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Results: 1 to 20 of 256

1.

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.

Garraway LA, Widlund HR, Rubin MA, Getz G, Berger AJ, Ramaswamy S, Beroukhim R, Milner DA, Granter SR, Du J, Lee C, Wagner SN, Li C, Golub TR, Rimm DL, Meyerson ML, Fisher DE, Sellers WR.

Nature. 2005 Jul 7;436(7047):117-22.

PMID:
16001072
[PubMed - indexed for MEDLINE]
Free Article
2.

"Lineage addiction" in human cancer: lessons from integrated genomics.

Garraway LA, Weir BA, Zhao X, Widlund H, Beroukhim R, Berger A, Rimm D, Rubin MA, Fisher DE, Meyerson ML, Sellers WR.

Cold Spring Harb Symp Quant Biol. 2005;70:25-34.

PMID:
16869735
[PubMed - indexed for MEDLINE]
3.

Microphthalmia-associated transcription factor gene amplification in metastatic melanoma is a prognostic marker for patient survival, but not a predictive marker for chemosensitivity and chemotherapy response.

Ugurel S, Houben R, Schrama D, Voigt H, Zapatka M, Schadendorf D, Bröcker EB, Becker JC.

Clin Cancer Res. 2007 Nov 1;13(21):6344-50.

PMID:
17975146
[PubMed - indexed for MEDLINE]
Free Article
4.

From integrated genomics to tumor lineage dependency.

Garraway LA, Sellers WR.

Cancer Res. 2006 Mar 1;66(5):2506-8. Review.

PMID:
16510564
[PubMed - indexed for MEDLINE]
Free Article
5.

Expression of genes for microphthalmia isoforms, Pax3 and MSG1, in human melanomas.

Vachtenheim J, Novotná H.

Cell Mol Biol (Noisy-le-grand). 1999 Nov;45(7):1075-82.

PMID:
10644012
[PubMed - indexed for MEDLINE]
6.

MITF: master regulator of melanocyte development and melanoma oncogene.

Levy C, Khaled M, Fisher DE.

Trends Mol Med. 2006 Sep;12(9):406-14. Epub 2006 Aug 8. Review.

PMID:
16899407
[PubMed - indexed for MEDLINE]
7.

Hypoxia-inducible factor 1{alpha} is a new target of microphthalmia-associated transcription factor (MITF) in melanoma cells.

Buscà R, Berra E, Gaggioli C, Khaled M, Bille K, Marchetti B, Thyss R, Fitsialos G, Larribère L, Bertolotto C, Virolle T, Barbry P, Pouysségur J, Ponzio G, Ballotti R.

J Cell Biol. 2005 Jul 4;170(1):49-59. Epub 2005 Jun 27.

PMID:
15983061
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.

McGill GG, Horstmann M, Widlund HR, Du J, Motyckova G, Nishimura EK, Lin YL, Ramaswamy S, Avery W, Ding HF, Jordan SA, Jackson IJ, Korsmeyer SJ, Golub TR, Fisher DE.

Cell. 2002 Jun 14;109(6):707-18.

PMID:
12086670
[PubMed - indexed for MEDLINE]
Free Article
9.

Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma.

Miller AJ, Du J, Rowan S, Hershey CL, Widlund HR, Fisher DE.

Cancer Res. 2004 Jan 15;64(2):509-16.

PMID:
14744763
[PubMed - indexed for MEDLINE]
Free Article
10.

Cancer biology: the weakest link?

Merlino G.

Nature. 2005 Jul 7;436(7047):33-5. No abstract available.

PMID:
16001050
[PubMed - indexed for MEDLINE]
11.

Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression.

Carreira S, Goodall J, Aksan I, La Rocca SA, Galibert MD, Denat L, Larue L, Goding CR.

Nature. 2005 Feb 17;433(7027):764-9.

PMID:
15716956
[PubMed - indexed for MEDLINE]
12.

A genomic screen identifies TYRO3 as a MITF regulator in melanoma.

Zhu S, Wurdak H, Wang Y, Galkin A, Tao H, Li J, Lyssiotis CA, Yan F, Tu BP, Miraglia L, Walker J, Sun F, Orth A, Schultz PG, Wu X.

Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17025-30. doi: 10.1073/pnas.0909292106. Epub 2009 Sep 23.

PMID:
19805117
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex genetic alterations in cervical cancer.

Kloth JN, Oosting J, van Wezel T, Szuhai K, Knijnenburg J, Gorter A, Kenter GG, Fleuren GJ, Jordanova ES.

BMC Genomics. 2007 Feb 20;8:53.

PMID:
17311676
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor.

Widlund HR, Horstmann MA, Price ER, Cui J, Lessnick SL, Wu M, He X, Fisher DE.

J Cell Biol. 2002 Sep 16;158(6):1079-87. Epub 2002 Sep 16.

PMID:
12235125
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Microphthalmia-associated transcription factor is a critical transcriptional regulator of melanoma inhibitor of apoptosis in melanomas.

Dynek JN, Chan SM, Liu J, Zha J, Fairbrother WJ, Vucic D.

Cancer Res. 2008 May 1;68(9):3124-32. doi: 10.1158/0008-5472.CAN-07-6622.

PMID:
18451137
[PubMed - indexed for MEDLINE]
Free Article
17.

Lineage dependency and lineage-survival oncogenes in human cancer.

Garraway LA, Sellers WR.

Nat Rev Cancer. 2006 Aug;6(8):593-602. Review. Erratum in: Nat Rev Cancer. 2006 Sep;6(9):742.

PMID:
16862190
[PubMed - indexed for MEDLINE]
18.

Somatic alterations in the melanoma genome: a high-resolution array-based comparative genomic hybridization study.

Gast A, Scherer D, Chen B, Bloethner S, Melchert S, Sucker A, Hemminki K, Schadendorf D, Kumar R.

Genes Chromosomes Cancer. 2010 Aug;49(8):733-45. doi: 10.1002/gcc.20785.

PMID:
20544847
[PubMed - indexed for MEDLINE]
19.

Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.

Du J, Widlund HR, Horstmann MA, Ramaswamy S, Ross K, Huber WE, Nishimura EK, Golub TR, Fisher DE.

Cancer Cell. 2004 Dec;6(6):565-76.

PMID:
15607961
[PubMed - indexed for MEDLINE]
Free Article
20.

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