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Items: 1 to 20 of 93


Protection from experimental asthma by an endogenous bronchodilator.

Que LG, Liu L, Yan Y, Whitehead GS, Gavett SH, Schwartz DA, Stamler JS.

Science. 2005 Jun 10;308(5728):1618-21. Epub 2005 May 26.


Biomedicine. Asthmatics breathe easier when it's SNO-ing.

Gerard C.

Science. 2005 Jun 10;308(5728):1560-1. No abstract available.


S-nitrosoglutathione supplementation to ovalbumin-sensitized and -challenged mice ameliorates methacholine-induced bronchoconstriction.

Foster MW, Yang Z, Potts EN, Michael Foster W, Que LG.

Am J Physiol Lung Cell Mol Physiol. 2011 Nov;301(5):L739-44. doi: 10.1152/ajplung.00134.2011. Epub 2011 Jul 22. Retraction in: Am J Physiol Lung Cell Mol Physiol. 2015 May 1;308(9):L981.


Effects of endogenous superoxide anion and nitric oxide on cholinergic constriction of normal and hyperreactive guinea pig airways.

De Boer J, Pouw FM, Zaagsma J, Meurs H.

Am J Respir Crit Care Med. 1998 Dec;158(6):1784-9.


Kinetic and cellular characterization of novel inhibitors of S-nitrosoglutathione reductase.

Sanghani PC, Davis WI, Fears SL, Green SL, Zhai L, Tang Y, Martin E, Bryan NS, Sanghani SP.

J Biol Chem. 2009 Sep 4;284(36):24354-62. doi: 10.1074/jbc.M109.019919. Epub 2009 Jul 11.


Endogenous S-nitrosothiols protect against myocardial injury.

Lima B, Lam GK, Xie L, Diesen DL, Villamizar N, Nienaber J, Messina E, Bowles D, Kontos CD, Hare JM, Stamler JS, Rockman HA.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6297-302. doi: 10.1073/pnas.0901043106. Epub 2009 Mar 26.


Essential roles of S-nitrosothiols in vascular homeostasis and endotoxic shock.

Liu L, Yan Y, Zeng M, Zhang J, Hanes MA, Ahearn G, McMahon TJ, Dickfeld T, Marshall HE, Que LG, Stamler JS.

Cell. 2004 Feb 20;116(4):617-28.


S-nitrosoglutathione reductase: an important regulator in human asthma.

Que LG, Yang Z, Stamler JS, Lugogo NL, Kraft M.

Am J Respir Crit Care Med. 2009 Aug 1;180(3):226-31. doi: 10.1164/rccm.200901-0158OC. Epub 2009 Apr 24.


Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin.

Bratt JM, Franzi LM, Linderholm AL, Last MS, Kenyon NJ, Last JA.

Toxicol Appl Pharmacol. 2009 Feb 1;234(3):273-80. doi: 10.1016/j.taap.2008.10.007. Epub 2008 Nov 5.


Structure-activity relationship of pyrrole based S-nitrosoglutathione reductase inhibitors: carboxamide modification.

Sun X, Qiu J, Strong SA, Green LS, Wasley JW, Blonder JP, Colagiovanni DB, Stout AM, Mutka SC, Richards JP, Rosenthal GJ.

Bioorg Med Chem Lett. 2012 Mar 15;22(6):2338-42. doi: 10.1016/j.bmcl.2012.01.047. Epub 2012 Feb 2.


Increased arginase activity underlies allergen-induced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness.

Meurs H, McKay S, Maarsingh H, Hamer MA, Macic L, Molendijk N, Zaagsma J.

Br J Pharmacol. 2002 Jun;136(3):391-8.


Discovery of s-nitrosoglutathione reductase inhibitors: potential agents for the treatment of asthma and other inflammatory diseases.

Sun X, Wasley JW, Qiu J, Blonder JP, Stout AM, Green LS, Strong SA, Colagiovanni DB, Richards JP, Mutka SC, Chun L, Rosenthal GJ.

ACS Med Chem Lett. 2011 Mar 11;2(5):402-6. doi: 10.1021/ml200045s. eCollection 2011 May 12.


Role of nitric oxide and superoxide in allergen-induced airway hyperreactivity after the late asthmatic reaction in guinea-pigs.

de Boer J, Meurs H, Flendrig L, Koopal M, Zaagsma J.

Br J Pharmacol. 2001 Aug;133(8):1235-42.


Hypoxia-induced changes in protein s-nitrosylation in female mouse brainstem.

Palmer LA, Kimberly deRonde, Brown-Steinke K, Gunter S, Jyothikumar V, Forbes MS, Lewis SJ.

Am J Respir Cell Mol Biol. 2015 Jan;52(1):37-45. doi: 10.1165/rcmb.2013-0359OC.


GSNO reductase and beta2-adrenergic receptor gene-gene interaction: bronchodilator responsiveness to albuterol.

Choudhry S, Que LG, Yang Z, Liu L, Eng C, Kim SO, Kumar G, Thyne S, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Stamler JS, Burchard EG.

Pharmacogenet Genomics. 2010 Jun;20(6):351-8. doi: 10.1097/FPC.0b013e328337f992.


Acute inhibition of inducible nitric oxide synthase but not its absence suppresses asthma-like responses.

Landgraf RG, Russo M, Jancar S.

Eur J Pharmacol. 2005 Aug 22;518(2-3):212-20.


Gender differences in S-nitrosoglutathione reductase activity in the lung.

Brown-Steinke K, deRonde K, Yemen S, Palmer LA.

PLoS One. 2010 Nov 16;5(11):e14007. doi: 10.1371/journal.pone.0014007.


Deficiency of nitric oxide in allergen-induced airway hyperreactivity to contractile agonists after the early asthmatic reaction: an ex vivo study.

de Boer J, Meurs H, Coers W, Koopal M, Bottone AE, Visser AC, Timens W, Zaagsma J.

Br J Pharmacol. 1996 Nov;119(6):1109-16.


Discovery of potent and novel S-nitrosoglutathione reductase inhibitors devoid of cytochrome P450 activities.

Sun X, Qiu J, Strong SA, Green LS, Wasley JW, Blonder JP, Colagiovanni DB, Mutka SC, Stout AM, Richards JP, Rosenthal GJ.

Bioorg Med Chem Lett. 2011 Oct 1;21(19):5849-53. doi: 10.1016/j.bmcl.2011.07.103. Epub 2011 Aug 3.

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