN, Xu H, Tang H, Zhang L, Li Q, Li X.

Curr Biol. 2007 Aug 21;17(16):1403-8.

PMID:
17702579
[PubMed - indexed for MEDLINE]
Free Article

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