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Items: 1 to 20 of 101

1.

Asthmatic changes in mice lacking T-bet are mediated by IL-13.

Finotto S, Hausding M, Doganci A, Maxeiner JH, Lehr HA, Luft C, Galle PR, Glimcher LH.

Int Immunol. 2005 Aug;17(8):993-1007. Epub 2005 Jul 6.

2.

Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet.

Finotto S, Neurath MF, Glickman JN, Qin S, Lehr HA, Green FH, Ackerman K, Haley K, Galle PR, Szabo SJ, Drazen JM, De Sanctis GT, Glimcher LH.

Science. 2002 Jan 11;295(5553):336-8.

4.

T-bet inhibits both TH2 cell-mediated eosinophil recruitment and TH17 cell-mediated neutrophil recruitment into the airways.

Fujiwara M, Hirose K, Kagami S, Takatori H, Wakashin H, Tamachi T, Watanabe N, Saito Y, Iwamoto I, Nakajima H.

J Allergy Clin Immunol. 2007 Mar;119(3):662-70.

PMID:
17336616
5.

T-bet deficiency facilitates airway colonization by Mycoplasma pulmonis in a murine model of asthma.

Bakshi CS, Malik M, Carrico PM, Sellati TJ.

J Immunol. 2006 Aug 1;177(3):1786-95.

6.

Restoration of T-box-containing protein expressed in T cells protects against allergen-induced asthma.

Park JW, Min HJ, Sohn JH, Kim JY, Hong JH, Sigrist KS, Glimcher LH, Hwang ES.

J Allergy Clin Immunol. 2009 Feb;123(2):479-85. doi: 10.1016/j.jaci.2008.10.035. Epub 2008 Dec 10.

PMID:
19081613
8.

The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells.

Venkayya R, Lam M, Willkom M, Grünig G, Corry DB, Erle DJ.

Am J Respir Cell Mol Biol. 2002 Feb;26(2):202-8.

PMID:
11804871
9.

Treatment of allergic airway inflammation and hyperresponsiveness by imiquimod modulating transcription factors T-bet and GATA-3.

Bian T, Yin KS, Jin SX, Zhang XL, Zhou JY, Ma XQ, Hu JJ, De W.

Chin Med J (Engl). 2006 Apr 20;119(8):640-8.

PMID:
16635408
10.
11.
12.

T-bet is essential for the progression of experimental autoimmune encephalomyelitis.

Nath N, Prasad R, Giri S, Singh AK, Singh I.

Immunology. 2006 Jul;118(3):384-91.

13.

Local blockade of IL-6R signaling induces lung CD4+ T cell apoptosis in a murine model of asthma via regulatory T cells.

Finotto S, Eigenbrod T, Karwot R, Boross I, Doganci A, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Rose-John S, Galle PR, Neurath MF.

Int Immunol. 2007 Jun;19(6):685-93. Epub 2007 May 11.

14.

IL-2 receptor beta-chain signaling controls immunosuppressive CD4+ T cells in the draining lymph nodes and lung during allergic airway inflammation in vivo.

Doganci A, Karwot R, Maxeiner JH, Scholtes P, Schmitt E, Neurath MF, Lehr HA, Ho IC, Finotto S.

J Immunol. 2008 Aug 1;181(3):1917-26.

15.

Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice.

Miyazaki Y, Inoue H, Matsumura M, Matsumoto K, Nakano T, Tsuda M, Hamano S, Yoshimura A, Yoshida H.

J Immunol. 2005 Aug 15;175(4):2401-7.

16.

Mechanism of interleukin-25 (IL-17E)-induced pulmonary inflammation and airways hyper-reactivity.

Sharkhuu T, Matthaei KI, Forbes E, Mahalingam S, Hogan SP, Hansbro PM, Foster PS.

Clin Exp Allergy. 2006 Dec;36(12):1575-83.

PMID:
17177681
17.

Activin A is an acute allergen-responsive cytokine and provides a link to TGF-beta-mediated airway remodeling in asthma.

Karagiannidis C, Hense G, Martin C, Epstein M, Rückert B, Mantel PY, Menz G, Uhlig S, Blaser K, Schmidt-Weber CB.

J Allergy Clin Immunol. 2006 Jan;117(1):111-8. Epub 2005 Nov 8.

PMID:
16387593
18.

TGF-beta and IL-13 synergistically increase eotaxin-1 production in human airway fibroblasts.

Wenzel SE, Trudeau JB, Barnes S, Zhou X, Cundall M, Westcott JY, McCord K, Chu HW.

J Immunol. 2002 Oct 15;169(8):4613-9.

19.

Increased bleomycin-induced lung injury in mice deficient in the transcription factor T-bet.

Xu J, Mora AL, LaVoy J, Brigham KL, Rojas M.

Am J Physiol Lung Cell Mol Physiol. 2006 Oct;291(4):L658-67. Epub 2006 Apr 28.

20.

IL-12 up-regulates T-bet independently of IFN-gamma in human CD4+ T cells.

Ylikoski E, Lund R, Kyläniemi M, Filén S, Kilpeläinen M, Savolainen J, Lahesmaa R.

Eur J Immunol. 2005 Nov;35(11):3297-306. Erratum in: Eur J Immunol. 2006 Apr;36(4):1058.

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