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15890935,17722977,11485624,9126249,9813203,16827663,15033560,15730807,17251298,15890930,15890918,12768015,10544150,9222988,10357469,9721247,16298986,11333905,15857992,12490404,20660187,11752155,11264346,10339592,10890360,19320565,17418361,15018709,11997472,16227248,10590121,14671134,14645592,15588347,10933700,16415019,30541842,18003735,9696790,11264379,17121806,12634405,11278567,11788025,29237828,26512079,10559349,10756031,11689632,9491911,24884925,25313689,8369165,7506556,10364300,25165106,7514675,7684062,9420226,11529558,12584309,9811721,27881646,17411375,16160156,7512157,19321618,14963135,11024154,15613343,15308718,12954207,7972127,11679153,8573396,16284180,12368305,15588348,18822440,8676471,27643887,16501119,17182681,12487827,15665645,12186887,16378977,7543586,27654288,9721244,10888650,22954962,9000083,9168234,12230936,10400718,8551612,16501112,7534097,26491873,1493053,12829845,9643373,12077293,11134270,9824323,1280382,27143130,7832633,31694950,15016849,14505910,9632396,7504741,18796729,11602749,9882391,26525792,27809912,9833739,9371578,20573813,10364306,18480460,10888615,8627264,12414953,11709091,16699036,11907225,12163614,1284059,15613306,29343576,26962221,25785610,9261346,8615015,7632464,11711617,11861835,27998283,11836401,14592765,10938094,1279195,15767436,7690420,21209919,9499111,18240966,7540648,11327825,8676486,11069996,1376135,7538171,7504740,7506300,7888227,8973529,9460926,21216319,1637373,15784911,12804861,17239419,16476981,7690418,29618644,7522494,19193800,7517147,7525988,11581376,1717992,10092648,9811699,10380013,17301785,7527082,1602531,24819826,7686222,16035946,19281264,11861850,7511395,8890476,7545244,27071630,10400757,12908937,26889042,28938888,7527081,11461678,18815292,11177385,12406507,9658072,15567138,19019969,19390328,10627516,30842322,7520095,10364275,23237851,9430247,10196334,7783749,18507530,26039641,18036244,7507188,7688827,30538178,23596523,1812947,15983047,1696353,22971578,8887471,7505441,14990699,16478400,15113902,10644368,15767435,7576915,7678308,1456889,8363754,23369442,7546903,11522189,9462924,17537860,19004942,7745677,15905975,22876913,1457206,8573373,15045488,18160142,25421818,15795308,9811711,16809318,22933274,17609282,8152439,10798448,10954535,9339846,12646791,12368322,23237529,1381202,12610158,9343181,18957538,11883006,19692476,14990703,21818294,10369125,11160708,11507206,10438057,7533854,11356961,9591713,9870313,10758170,9373324,10233923,25351987,26629902,18045110,7888225,10331443,11118068,7503990,12444251,17580087,25275490,11602718,15890908,23745959,1718036,1717717,22157596,12970440,24284318,16603531,23843638,20164234,11238869,10482572,17686865,16720980,1380258,7636470,25186731,9696803,18090388,10585143,12667802,9491908,9765494,2015114,24676404,1689372,16966601,7794110,1374810,1380259,9573233,7506299,10559353,10823934,24696475,9557691,1720628,1717712,9151820,10803497,21835796,15113923,8522171,22018245,7527084,1382339,8627711,17977968,19632700,22403408,7688820,26491157,36270088,16140761,24587168,10029247,24569807,20421997,12072528,12350351,22419808,12857914,12502824,25122783,1548744,33883222,10380014,28490588,8057475,9371651,12134048,14505925,10200301,21795340,26625359,15919664,8369162,9971818,8995609,17507486,1727487,18519142,7527089,8573370,27428434,8035496,8627160,19478397,24828352,18837996,11689635,22128330,9420262,10196311,14610191,9282816,10475237,21569409,7786580,18353956,1588493,21383841,8911575,8176383,7687306,16631222,10775626,11566603,10559336,16699037,12483221,14517611,24465884,9653130,15827176,27178216,14581570,7530400,12504547,18833294,8811069,15929699,16001833,19264769,15113908,8217346,12477875,7677956,11375057,15194768,8554907,10801487,19494007,1768461,7682425,14512572,10978173,7544051,15220431,23369572,9576954,9499040,18804254,23754383,1718344,8189527,1377948,26083631,16248793,24859049,7511394,20089638,26259811,21525208,8411395,19678561,9135875,20463081,1703212,7525987,16611061,11734627,11162839,18815295,9733820,11489906,8455141,1718090,25997386,11600200,14585210,19136072,20686044,27368421,16702010,32724045,15890924,19692465,21646396,10756055,28539445,18524826,9256481,11533159,1961739,10221529,8798975,16160142,15107547,1370580,12597360,9261451,8137947,11788024,23549023,1702001,9890944,2190605,9641677,8634021,9358100,12477867,30976088,7678970,35584191,19018669,7693970,10651813,1636088,21760891,10448968,25807494,16690178,9934706,1700435,24146829,15320988,19837343,12502809,1380257,7531216,1283308,17409160,8417177,27128349,27003615,24583235,22624045,10438529,1380099,15650174,27815696,16971434,2370681,7511253,2078408,27438765,12575942,1489578,11738743,1370558,8207641,9499039,8035514,7517148,20158904,12556682,10659054,1457207,1433529,15795530,7510807,15867093,9007197,8068416,9339845,7681612,26760231,24314667,15183061,10628817,11064498,20923564,21715490,12072497,19680536,15994801,8822624,9261412,9534960,10985246,10221533,7684755,7769687,22888999,11533181,7576916,29491151,11861874,1376134,9029533,18076768,20504942,7540399,28521215,9971817,12270140,26687685,96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Page 1

Cryptic nature of a conserved, CD4-inducible V3 loop neutralization epitope in the native envelope glycoprotein oligomer of CCR5-restricted, but not CXCR4-using, primary human immunodeficiency virus type 1 strains.

Lusso P, Earl PL, Sironi F, Santoro F, Ripamonti C, Scarlatti G, Longhi R, Berger EA, Burastero SE. Lusso P, et al. J Virol. 2005 Jun;79(11):6957-68. doi: 10.1128/JVI.79.11.6957-6968.2005. J Virol. 2005. PMID: 15890935 Free PMC article.

V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies.

Laakso MM, Lee FH, Haggarty B, Agrawal C, Nolan KM, Biscone M, Romano J, Jordan AP, Leslie GJ, Meissner EG, Su L, Hoxie JA, Doms RW. Laakso MM, et al. PLoS Pathog. 2007 Aug 24;3(8):e117. doi: 10.1371/journal.ppat.0030117. PLoS Pathog. 2007. PMID: 17722977 Free PMC article.

Protection of neutralization epitopes in the V3 loop of oligomeric human immunodeficiency virus type 1 glycoprotein 120 by N-linked oligosaccharides in the V1 region.

Losman B, Bolmstedt A, Schønning K, Björndal A, Westin C, Fenyö EM, Olofsson S. Losman B, et al. AIDS Res Hum Retroviruses. 2001 Jul 20;17(11):1067-76. doi: 10.1089/088922201300343753. AIDS Res Hum Retroviruses. 2001. PMID: 11485624

Binding of antibodies to virion-associated gp120 molecules of primary-like human immunodeficiency virus type 1 (HIV-1) isolates: effect on HIV-1 infection of macrophages and peripheral blood mononuclear cells.

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